52 research outputs found
Quality of life in childhood epilepsy with lateralized epileptogenic foci
<p>Abstract</p> <p>Background</p> <p>Measuring quality of life (QOL) helps to delineate mechanisms underlying the interaction of disease and psychosocial factors. In adults, epileptic foci in the left temporal lobe led to lower QOL and higher depression and anxiety as compared to the right-sided foci. No study addressed the development of QOL disturbances depending on the lateralization of epileptogenic focus. The objective of our study was to examine QOL in children with lateralized epileptiform discharges.</p> <p>Methods</p> <p>Thirty-one parents of children with epilepsy filled the Health-Related Quality of Life in Childhood Epilepsy Questionnaire (QOLCE). Fifteen children had foci in the left hemisphere and sixteen in the right, as verified with Electroencephalography (EEG) examinations.</p> <p>Results</p> <p>We found a significant correlation between foci lateralization and reduced QOL (Spearman's rho = 0.361, p < 0.046). Children with right hemispheric foci exhibited lower overall QOL, particularly in five areas: anxiety, social-activities, stigma, general-health, and quality-of-life.</p> <p>Conclusions</p> <p>We demonstrated for the first time that in children left- and right-hemispheric foci were associated with discordant QOL scores. Unlike in adults, foci in the right hemisphere led to worse emotional and social functioning demonstrating that seizures impact the brain differentially during development.</p
Repair or replace ischemic mitral regurgitation during coronary artery bypass grafting? A meta-analysis
Patterns and dynamics of neutral lipid fatty acids in ants – implications for ecological studies
Padronização do diagnóstico de Blastocystis hominis por diferentes técnicas de coloração
The credit crunch: the collapse of Lehman Brothers - and a Hong Kong scheme to handle Lehman claims
Anthony Connerty (Barrister and Chartered Arbitrator) looks at the Lehman collapse - considering the background to the collapse of Lehman Brothers investment bank, claims related to the collapse, an example of a credit crunch claim, a criminal prosecution and a Hong Kong mediation and arbitration scheme aimed at dealing speedily with Lehman Brothers-related claims. Versions of this article have been published in Hong Kong in the January 2010 edition of Asian Dispute Review and in London in the July 9, 2010 edition of New Law Journal. Published in Amicus Curiae – Journal of the Society for Advanced Legal Studies at the Institute of Advanced Legal Studies. The Journal is produced by SALS at the IALS (Institute of Advanced Legal Studies, School of Advanced Study, University of London)
Effect of asymmetric crank arm lengths on performance-related variables in cyclists with an anatomical lower limb length discrepancy
The sexuality scripts constructed by nurses and an interface with attention of sexually transmited infection/HIV
Roteiros de sexualidade construídos por enfermeiros e a interface com a atenção em infecções sexualmente transmissíveis/HIV
Patterns and dynamics of neutral lipid fatty acids in ants – implications for ecological studies
Background: Trophic interactions are a fundamental aspect of ecosystem functioning, but often difficult to observe
directly. Several indirect techniques, such as fatty acid analysis, were developed to assess these interactions. Fatty
acid profiles may indicate dietary differences, while individual fatty acids can be used as biomarkers. Ants
are among the most important terrestrial animal groups, but little is known about their lipid metabolism,
and no study so far used fatty acids to study their trophic ecology. We set up a feeding experiment with
high- and low-fat food to elucidate patterns and dynamics of neutral lipid fatty acids (NLFAs) assimilation
in ants. We asked whether dietary fatty acids are assimilated through direct trophic transfer, how diet
influences NLFA total amounts and patterns over time, and whether these assimilation processes are similar
across species and life stages.
Results: Ants fed with high-fat food quickly accumulated specific dietary fatty acids (C18:2n6, C18:3n3 and
C18:3n6), compared to ants fed with low-fat food. Dietary fat content did not affect total body fat of workers or amounts
of fatty acids extensively biosynthesized by animals (C16:0, C18:0, C18:1n9). Larval development had a strong effect on the
composition and amounts of C16:0, C18:0 and C18:1n9. NLFA compositions reflected dietary differences, which became
more pronounced over time. Assimilation of specific dietary NLFAs was similar regardless of species or life stage, but
these factors affected dynamics of other NLFAs, composition and total fat.
Conclusions: We showed that ants accumulated certain dietary fatty acids via direct trophic transfer. Fat content of the
diet had no effect on lipids stored by ants, which were able to synthesize high amounts of NLFAs from a sugar-based
diet. Nevertheless, dietary NLFAs had a strong effect on metabolic dynamics and profiles. Fatty acids are a useful tool to
study trophic biology of ants, and could be applied in an ecological context, although factors that affect NLFA patterns
should be taken into account. Further studies should address which NLFAs can be used as biomarkers in natural ant
communities, and how factors other than diet affect fatty acid dynamics and composition of species with
distinct life histories
Adjunctive stimulant use in patients with bipolar disorder: treatment of residual depression and sedation
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