Chemoinformatics and artificial intelligence colloquium: progress and challenges in developing bioactive compounds

We report the main conclusions of the first Chemoinformatics and Artificial Intelligence Colloquium, Mexico City, June 15–17, 2022. Fifteen lectures were presented during a virtual public event with speakers from industry, academia, and non-for-profit organizations. Twelve hundred and ninety students and academics from more than 60 countries. During the meeting, applications, challenges, and opportunities in drug discovery, de novo drug design, ADME-Tox (absorption, distribution, metabolism, excretion and toxicity) property predictions, organic chemistry, peptides, and antibiotic resistance were discussed. The program along with the recordings of all sessions are freely available at https://www.difacquim.com/english/events/2022-colloquium/. © 2022, The Author(s).Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Measurements of the center-of-mass energies at BESIII via the di-muon process

From 2011 to 2014, the BESIII experiment collected about 5 fb-1 data at center-of-mass energies around 4 GeV for the studies of the charmonium-like and higher excited charmonium states. By analyzing the di-muon process e+e- → γISR/FSRμ+μ-, the center-of-mass energies of the data samples are measured with a precision of 0.8 MeV. The center-of-mass energy is found to be stable for most of the time during data taking

Search for the Theta+(1530) pentaquark in antiproton 4He annihilation at rest

A research has been made to look for a signature of the positive-strangeness baryon resonance Θ+(1530), which is expected to decay into pK0. A peak is observed in the pπ+π− invariant mass distribution in antiproton– 4He annihilation reactions at rest with production of two π+π− pairs with invariant mass close to the K0S mass. The annihilation reactions on 4He can involve two to four nucleons producing an energy blob characterized by high strangeness content. The peak is centred around 1560.0±3.7MeV and its width is very narrow. The statistical significance is 2.7; this value is considered of not sufficient significance to claim support of the Θ+. The data were collected with the Obelix spectrometer at the LEAR machine of CERN