Laboratory tests in uveitis - New developments in the analysis of local antibody production

Analysis of local intraocular antibody production is a valuable tool with which to confirm a suspected clinical diagnosis in uveitis. We have analysed paired serum and aqueous samples for the presence of specific antibodies against toxoplasma, cytomegalovirus, herpes simplex virus and varicella zoster virus. Of the patients retrospectively diagnosed as having toxoplasma chorioretinitis 75% had a positive antibody coefficient indicating specific antibody production in the eye. Local antibody production in the eye directed against CMV confirmed the suspected diagnosis of CMV retinitis in 50% of the AIDS patients investigated. So far we have not been able to demonstrate local antibody production against herpes simplex virus (26 samples tested). Two of three patients with acute retinal necrosis had a positive antibody coefficient against varicella zoster virus. Both of these patients had an even higher titer in the aqueous than in serum. Since the choice of therapy, in infectious uveitis, depends on the causative organisms, it is very important to confirm a suspected clinical diagnosis by means of aqueous humor analysi

Herschel/HIFI measurements of the ortho/para ratio in water towards Sagittarius B2(M) and W31C

We present Herschel/HIFI observations of the fundamental rotational transitions of ortho- and para-H16 2 O and H18 2 O in absorption towards Sagittarius B2(M) and W31C. The ortho/para ratio in water in the foreground clouds on the line of sight towards these bright continuum sources is generally consistent with the statistical high-temperature ratio of 3, within the observational uncertainties. However, somewhat unexpectedly, we derive a low ortho/para ratio of 2.35±0.35, corresponding to a spin temperature of ∼27 K, towards Sagittarius B2(M) at velocities of the expanding molecular ring. Water molecules in this region appear to have formed with, or relaxed to, an ortho/para ratio close to the value corresponding to the local temperature of the gas and dust

ISOTOPE SHIFTS AND HYPERFINE-STRUCTURE OF NATURAL DYSPROSIUM

Isotype shifts and hyperfine structure measurements for five transitions in natural dysprosium have been performed using a CW tunable dye laser and a collimated atomic beam. The consistency of experimental isotope shifts is tested and values of the change in rms radius of the nuclear charge distribution are calculated. © 1978

NUCLEAR SPINS OF SOME NEUTRON-DEFICIENT AS ISOTOPES

The nuclear spins of some neutron-deficient arsenic isotopes have been measured using the atomic beam magnetic resonance technique. The results are

HYPERFINE-STRUCTURE AND NUCLEAR MOMENTS OF SOME NEUTRON-DEFICIENT AS ISOTOPES

The hyperfine structure of th

HIGH-RESOLUTION STUDY OF TRANSITION -LAMBDA = 451.1 NM IN IN-I USING A CW DYE-LASER

The transition lambda =451.1 nm in a natural sample of In I has been studied with high-resolution techniques using a CW dye laser. The hyperfine-structure constant of th

HIGH-RESOLUTION STUDY OF THE TRANSITIONS 4F76S2-]4F76S6P IN THE EU-I-SPECTRUM

Eight transitions in the Eu I-spectrum connecting the ground state with configuration 4