Accuracy of citrulline, I-FABP and d-lactate in the diagnosis of acute mesenteric ischemia

Data availability: Research data are not shared.Supplementary Information oi available online at: https://www.nature.com/articles/s41598-021-98012-w#Sec14 .Early diagnosis of acute mesenteric ischemia (AMI) remains a clinical challenge, and no biomarker has been consistently validated. We aimed to assess the accuracy of three promising circulating biomarkers for diagnosing AMI—citrulline, intestinal fatty acid-binding protein (I-FABP), and D-lactate. A cross-sectional diagnostic study enrolled AMI patients admitted to the intestinal stroke center and controls with acute abdominal pain of another origin. We included 129 patients—50 AMI and 79 controls. Plasma citrulline concentrations were significantly lower in AMI patients compared to the controls [15.3 μmol/L (12.0–26.0) vs. 23.3 μmol/L (18.3–29.8), p = 0.001]. However, the area under the receiver operating curves (AUROC) for the diagnosis of AMI by Citrulline was low: 0.68 (95% confidence interval = 0.58–0.78). No statistical difference was found in plasma I-FABP and plasma D-lactate concentrations between the AMI and control groups, with an AUROC of 0.44, and 0.40, respectively. In this large cross-sectional study, citrulline, I-FABP, and D-lactate failed to differentiate patients with AMI from patients with acute abdominal pain of another origin. Further research should focus on the discovery of new biomarkers.Grants from MSD-Avenir and APHP funded the SURVIBIO study; Alexandre Nuzzo received Ph.D. Grants from “Fondation de l'Avenir” and the French Gastroenterology Society (SNFGE)

Mesure de l'affaiblissement du rayonnement X par le béryllium, le carbone et différents plastiques entre 4 et 17,5 Å

The X-ray absorption coefficients for beryllium and carbon were measured as a function of the wavelength continuously from 8 to 14 Å. The experimental values obtained are compared with various semi-empirical estimations and with the theoretical values obtained from Stobbe's formulas taking account of the screen effects. The transmission of various plastics films was measured at discrete wavelength values between 4 and 17 Å, from which semi-empirical formulas are deduced for the variation of their absorption coefficient in this range.Les coefficients d'affaiblissement du rayonnement X par le béryllium et le carbone ont été mesurés de manière continue en longueur d'onde entre 8 et 14 Å. Les valeurs expérimentales ont été comparées aux différentes estimations semi-empiriques utilisables et aux prévisions théoriques calculées à partir des formules de Stobbe, en tenant compte ou non des effets d'écran. La transmission de différentes feuilles de matières plastiques a été mesurée pour des longueurs d'onde discrètes entre 4 et 17 Å et des formules semi-empiriques de variation de leurs coefficients d'affaiblissement dans ce domaine spectral en ont été déduites

DISORDER EFFECTS ON GaP CORE LEVELS STUDIED BY ELECTRON SPECTROSCOPIES

A study by X-ray induced photoelectron and Auger electron spectroscopies of P and Ga core levels from flash-evaporated crystalline and amorphous Gap films is presented. Beside the effects of contamination the results indicate the existence of partial chemical disorder in the amorphous material