19,044 research outputs found
A HEDONIC PRICE APPROACH TO FLOOD RISK AND PROPERTY VALUE IN THE GREATER MIAMI AREA
This study investigates the relationship between property value and flood risk in Miami-Dade County Florida. Miami-Dade County has gained a lot of attention in the media for its high risk of catastrophic flooding. As climate change predictions have grown more severe, flood risk is a factor property buyers may want to consider.
This study uses hedonic pricing to see if the flood risk in the county affects the price of the home. In Miami-Dade County, properties near a public beach are considered desirable. This paper specifically looks at the interaction between distance from the beach and flood risk. This paper found Low flood risk homes have significantly lower prices than high flood risk homes if they are close to the beach (less than 45 miles), but have significantly higher prices than high risk homes that are far from the beach (at least 45 miles away). Specifically, when a home is that far away from the water, being flood safe adds a positive value to a property by around 14%. Similarly, being in a high flood risk (FEMA AE) has a positive marginal effect on the price of a home if it is close enough to a public beach
Selection and stabilization of endocytic sites by Ede1, a yeast functional homologue of human Eps15.
During clathrin-mediated endocytosis (CME), endocytic-site maturation can be divided into two stages corresponding to the arrival of the early and late proteins at the plasma membrane. The early proteins are required to capture cargo and position the late machinery, which includes proteins involved in actin assembly and membrane scission. However, the mechanism by which early-arriving proteins select and stabilize endocytic sites is not known. Ede1, one of the earliest proteins recruited to endocytic sites, facilitates site initiation and stabilization. Deletion of EDE1 results in fewer CME initiations and defects in the timing of vesicle maturation. Here we made truncation mutants of Ede1 to better understand how different domains contribute to its recruitment to CME sites, site selection, and site maturation. We found that the minimal domains required for efficient Ede1 localization at CME sites are the third EH domain, the proline-rich region, and the coiled-coil region. We also found that many strains expressing ede1 truncations could support a normal rate of site initiation but still had defects in site-maturation timing, indicating separation of Ede1 functions. When expressed in yeast, human Eps15 localized to the plasma membrane, where it recruited late-phase CME proteins and supported productive endocytosis, identifying it as an Ede1 functional homologue
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