10 research outputs found

    Investigation of Corrosion Inhibitors by Nuclear Quadrupole Resonance Relaxometry Method

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    The changes taking place with the corrosion-resistant coating, but not the state of the surface subjected to corrosion are investigated in this paper in contrast to traditional approaches. We used the method of nitrogen relaxometry NQR and multi-exponential inversion of decay of longitudinal and transverse components of the nuclear magnetization is applied for the first time for this purpose. The results of experimental studies of changes in the distributions of spin-spin and spin-lattice relaxation of crystallite powder of sodium nitrite and urotropin, the mixture of which is used as a corrosion inhibitor of ferrous metals are considered

    Resonance phenomena in photonic and magnonic crystals of multiferroics as part of thin-film fractal structures

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    The paper examines nonlinear phenomena and effects in photonic and magnonic crystals of multiferroics being part of thin-film structures under exposure of external magnetic fields. The results of the fractal crystal modeling are analyzed. It is shown that for controllable smart coverings it is possible to employ the principle of reconfiguration of fractal antenna arrays with electronic commutation of subarrays. Development of a new element base on the basis of fractal photon and magnon crystals allows creating the newest devices of data processing and transmission

    A comprehensive anticancer molecular study for genistein the promising anticancer drug

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    Objective Genistein a potent isoflavonoid isolated from dietary soybean with a wide range of biological and therapeutic activities, particularly, in cancer prevention. The molecular mechanism that explains this powerful chemopreventive activity is still not fully understood. The study designed to give a clear and complete picture about this mechanism using a flow cytometry analysis and a quantitative real-time PCR to investigate 16 gene families for 1023 genes. Methods Human cervical cancer cells were treated with genistein IC 50 for 48 h. Cell-cycle arrest and apoptosis induction were investigated using flow cytometry analysis. The high-throughput quantitative PCR array was used to explore the up- and down-regulated genes affected by the treatment. Results The quantitative real-time PCR analysis demonstrated the up- and down-regulation to 11 cancer-related gene families due to genistein treatment. Most of the up- and down-regulated genes have a role in cell proliferation, DNA replication and cell cycle progress. These findings were in harmony with the flow cytometry analysis in which a significant increase was manifested in the apoptotic cells (P < 0.05) of the treated cell cultures (18.34%) when compared with untreated cell cultures (5.7%). Conclusion The results highly pointed on the importance of genistein as promising anticancer drug. A comprehensive map regarding the anticancer molecular mechanism of this natural compound was given and many new therapeutic targets to control cancer development were uncovered. Keywords genistein, anticancer, cervical cancer, flavonoid

    Chelating Sorbents in Analytical Chemistry

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