The Review of Anthrax Situation 2013, the Forecast for 2014

The analysis of epidemiological and epizootiological situation on anthrax in the Russian Federation and in the world in 2013 is carried out. The forecast of disease for 2014 is presented. Anthrax morbidity in humans in Russia is shown to decrease in 2013 in comparison with that in 2012 (2 cases versus 12). Three anthrax cases are registered in cattle

Results of external quality control study in flow cytometric acute lymphoblastic leukemia diagnostics

Comparison of interpretation of acute lymphoblastic leukemia (ALL) flow cytometric diagnostics data was the aim of the study. Immunophenotyping data obtained from 10 patients with ALL were analysed separately in 26 laboratories from Russian Federation and Kazahstan. Results comparison showed four main type of discordance: B-lineage ALL diagnostics during heavy bone marrow regeneration, great variability of T-ALL interpretation, complexity of ambiguous lineage acute leukemia and, finally, very different report types, unique for each laboratory. All these problems are the serious obstacles for standardization of flow cytometric ALL diagnostics in multicenter setting. Continuation of similar QC rounds following by consecutive discussions with further development of consensus diagnostic algorithm could be the first step for standardization of ALL immunophenotyping in Russian Federation and CIS countries