HEMOBLASTOSIS IN CHILDREN: DIFFICULTIES IN DIAGNOSIS

Hemoblastosis are the most common malignant neoplasm in children, occupying the first place in the structure of morbidity.  The limited number of primary patients detected annually, and the atypical course of the diseases of this group make it very difficult   to diagnose at the early stages by primary care physicians – district pediatricians. As a consequence, leukemia occupies the first place  in the structure of infant mortality from malignant neoplasms. The article describes a series of clinical observations of patients with  hemoblastoses (leukemias and lymphomas), which illustrate the complexity of diagnosing diseases of this group

Case of congenital Langerhans cells histiocytosis in an infant

In this article a rare case of monosystem form of congenital Langerhans cells histiocytosis (LCH) in 3 weeks of age girl was described. Local lesion of oral mucosa of the infant with LCH was first described. Morphological, immunological and clinical features of this rare disease have been characterized. Authors concluded that timely diagnostics is very important to risk-adapted therapy at children with LCH.</p