Hepatitis C virus and non-Hodgkin's lymphomas: Meta-analysis of epidemiology data and therapy options.

Hepatitis C virus (HCV) is a global health problem affecting a large fraction of the world\u2019s population: This virus is able to determine both hepatic and extrahepatic diseases. Mixed cryoglobulinemia, a B-cell \u201cbenign\u201d lymphoproliferative disorders, represents the most closely related as well as the most investigated HCV-related extrahepatic disorder. Since this virus is able to determine extrahepatic [non-Hodgkin\u2019s lymphoma (NHL)] as well as hepatic malignancies (hepatocellular carcinoma), HCV has been included among human cancer viruses. The most common histological types of HCV-associated NHL are the marginal zone, the lymphoplasmacytic and diffuse large cell lymphomas. The role of the HCV in the pathogenesis of the B-cell lymphoproliferative disorders is confirmed also by the responsiveness of the NHL to antiviral therapy. The purpose of this review is to provide an overview of the recent literature and a meta analysis of the epidemiology data, to explain the role of HCV in the development of NHL\u2019s lymphoma. Furthermore, the possibility to treat these HCV-related NHL with the antiviral therapy or with other therapeutic options, like chemotherapy, is also discussed

A patrimonialização do kochkäse como uma perspectiva de desenvolvimento regional no médio Vale do Itajaí (SC) – UNIEDU / The patrimonialization of the kochkäse as a perspective of regional development in the middle Itajaí Valley (SC) – UNIEDU

O presente trabalho traz uma narrativa dos acontecimentos que envolveram a busca da patrimonialização do Kochkäse produzido pelos agricultores do Vale do Itajaí-SC. Para tanto, as autoras buscam enfatizar as dificuldades encontradas para que o objetivo seja alcançado. Fez-se uma reflexão dos argumentos que fundamentam o reconhecimento do Patrimônio Cultural de Natureza Imaterial do kochkäse, entre eles estão a identificação dos Sistemas Agroalimentares Locais

Taxonomy based on science is necessary for global conservation

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