Effect of Music Therapy on Anxiety among Patients Undergoing Cardiac Catheterization at Selected Hospital, Coimbatore

Music is believed to act as a stimulus distracting and diverting feelings of anxiety, stress, and fear thereby promoting relaxation. The main aim of the study was to assess the effect of Music therapy on anxiety among patients undergoing cardiac catheterization at selected hospital, Coimbatore. Pre experimental, non- equivalent posttest only control group design was used in the present study. The data was collected for a period of four weeks. By using purposive sampling technique 60 samples were selected, and 30 were assigned to the experimental group and control group respectively. The demographic profile was collected from the patients undergoing cardiac catheterization. A non-lyrical, veena based instrumental music composed in the raga hamsadvani and dwijavanti was administered to the patients in the experimental group for 30 minutes prior to the cardiac catheterization. Routine treatment was provided to the patients in the control group. 30 minutes after the intervention the level of anxiety among patients undergoing cardiac catheterization was assessed using the state trait anxiety inventory in both the groups. The calculated mean level of Anxiety and standard deviation in the experimental and control group were 75.9 and 118.26, 7.16 and 8.04 respectively. The mean difference was 42.3. The calculated ‘t’ value 22.41 was greater than the table value 3.29 at 0.001 level of significance. Hence, it was concluded that music therapy is an effective therapeutic intervention in reducing the level of anxiety among patients undergoing cardiac catheterization

IMMUNOHISTOCHEMICAL EXPRESSION OF C-KIT IN ORAL SQUAMOUS CELL CARCINOMA PATIENTS IN SOUTH INDIAN POPULATIONS

Objective: The study was designed to evaluate the C-Kit expression and also to assess the relationship with various clinicopathological characteristics in oral squamous cell carcinoma (OSCC) patients.Methods: A total number of 102 formalin-fixed paraffin-embedded retrospective tissue samples were collected, in which (n =84) were histologically confirmed for OSCC, oral epithelial dysplasia (OED) (n=9), and control group (n=10) and studied immunohistochemically. The baseline characters and the correlation between the protein expression and clinicopathological parameters were analyzed. The survival analysis was performed using Kaplan-Meier Survival Method.Results: OSCC exhibited C-Kit protein expression positivity of 6% and OED with 11.11% with no expression of this protein in control patients. Overall survival analysis showed that patients with negative expression had a better survival than patients with positive expression. However, we found that expression pattern of C-kit did not correlate with various clinicopathological characteristics.Conclusion: Vast amount of study has to be still performed to under the mechanism of OSCC in C-KIT Expression to enhance the prognosis of OSCC patients in the near future

EVALUATION OF SERUM TOLL-LIKE RECEPTOR 4 AND NUCLEAR FACTOR-ΚBP65 PROTEINS IN ORAL SQUAMOUS CELL CARCINOMA

Objective: The present study is aimed to estimate the serum toll-like receptor 4 (sTLR 4) and nuclear factor-κB (NF-κB) p65 proteins in patients of oral squamous cell carcinoma (OSCC). Methods: The study was performed in prospective cases of 22 OSCC patients, 10 oral epithelial dysplasia patients, 8 control with chewing habits, and 4 control patients. The estimation of sTLR 4 and NF-κBp65 proteins was done by enzyme-linked immunosorbent assay method. The Pearson correlation test was performed to find out the relationship between these two proteins. Results: There was an increase in the sTLR 4 protein level in study groups OSCC, oral premalignant disorders, control with chewing habits, and control habits such as 1.31 ng/ml±1.06 ng/ml, 1.99 ng/ml±0.98 ng/ml, and 2.11 ng/ml±0.61 ng/ml, respectively, when comparable (p=0.008) to control patients with 0.60 ng/ml±0.24 ng/ml. However, in the case of serum level NF-κBp65 protein all the study groups including the control showed same values. The Pearson correlation test showed significant relationship (rpearson=0.91, [p<0.0005]) of these two proteins only in the OSCC patients. Conclusion: It can be concluded that serum levels of TLR 4 are increased in OSCC patients, but there was no variation seen for the NF-κBp65 protein. There is a strong interrelationship exist between the serum levels of TLR 4 and NF-κBp65 proteins in the OSCC patients only

Where Am I in Wi-Fi?-An Experimental study

Abstract: Location identification is an essential area of study in ubiquitous computing. The IEEE 802.11 Wi-Fi network is the pioneer in the arena of short range wireless systems and its utility is observed in many domains. This paper elegantly depicts the idea of a localization technique intertwined in Wi-Fi network to facilitate roaming of wireless nodes. The RSSI measurement is carried out with respect to the APs and rules are demarcated for the initial condition. A data base is created and streamlined with the existing rules and rank entries and location is assessed for a specific node of interest. This report expounds the results observed in an Engineering institution where approximately 500 APs are mounted around the campus. The context parameter observed is the location of a client with average signal strength of 75mV