Basic principles of building of E-network model of a complex technical system

Methodological bases of building of dynamic models of hybrid systems using principles of a «block» modelling are exposed on the basis of the E-network formalism. The presented methods are based on use of mechanisms of hierarchical interaction of dynamic model elements. Principles of organization of E-network hierarchical circuits with use of rigid and flexible structures are shown. The mechanism of interaction of static and dynamic components is specified

Prehistory of Volgograd State University. 1971–1980

Introduction. The authors analyze the process of establishing a state university in Volgograd, the last university set up in the RSFSR during the existence of the USSR. Materials. This study is based on the basis of archival materials first introduced into scientific use (State Archive of the Russian Federation (SARF), Russian State Archive of Recent History (RSARH), Center of Recent History Documentation of Volgograd Region (CRHDVO)). Analysis and Results. The initial idea of the representatives of governing bodies in Volgograd region to organize a university on the basis of Volgograd Polytechnic Institute did not find support from the leadership of the country in 1971. In 1972 it was decided to start organizing a new type of higher education institution for Volgograd, that is a classic university. This idea found support in Moscow, which was manifested in the resolutions of the Secretariat of the CPSU Central Committee in 1973 and the USSR Council of Ministers and the RSFSR Council of Ministers in 1974. The necessity for creating appropriate educational and teaching resources and facilities, the manpower problem and insufficient funds led to postponing initially proposed dates for the University opening from 1974 to 1978, and then to 1980. The first admission of students in 1980 was in the building of a comprehensive school specially built for this purpose near the future University complex, the first building of which would be put into service only in 1983. The issue of the development of the young University was under the constant control of the Council of Ministers of the RSFSR for many years. Only in March 1986 it was decided to discontinue supervision over the resolution of the Council of Ministers of the RSFSR no. 561 of October 21, 1974

Computer Simulation of a Plasma Vibrator Antenna

The use of new plasma technologies in antenna technology is widely discussed nowadays. The plasma antenna must receive and transmit signals in the frequency range of a transceiver. Many experiments have been carried out with plasma antennas to transmit and receive signals. Due to lack of experimental data and because experiments are difficult to carry out, there is a need for computer (numerical) modeling to calculate the parameters and characteristics of antennas, and to verify the parameters for future studies. Our study has modeled plasma vibrator (dipole) antennas (PDA) and metal vibrator (dipole) antennas (MDA), and has calculated the characteristics of PDAs and MDAs in the full KARAT electro-code. The correctness of the modeling has been tested by calculating a metal antenna using the MMANA program

Selfoscillations of Suspended Carbon Nanotubes with a Deflection Sensitive Resistance under Voltage Bias

We theoretically investigate the electro-mechanics of a Suspended Carbon Nanotube with a Deflection Sensitive Resistance subjected to a homogeneous Magnetic Field and a constant Voltage Bias. We show that, (with the exception of a singular case), for a sufficiently high magnetic field the time-independent state of charge transport through the nanotube becomes unstable to selfexcitations of the mechanical vibration accompanied by oscialltions in the voltage drop and current across the nanotube.Comment: 4 pages, 1 figur

IN VITRO EXPERIMENTAL REWIRING OF 4 NEUTROPHILIC GRANULOCYTE SUBSETS FROM THE PRO-INFLAMMATORY TO THE ANTI-INFLAMMATORY PHENOTYPE IN CHILDREN WITH SURGICAL PURULENT INFECTION OF SOFT TISSUE

Treatment of young children with atypical or recurrent purulent soft tissue infections (PSTD) that do not respond well to surgery and antibiotics is most challenging. PSTD occurs against the background of impaired functioning of the immune system and, first of all, the system of neutrophilic granulocytes (NG). The vector effect of immunotropic therapy on a specific NG subsets may allow the correction of NG dysfunctions without compromising host protection, including strategies to enhance, inhibit or restore their functions.The aim of study: to evaluate in vitro the modulating effects of arginyl-alpha-aspartyl-lysyl-valyl-tyrosyl-arginine (HP) on the transformed phenotype of 4 NG subsets, as well as on the functional activity of NG in children with purulent-inflammatory soft tissue diseases.We studied samples of peripheral blood (PB) from young children 2-4 years old: 17 children with atypical acute PSTD and 10 apparently healthy children. At stage I, a comparative assessment of the content and phenotype of 4 NG subsets CD16+CD62L+СD63- , CD16+CD62L+СD63+, СD64- CD16+CD32+CD11b+, СD64+CD16+CD32+CD11b+, phagocytic and microbicidal functions of NG was carried out. At stage II, the in vitro system determined the effects of HP on NG in children with PSTD according to the studied parameters. By the method of flow cytometry (FC500 “Beckman Coulter” (USA), conjugates of MkAT “Beckman Coulter International S.A.” (France)), the relative number of NGs of the studied subsets and the density of receptor expression (MFI) were determined. To assess the phagocytic function of NG a microbiological method was used to assess the completeness of phagocytosis with S. aureus (strain 209). The activity of NG NADPH oxidase was investigated in the NBT-spontaneous test (NBTsp.) and in the in vitro NBT-induced test (NBTind.). A comparative study of PB samples from conventionally healthy children and children with PSTD made it possible to identify various variants of transformation of the phenotype of the studied NG subsets, associated with defects in their functional activity. In the in vitro system the effects of HP were demonstrated, manifested by a decrease in the amount of CD16+CD62L+CD63+NG and an increase in CD16+CD62L+CD63- NG, modulation of the negatively altered phenotype of subsets CD64- CD32+CD16+CD11b+NG and CD64+CD32+CD16+CD11b+NG, aimed at restoring phagocytic function and maintaining the tension of NADPH oxidases.As a result of the study it was found the immunomodulatory effects of HP, which is manifested in the reorientation of NG from the pro-inflammatory phenotype to the anti-inflammatory one, which can be used in the future when creating personalized targeted immunotherapy aimed at correcting defective functioning NG in early children, suffering from PSTD