23 research outputs found
Theoretical and practical approaches to the formation of equity for the development of entrepreneurial activity
The article is devoted to the methodology of formation and optimization of the company's equity. In a market economy, the financial stability of the firm, depending on the financial condition, is one of the most important factors in the life of the firm and the development of entrepreneurial activity. A positive financial condition determines the competitiveness of the company in the market. It also helps in cooperation with creditors in the financial aspect. The financial condition demonstrates the ability of the organization to Finance activities with its own funds, as well as to manage them rationally in relations with other persons. Therefore, the goal of any company – to maintain a stable, stable financial condition and profit. The most important for the development of the company is the formation and increase of equity capital. The article deals with various methodological approaches to the formation of the company's equity. The traditional position of equity formation and its optimization is found in accounting, as well as in the special economic literature. However, in the study of different approaches to determining the final result of financial and economic activities of the company, such interpretation raises serious objections. The initial stage of capital formation management of the company is to determine the need for the required amount. Optimization of the total capital requirement of the company is achieved by various methods, which eventually allow to achieve a positive result of the company. The article focuses on the areas in the field of ensuring the adoption of operational management decisions on the choice of sources of financing of economic activities of firms from the position of ensuring a sufficient level of solvency and improving the efficiency of capital use. The main stages of the optimization process of the capital of the company
CERVICAL MUCUS NEUTROPHILS FUNCTIONAL STATUS INTERACTION WITH THE SPECIES COMPOSITION OF VAGINAL LACTOBACILLI IN PREGNANT WOMEN
Aim. Of the study is to assess cervical mucus neutrophils functional status depend on dominant lactobacillus strain in I trimester of pregnancy women. Material and methods. We definded 40 lactobacillus strains obtained from the genital tract of the pregnant women. We used mass spectrometry analysis to identify vaginal lactobacilli and evaluated biofilm formation. Also, we studied cervical mucus neutrophils viability, lysosomal activity, spontaneous and induced NBT test (Nitroblue Tetrazolium test), ability to absorb the latex particles. Isolated strains were divided into 3 groups depending on presence or absence of vaginal or cervical channel infectious diseases. Results. We identified 5 lactobacilli types: L. jensenii, L. mspatus, L. аcidophilus, L. gasseri, L. delbrueckii among 40 definded strains. We determined different intensity of phagocytosis depending on dominant strain in normocenosis. With the L. crispatus prevalence demonstrated the least intensity of phagocytosis compared with L. acidophilus and L.jensenii. Lactobacilli able to intensively produce biomatrix in condition of genital infection. Thus blocking antigenic potential and result in absence of NBT-reducing power of neutrophilic granulocytes and reduction antimicrobial protection of pregnant women genital tract mucosa. Conclusion. The indicators of neutrophils functional status depend on dominant lactobacilli strain in I trimester of pregnancy women