The Metallicity Dependence of the Fourier Components of RR Lyrae Light Curves is the Oosterhoff/Arp/Preston Period Ratio Effect in Disguise

The correlation of particular Fourier components of the light curves of RR Lyrae variables with metallicity, discovered by Simon and later by Kovacs and his coworkers, is shown to have the same explanation as the period ratios (period shifts in log P) between RRab Lyrae variables that have the same colors, amplitudes, and light-curve shapes but different metallicities. A purpose of this paper is to demonstrate that the model which predicts the period-metallicity relations is the mediating parameters of colors, amplitudes, and light-curve shapes also explains the Simon/Kovacs et al. correlation between period, Phi_31, and metallicity. The proof is made by demonstrating that the combination of the first and third phase terms in a Fourier decomposition of RRab light curves, called Phi_31 by Simon and Lee, varies monotonically across the RR Lyrae instability strip in the same way that amplitude, color, and rise time vary with period within the strip. The premise of the model is that if horizontal branches at the RR Lyrae strip are stacked in luminosity according to the metallicity, then there necessarily must be a log period shift between RR Lyraes with different metallicities at the same Phi_31 values. However, there are exceptions to the model. (...)Comment: 17 pages, 8 figures, 1 table. Accepted for publication in The A

Lactobacillus fermentum (PCC®) supplementation and gastrointestinal and respiratory-tract illness symptoms: a randomised control trial in athletes

BACKGROUND Probiotics purportedly reduce symptoms of gastrointestinal and upper respiratory-tract illness by modulating commensal microflora. Preventing and reducing symptoms of respiratory and gastrointestinal illness are the primary reason that dietary supplementation with probiotics are becoming increasingly popular with healthy active individuals. There is a paucity of data regarding the effectiveness of probiotics in this cohort. The aim of this study was to evaluate the effectiveness of a probiotic on faecal microbiology, self-reported illness symptoms and immunity in healthy well trained individuals. METHODS Competitive cyclists (64 males and 35 females; age 35 ± 9 and 36 ± 9 y, VO2max 56 ± 6 and 52 ± 6 ml.kg-1.min-1, mean ± SD) were randomised to either probiotic (minimum 1 × 109 Lactobacillus fermentum (PCC®) per day) or placebo treatment for 11 weeks in a double-blind, randomised, controlled trial. The outcome measures were faecal L. fermentum counts, self-reported symptoms of illness and serum cytokines. RESULTS Lactobacillus numbers increased 7.7-fold (90% confidence limits 2.1- to 28-fold) more in males on the probiotic, while there was an unclear 2.2-fold (0.2- to 18-fold) increase in females taking the probiotic. The number and duration of mild gastrointestinal symptoms were ~2-fold greater in the probiotic group. However, there was a substantial 0.7 (0.2 to 1.2) of a scale step reduction in the severity of gastrointestinal illness at the mean training load in males, which became more pronounced as training load increased. The load (duration×severity) of lower respiratory illness symptoms was less by a factor of 0.31 (99%CI; 0.07 to 0.96) in males taking the probiotic compared with placebo but increased by a factor of 2.2 (0.41 to 27) in females. Differences in use of cold and flu medication mirrored these symptoms. The observed effects on URTI had too much uncertainty for a decisive outcome. There were clear reductions in the magnitude of acute exercise-induced changes in some cytokines. CONCLUSION L. fermentum may be a useful nutritional adjunct for healthy exercising males. However, uncertainty in the effects of supplementation on URTI and on symptoms in females needs to be resolved. TRIAL REGISTRATION The trial was registered in the Australia and New Zealand Clinical Trials Registry (ACTRN12611000006943).The study was funded by Christian Hansen A/S, Probiomics and the Australian Institute of Sport

Cherenkov radio pulses from electromagnetic showers in the time-domain

The electric field of the Cherenkov radio pulse produced by a single charged particle track in a dielectric medium is derived from first principles. An algorithm is developed to obtain the pulse in the time domain for numerical calculations. The algorithm is implemented in a Monte Carlo simulation of electromagnetic showers in dense media (specifically designed for coherent radio emission applications) as might be induced by interactions of ultra-high energy neutrinos. The coherent Cherenkov radio emission produced by such showers is obtained simultaneously both in the time and frequency domains. A consistency check performed by Fourier-transforming the pulse in time and comparing it to the frequency spectrum obtained directly in the simulations yields, as expected, fully consistent results. The reversal of the time structure inside the Cherenkov cone and the signs of the corresponding pulses are addressed in detail. The results, besides testing algorithms used for reference calculations in the frequency domain, shed new light into the properties of the radio pulse in the time domain. The shape of the pulse in the time domain is directly related to the depth development of the excess charge in the shower and its width to the observation angle with respect to the Cherenkov direction. This information can be of great practical importance for interpreting actual data.Comment: 10 pages, 4 figure

Theory of Diluted Magnetic Semiconductor Ferromagnetism

We present a theory of carrier-induced ferromagnetism in diluted magnetic semiconductors (III_{1-x} Mn_x V) which allows for arbitrary itinerant-carrier spin polarization and dynamic correlations. Both ingredients are essential in identifying the system's elementary excitations and describing their properties. We find a branch of collective modes, in addition to the spin waves and Stoner continuum which occur in metallic ferromagnets, and predict that the low-temperature spin stiffness is independent of the strength of the exchange coupling between magnetic ions and itinerant carriers. We discuss the temperature dependence of the magnetization and the heat capacity

Isotropy of the velocity of light and the Sagnac effect

In this paper, it is shown, using a geometrical approach, the isotropy of the velocity of light measured in a rotating frame in Minkowski space-time, and it is verified that this result is compatible with the Sagnac effect. Furthermore, we find that this problem can be reduced to the solution of geodesic triangles in a Minkowskian cylinder. A relationship between the problems established on the cylinder and on the Minkowskian plane is obtained through a local isometry.Comment: LaTeX, 13 pages, 3 eps figures; typos corrected, added references, minor changes; to appear in "Relativity in Rotating Frames", ed. G. Rizzi G. and M.L. Ruggiero, Kluwer Academic Publishers, Dordrecht (2003

Cephalosporin-3’-diazeniumdiolate NO-donor prodrug PYRRO-C3D enhances azithromycin susceptibility of non-typeable Haemophilus influenzae biofilms

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Objectives: PYRRO-C3D is a cephalosporin-3-diazeniumdiolate nitric oxide (NO)-donor prodrug designed to selectively deliver NO to bacterial infection sites. The objective of this study was to assess the activity of PYRRO-C3D against non-typeable Haemophilus influenzae (NTHi) biofilms and examine the role of NO in reducing biofilm-associated antibiotic tolerance. Methods: The activity of PYRRO-C3D on in vitro NTHi biofilms was assessed through CFU enumeration and confocal microscopy. NO release measurements were performed using an ISO-NO probe. NTHi biofilms grown on primary ciliated respiratory epithelia at an air-liquid interface were used to investigate the effects of PYRRO-C3D in the presence of host tissue. Label-free LC/MS proteomic analyses were performed to identify differentially expressed proteins following NO treatment. Results: PYRRO-C3D specifically released NO in the presence of NTHi, while no evidence of spontaneous NO release was observed when the compound was exposed to primary epithelial cells. NTHi lacking β-lactamase activity failed to trigger NO release. Treatment significantly increased the susceptibility of in vitro NTHi biofilms to azithromycin, causing a log-fold reduction in viability (p<0.05) relative to azithromycin alone. The response was more pronounced for biofilms grown on primary respiratory epithelia, where a 2-log reduction was observed (p<0.01). Label-free proteomics showed that NO increased expression of sixteen proteins involved in metabolic and transcriptional/translational functions. Conclusions: NO release from PYRRO-C3D enhances the efficacy of azithromycin against NTHi biofilms, putatively via modulation of NTHi metabolic activity. Adjunctive therapy with NO mediated through PYRRO-C3D represents a promising approach for reducing biofilm associated antibiotic tolerance

The Amplitude of Non-Equilibrium Quantum Interference in Metallic Mesoscopic Systems

We study the influence of a DC bias voltage V on quantum interference corrections to the measured differential conductance in metallic mesoscopic wires and rings. The amplitude of both universal conductance fluctuations (UCF) and Aharonov-Bohm effect (ABE) is enhanced several times for voltages larger than the Thouless energy. The enhancement persists even in the presence of inelastic electron-electron scattering up to V ~ 1 mV. For larger voltages electron-phonon collisions lead to the amplitude decaying as a power law for the UCF and exponentially for the ABE. We obtain good agreement of the experimental data with a model which takes into account the decrease of the electron phase-coherence length due to electron-electron and electron-phonon scattering.Comment: New title, refined analysis. 7 pages, 3 figures, to be published in Europhysics Letter

Two-dimensional gapless spin liquids in frustrated SU(N) quantum magnets

A class of the symmetrically frustrated SU(N) models is constructed for quantum magnets based on the generators of SU(N) group. The total Hamiltonian lacks SU(N) symmtry. A mean field theory in the quasi-particle representation is developed for spin liquid states. Numerical solutions in two dimension indicate that the ground states are gapless and the quasi-particles are Dirac particles. The mechanism may be helpful in exploring the spin liquid phases in the spin-1 bilinear-biquadratic model and the spin-orbital model in higher dimensions.Comment: 9 pages, 3 figures, to appear in New Journal of Physic

Solutions for correlations along the coexistence curve and at the critical point of a kagom\'e lattice gas with three-particle interactions

We consider a two-dimensional (d=2) kagom\'e lattice gas model with attractive three-particle interactions around each triangular face of the kagom\'e lattice. Exact solutions are obtained for multiparticle correlations along the liquid and vapor branches of the coexistence curve and at criticality. The correlation solutions are also determined along the continuation of the curvilinear diameter of the coexistence region into the disordered fluid region. The method generates a linear algebraic system of correlation identities with coefficients dependent only upon the interaction parameter. Using a priori knowledge of pertinent solutions for the density and elementary triplet correlation, one finds a closed and linearly independent set of correlation identities defined upon a spatially compact nine-site cluster of the kagom\'e lattice. Resulting exact solution curves of the correlations are plotted and discussed as functions of the temperature, and are compared with corresponding results in a traditional kagom\'e lattice gas having nearest-neighbor pair interactions. An example of application for the multiparticle correlations is demonstrated in cavitation theory