Dental-alveolar Compensatory Phenomena of Malocclusion Class II Angle. Lateral Cephalometric Study

The purpose of our study was to identify the dental-alveolar phenomena making up for skeletal imbalances due to malocclusion Class II, using the lateral cephalometry method. The research was carried out on 52 patients (29 girls and 23 boys), aged between 7 and 18 years, chosen from 113 cases clinically diagnosed with malocclusion Class II Angle. The lateral cephalometrie images were processed using the ORTHALIS software, whereas the cephalometric measurements were conducted by means of the Tweed and Steiner method. The databases and statistical analyses were carried out using the SPSS 16.0 software for Windows and descriptive statistics means. The results obtained reveal 5 skeletal patterns of Class II. The dental-alveolar compensation phenomena occurring in the Class II skeletal patterns associated with the skeletal growing patterns identified in the study group took a wide variety of dental-alveolar forms. The wide variety of clinical manifestations and expressions at the skeletal and dental-alveolar levels fully supports the opinion according to which malocclusions Class II Angle are far from being a mere clinical entity, but rather a complex craniodental-maxillo-facial syndrom

Liposome loaded chitosan hydrogels, a promising way to reduce the burst effect in drug release a comparativ analysis

International audienceIn order to analyze the effect induced by encapsulating the drug in liposomes, comparative studies were performed for control hydrogels and complex systems (the same hydrogels containing liposomes). The results showed that the use of liposomes entrapped within chitosan hydrogels allows a strong decrease of burst effect and, moreover, the mechanism of drug release is a complex Fickian diffusion, consisting of drug diffusion through the swollen hydrogel and/or water filled pores, being continuously fed by calcein loaded in liposomes