Benefits of demand-side response in providing frequency response service in the future GB power system

The demand for ancillary service is expected to increase significantly in the future Great Britain (GB) electricity system due to high penetration of wind. In particular, the need for frequency response, required to deal with sudden frequency drops following a loss of generator, will increase because of the limited inertia capability of wind plants. This paper quantifies the requirements for primary frequency response and analyses the benefits of frequency response provision from demand-side response (DSR). The results show dramatic changes in frequency response requirements driven by high penetration of wind. Case studies carried out by using an advanced stochastic generation scheduling model suggest that the provision of frequency response from DSR could greatly reduce the system operation cost, wind curtailment, and carbon emissions in the future GB system characterized by high penetration of wind. Furthermore, the results demonstrate that the benefit of DSR shows significant diurnal and seasonal variation, whereas an even more rapid (instant) delivery of frequency response from DSR could provide significant additional value. Our studies also indicate that the competing technologies to DSR, namely battery storage, and more flexible generation could potentially reduce its value by up to 35%, still leaving significant room to deploy DSR as frequency response provider

Minimum Manhattan Distance Approach to Multiple Criteria Decision Making in Multiobjective Optimization Problems

A minimum Manhattan distance (MMD) approach to multiple criteria decision making in multiobjective optimization problems (MOPs) is proposed. The approach selects the final solution corresponding with a vector that has the MMD from a normalized ideal vector. This procedure is equivalent to the knee selection described by a divide and conquer approach that involves iterations of pairwise comparisons. Being able to systematically assign weighting coefficients to multiple criteria, the MMD approach is equivalent to a weighted-sum (WS) approach. Because of the equivalence, the MMD approach possesses rich geometric interpretations that are considered essential in the field of evolutionary computation. The MMD approach is elegant because all evaluations can be performed by efficient matrix calculations without iterations of comparisons. While the WS approach may encounter an indeterminate situation in which a few solutions yield almost the same WS, the MMD approach is able to determine the final solution discriminately. Since existing multiobjective evolutionary algorithms aim for a posteriori decision making, i.e., determining the final solution after a set of Pareto optimal solutions is available, the proposed MMD approach can be combined with them to form a powerful solution method of solving MOPs. Furthermore, the approach enables scalable definitions of the knee and knee solutions.Comment: 14 pages, 9 figure

A Supernova Factory in the Merger System Arp 299

We have imaged the nearby galaxy merger Arp 299 at arcsecond and milliarcsecond resolution, using both the Very Large Array and the Very Long Baseline Array. The large-scale radio emission from the merger contains 5 bright, compact radio sources embedded in diffuse emission, with diameters less than 200 pc. Supernova rates of 0.1 to 1 per year are required to produce the VLA-detected radio emission in these sources. Two of the compact VLA radio sources, designated Source A and Source D, also have been detected and imaged at milliarcsecond scales. Source A, which is associated with the nucleus of one of the merging galaxies, contains five milliarcsecond-scale sources, each with a radio power between 100 and 1000 times that of the Galactic supernova remnant Cassiopeia A. Four of these have flat or inverted spectra and appear to be young supernovae. Three of the VLBI-scale sources are located within 10 pc (projected) of one another, and two are separated by less than 3 pc, indicating that they all may be within the same super starcluster or complex of such clusters. The brightest VLBI-scale source, A0, has an extremely inverted pectrum, with alpha larger than +2 at gigahertz frequencies. It seems to be the youngest supernova, which has not yet broken out of its circumstellar shell. The milliarcsecond radio sources within Source A appear to constitute a upernova factory, confirming the presence of an extreme starburst that peaked at least a few million years ago.Comment: Accepted for the Astrophysical Journal, 22 pages, 10 figure

Value of thermostatic loads in future low-carbon Great Britain system

This paper quantifies the value of a large population of heterogeneous thermostatically controlled loads (TCLs). The TCL dynamics are regulated by means of an advanced demand side response model (DSRM). It optimally determines the flexible energy/power consumption and simultaneously allocates multiple ancillary services. This model explicitly incorporates the control of dynamics of the TCL recovery pattern after the provision of the selected services. The proposed framework is integrated in a mixed integer linear programming formulation for a multi-stage stochastic unit commitment. The scheduling routine considers inertia-dependent frequency response requirements to deal with the drastic reduction of system inertia under future low-carbon scenarios. Case studies focus on the system operation cost and CO2 emissions reductions for individual TCLs for a) different future network scenarios, b) different frequency requirements, c) changes of TCL parameters (e.g. coefficient of performance, thermal insulation etc.)

Experimental behaviour of FRP-confined large-scale curvilinearized rectangular RC columns under axial compression

Existing research has shown that strengthening through fibre-reinforced polymer (FRP) confinement is highly effective for circular columns but much less so for sTuare and rectangular columns due to the flat sides and sharp corners in the latter. Rounding the corners in the latter columns can enhance the effectiveness of confinement, but its benefit is limited. To overcome this problem, an alternative strengthening techniTue has recently been proposed by some researchers, in which the flat sides of a sTuarerectangular section are modified into slightly curved sides before FRP confinement (referred to as section curvilinearization). The resulting columns, referred to as curvilinearized sTuare rectangular columns, are much more effectively confined by an FRP jacket than the original sTuarerectangular columns with only corner rounding, and the associated column size increase is limited. While this section curvilinearization techniTue is highly attractive, there has been only very limited research on the behaviour of FRP-confined curvilinearized sTuare rectangular columns. In particular, all the existing experimental work has been limited to small-scale sTuare columns (with section widths being around or below 1 mm) under axial compression. Against the above background, a large experimental programme has been under way at The Hong Kong Polytechnic University to study the behaviour of large-scale curvilinearized RC columns under both concentric and eccentric compression. Both sTuare and rectangular columns have been considered in the experimental programme. This paper presents a systematic experimental study on the behaviour of FRP-confined curvilinearized rectangular RC columns under axial compression to study the effects of the following parameters: rise-to-span ratio of the edge profile, sectional aspect ratio and corner radius. In addition to the presentation of experimental results, two existing stress-strain models for FRP-confined concrete in these columns are assessed to reveal their limitations

Metabolism of ticagrelor in patients with acute coronary syndromes.

© The Author(s) 2018Ticagrelor is a state-of-the-art antiplatelet agent used for the treatment of patients with acute coronary syndromes (ACS). Unlike remaining oral P2Y12 receptor inhibitors ticagrelor does not require metabolic activation to exert its antiplatelet action. Still, ticagrelor is extensively metabolized by hepatic CYP3A enzymes, and AR-C124910XX is its only active metabolite. A post hoc analysis of patient-level (n = 117) pharmacokinetic data pooled from two prospective studies was performed to identify clinical characteristics affecting the degree of AR-C124910XX formation during the first six hours after 180 mg ticagrelor loading dose in the setting of ACS. Both linear and multiple regression analyses indicated that ACS patients presenting with ST-elevation myocardial infarction or suffering from diabetes mellitus are more likely to have decreased rate of ticagrelor metabolism during the acute phase of ACS. Administration of morphine during ACS was found to negatively influence transformation of ticagrelor into AR-C124910XX when assessed with linear regression analysis, but not with multiple regression analysis. On the other hand, smoking appears to increase the degree of ticagrelor transformation in ACS patients. Mechanisms underlying our findings and their clinical significance warrant further research.Peer reviewedFinal Published versio

A Storm in a "T" Cup

We revisit the process of transversification and agglomeration of particle momenta that are often performed in analyses at hadron colliders, and show that many of the existing mass-measurement variables proposed for hadron colliders are far more closely related to each other than is widely appreciated, and indeed can all be viewed as a common mass bound specialized for a variety of purposes.Comment: 3 pages, 2 figures, presented by K.C. Kong at the 19th Particles and Nuclei International Conference, PANIC 2011, MIT, Cambridge, MA (July 24-29, 2011