Prerequisites for Geostatistics on Unstructured Grids

Introduction A recent problem for geostatistics is application to populating unstructured grids, which have been under consideration for reservoir analysis for some time. One major challenge is dealing with the huge variation of scales involved across a set of unstructured grid elements. Accounting for reservoir structures, wells, and heterogeneity can result in elements ranging from less than a cubic meter to thousands of cubic meters in volume. An initial response to dealing with these scales and others describing the various sources of data was direct geostatistics -a few past CCG papers on the subject include Current practice is to generate a high resolution (fine) model on a structured grid and upscale the results to an unstructured (coarse) grid. This approach has a number of issues. The fine and coarse grids do not conform causing problems for upscaling, especially with unstructured elements smaller than the structured elements, which can occur near wells, leads to a poor representation of heterogeneity; related to the last issue, unstructured elements are all represented by varying numbers of structured elements, which may lead to a bias; and structured grids contain numerous geometrical characteristics which are suboptimal for flow based upscaling. Structured discretization is not the optimal choice. Most numerical integration schemes such as the midpoint, trapezoid, and various Gauss-quadrature rules only involve integration points within and on the boundary of a region. Therefore, the new approach involves discretization resulting in conforming grids. In general, this can only be accomplished if the discretization is also unstructured

THE ENZYMATIC STATUS FEATURES IN BLOOD LYMPHOCYTES IN CHILDREN WITH DYSFUNCTIONAL DISORDERS OF BILIARY TRACT AND THEIR ASSOCIATION WITH GIARDIASIS

N the study of NAD(P)-dependent dehydrogenases activity in blood lymphocytes in children with dysfunctional disorders of the biliary tract (DDBT) and. DDBT in association with giardiasis detected significant changes in the intracellular metabolism. In children with DDBT in blood lymphocytes the levels of substrate flow decreased at the terminal reactions of glycolysis and. the tricarboxylic acid cycle, which determines the inhibition, respectively, anaerobic and aerobic cellular respiration. It's been established that in blood lymphocytes of children with DDBT, associated with giardiasis, the activity of enzymes determining the state of aerobic respiration is reduced, while maintaining the normal level of intensity of the terminal reactions of anaerobic glycolysis. Regardless of the presence or absence of giardiasis in children with DDBT the activity of pentose phosphate cycle is reduced which characterizes the inhibition of the reactions of macromolecular synthesis

Oxidative Carbonylation of Dipropargylarylamines

The catalytic oxidative methoxycarbonylation reaction of N,N-dipropargylarylamines has been investigated. PdCl2-CuCl2 has been studied as a catalytic system. Consecutive reactions of substitutive and additive methoxycarbonylation have been going in this process, which has been complicated by dimerisation, polymerization and cyclization processes. Apparently the results of process are determined by stability of intermediate reactionary complexes with participation of catalytic system PdCl2-CuCl2. The structures of synthesized cyclic amino triesters are established by analysis of experimental spectra NMR 1H and 13C, comparison with calculated spectra of possible hypothetic structures and estimation of thermodynamics properties by Joback fragmentation and MOPAC Semi-empirical PM3 methods

FUNCTIONAL ACTIVITY OF NEUTROPHILS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA

Abstract. Functional activity of neutrophylic granulocytes from whole blood of the children with acute  lymphoblastic leukemia was tested by means of luminolnduced chemiluminescence detection. We haverevealedincreased production of reactive oxygen species under basal conditions, and a decreased chemiluminescent  response after zymosan-induced stimulation. (Med. Immunol., 2011, vol. 13, N 6, pp 631-634