1,216 research outputs found
Prospects For Identifying Dark Matter With CoGeNT
It has previously been shown that the excess of events reported by the CoGeNT
collaboration could be generated by elastically scattering dark matter
particles with a mass of approximately 5-15 GeV. This mass range is very
similar to that required to generate the annual modulation observed by
DAMA/LIBRA and the gamma rays from the region surrounding the Galactic Center
identified within the data of the Fermi Gamma Ray Space Telescope. To
confidently conclude that CoGeNT's excess is the result of dark matter,
however, further data will likely be needed. In this paper, we make projections
for the first full year of CoGeNT data, and for its planned upgrade. Not only
will this body of data more accurately constrain the spectrum of nuclear recoil
events, and corresponding dark matter parameter space, but will also make it
possible to identify seasonal variations in the rate. In particular, if the
CoGeNT excess is the product of dark matter, then one year of CoGeNT data will
likely reveal an annual modulation with a significance of 2-3. The
planned CoGeNT upgrade will not only detect such an annual modulation with high
significance, but will be capable of measuring the energy spectrum of the
modulation amplitude. These measurements will be essential to irrefutably
confirming a dark matter origin of these events.Comment: 6 pages, 6 figure
RigiditĂ© artĂ©rielle mesurĂ©e par pOpmĂštreÂź chez les patients Ă risque cardiovasculaire, lien aux plaques dâathĂ©rome carotidien
PURPOSE:
Aortic stiffness is a functional and structural consequence of ageing and arteriosclerosis. Regional arterial stiffness can be easily evaluated using pOpmetre(Âź) (Axelife SAS, France). This new technique assesses the pulse wave transit time (TT) between the finger (TTf) and the toe (TTt). Based on height chart, regional pulse wave velocity (PWV) between the toe and the finger can be estimated (PWVtf). pOpscore(Âź) index is also calculated as the ratio between PWVtoe and PWVfinger and can be considered as a peripheral vascular stiffness index. The aim of the study was to evaluate the relationship between pOpmetre(Âź) indices and the presence of carotid plaques in a population with cardiovascular risk factors.
METHODS:
In 77 consecutive patients recruited for a vascular screening for atherosclerosis (46 men aged 54 ± 2 years; 31 women aged 49 ± 3 years; ns), the difference between TTt and TTf (called Dt-f), the regional pulse wave velocity between the toe and the finger (PWVtf = constant à height/Dt-fm/s) and pOpscore(Ÿ) were measured by pOpmetre(Ÿ). Presence of carotid plaques was assessed using ultrasound imaging. The local aortic stiffness (AoStiff) was evaluated by the Physioflow(Ÿ) system.
RESULTS:
No difference was found between patients with or without carotid plaques (n=25 versus 52) for Ankle-Brachial Pressure Index (ABPI: 1.15 ± 0.04 versus 1.12 ± 0.03), nor for diastolic or systolic blood pressure (87 ± 3 versus 82 ± 2; 137 ± 3 versus 132 ± 2 mmHg). The first group was older than the second (59 ± 2 versus 49 ± 2 years, P<0.002) with a larger intimae media thickness (0.69 ± 0.02 versus 0.63 ± 0.01 mm, P<0.004), a higher AoStiff (10.4 ± 0.7 versus 8.2 ± 0.5m/s, P<0.02), and PWVtf (14.3 ± 1.0 versus 10.7 ± 0.7 m/s, P<0.004) and a shorter Dt-f (57.9 ± 5.1 versus 73.5 ± 3.5 ms, P<0.01). PWVtf (r(2)=0.49, P<0.0001) and Dt-f (r(2)=0.54, P<0.0001) correlated with age. A significant difference in pOpscore(Ÿ) index was observed between both groups (1.51 ± 0.3 versus 1.41 ± 0.2, P<0.006).
CONCLUSION:
Our results show a significant arterial stiffness indices measured by pOpmetre(Âź) in patients with and without carotid plaques
Large-Mass Ultra-Low Noise Germanium Detectors: Performance and Applications in Neutrino and Astroparticle Physics
A new type of radiation detector, a p-type modified electrode germanium
diode, is presented. The prototype displays, for the first time, a combination
of features (mass, energy threshold and background expectation) required for a
measurement of coherent neutrino-nucleus scattering in a nuclear reactor
experiment. The device hybridizes the mass and energy resolution of a
conventional HPGe coaxial gamma spectrometer with the low electronic noise and
threshold of a small x-ray semiconductor detector, also displaying an intrinsic
ability to distinguish multiple from single-site particle interactions. The
present performance of the prototype and possible further improvements are
discussed, as well as other applications for this new type of device in
neutrino and astroparticle physics (double-beta decay, neutrino magnetic moment
and WIMP searches).Comment: submitted to Phys. Rev.
MassBuilt: effectiveness of an apprenticeship site-based smoking cessation intervention for unionized building trades workers
Blue-collar workers are difficult to reach and less likely to successfully quit smoking. The objective of this study was to test a training site-based smoking cessation intervention.
This study is a randomized-controlled trial of a smoking cessation intervention that integrated occupational health concerns and was delivered in collaboration with unions to apprentices at 10 sites (n = 1,213). We evaluated smoking cessation at 1 and 6 months post-intervention.
The baseline prevalence of smoking was 41%. We observed significantly higher quit rates in the intervention versus control group (26% vs. 16.8%; p = 0.014) 1 month after the intervention. However, the effects diminished over time so that the difference in quit rate was not significant at 6 month post-intervention (9% vs. 7.2%; p = 0.48). Intervention group members nevertheless reported a significant decrease in smoking intensity (OR = 3.13; 95% CI: 1.55â6.31) at 6 months post-intervention, compared to controls.
The study demonstrates the feasibility of delivering an intervention through union apprentice programs. Furthermore, the notably better 1-month quit rate results among intervention members and the greater decrease in smoking intensity among intervention members who continued to smoke underscore the need to develop strategies to help reduce relapse among blue-collar workers who quit smoking
Experimental constraints on a dark matter origin for the DAMA annual modulation effect
A claim for evidence of dark matter interactions in the DAMA experiment has
been recently reinforced. We employ a new type of germanium detector to
conclusively rule out a standard isothermal galactic halo of Weakly Interacting
Massive Particles (WIMPs) as the explanation for the annual modulation effect
leading to the claim. Bounds are similarly imposed on a suggestion that dark
pseudoscalars mightlead to the effect. We describe the sensitivity to light
dark matter particles achievable with our device, in particular to
Next-to-Minimal Supersymmetric Model candidates.Comment: v4: introduces recent results from arXiv:0807.3279 and
arXiv:0807.2926. Sensitivity to pseudoscalars is revised in light of the
first. Discussion on the subject adde
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Methods and Baseline Characteristics of Two Group-Randomized Trials With Multiracial and Multiethnic Working-class Samples
Introduction: Few papers address the methodological challenges in recruiting participants for studies of cancer prevention interventions designed for multiracial and multiethnic working-class populations. This paper reports the results of the sample selection and survey methods for two group-randomized intervention studies. Methods: The two group-randomized intervention studies, Healthy DirectionsâSmall Business (HDâSB) and Healthy DirectionsâHealth Centers (HDâHC), included a worksite-based study in 26 small manufacturing businesses and a study in 10 outpatient health centers. We used selection and recruitment methods to obtain a multiracial and multiethnic working-class study sample. In 2000 and 2001, we assessed baseline measures of sociodemographic characteristics and behavioral outcomes by self-report. We then computed intraclass correlation coefficients (ICCs). Results: Of the 1740 participants in the HDâSB study, 68% were non-Hispanic whites, and 76% had working-class occupations. In the HDâHC study, 59% of 2219 participants were non-Hispanic whites. Among those who worked, 51% had working-class occupations. Large percentages of both samples reported not meeting recommended guidelines for the target behaviors. For example, 86% of members of both samples consumed fewer than the recommended five servings of fruits and vegetables per day. The ICCs for the four target behaviors in HDâSB were between 0.006 and 0.02. In the HDâHC study, the ICCs ranged from 0.0004 to 0.003. Conclusion: The two studies were successful in recruiting multiracial and multiethnic working-class participants. Researchers will find the estimates of the primary outcomes and their ICCs useful for planning future studies
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