Author`s reply

To the Editor, We would like to thank the authors for their interest in our paper and their comments regarding our study entitled “A review of the fixed dose use of new oral anticoagulants in obese patients: Is it really enough?” published in Anatol J Cardiol 2015; 15: 1020-9 (1). Under-representation of obese patients in the subgroups of relevant studies raises concerns about the efficacy and safety of new oral anticoagulants (NOACs). The number of patients with high body weights is quite low in studies investigating the pharmacodynamics and pharmacokinetics of NOACs. In the context of data obtained from these studies, a fixed dose use of NOACs is recommended for obese or morbidly obese patients with no distinction from other patients

Which one is worse? Acute myocarditis and co-existing non-compaction cardiomyopathy in the same patient

WOS: 000422589400051PubMed ID: 26266155Non-compaction cardiomyopathy is a relatively rare cardiac condition known to be found in 0.12 per 100,000 cases characterized by increased trabeculations in the ventricular wall due to embryologic malformation predisposing malignant ventricular arrhythmias [1,2]. Although acute postviral myocarditis has been well-documented in the medical literature, co-existence of these two clinical entities is extremely uncommon [3-5]

Protez kapak endokardit komplikasyonunun değerlendirilmesinde multimodal görüntülemenin artan değeri

A 47-year-old male patient was admitted to the hospital with complaints of fever (38.3°C), palpitations, chills, and weakness. He had undergone a surgical graft interposition repair of the ascending aorta and aortic valve replacement (AVR) (No. 19; St. Jude Medical Inc., St. Paul, MN, USA) of the bicuspid aortic valve with severe aortic stenosis and an ascending aortic aneurysm 2 years earlier. Laboratory tests indicated a high erythrocyte sedimentation rate and an elevated white blood count and C-reactive protein level

Pacemaker lead ilişkili ciddi triküspit stenozu ve ciddi COVID-19 pnömoni hikayesi: Olgu sunumu

Tricuspid stenosis occurs after the implantation of a ventricular pacemaker lead and is a rare complication. An inflammatory response is stimulated when the pacemaker leads are passing through the tricuspid valve which leads to fibrosis in the long-term. In our case report, we aim to present a patient with asymptomatic multiple pacemaker lead- related tricuspid stenosis and with a history of severe COVID-19 pneumonia.Triküspit stenozu ventriküler pacemaker lead implantasyonu sonrası gelişen ve nadir görülen bir komplikasyondur. Pacemaker lead triküspit kapağı geçtiğinde inflamatuvar yanıt gelişir ve bu durum uzun dönemde fibroz ile sonuçlanır. Bu olgu sunumunun amacı, ağır geçirilmiş COVID-19 pnömonisi ve pacemaker lead ilişkili asemptomatik ciddi triküspit stenozu olan bir olguyu sunmaktır

An alternative malpractice system suggestion for Turkey: Patient compensation system

2015 Data Compression Conference, DCC 2015 -- 7 April 2015 through 9 April 2015 -- 113401Cocaine use has been related to the occurrence of myocardial infarction in young patients without other coronary risk factors. Acute myocardial infarction (AMI) secondary to the occlusion of the left main coronary artery (LMCA) in a cocaine user is infrequent, with sudden death being the most common form of presentation

Practical considerations on non-vitamin K oral anticoagulants in patients with high body weight

We have read with great interest the manuscript by Housseinsabet (1) entitled “Assessment of atrial conduction times in patients with mild diastolic dysfunction and normal atrial size,” published in the Anatolian Journal of Cardiology 2015; 15: 925-31. In this study, Hosseinsabet (1) clearly demonstrated that there were no differences in atrial conduction times (ACTs) and atrial electromechanical delays (EMDs) in patients with mild diastolic dysfunction and normal left atrial volume compared with normal subjects

Near zero fluoroscopy radiation exposure during successful catheter ablation of atrial tachycardia from the non-coronary aortic cusp using 3-dimentional electroanatomic mapping system

Atrial tachycardia (AT) rarely originates from the paraHisian region (1). Catheter ablation of paraHisian AT carries a substantial risk of atrioventricular (AV) block. Cryoablation offers a safer ablation strategy for these patients (2). There is a small risk of AV block with cryoablation. Ablation of paraHisian AT from the non-coronary aortic cusp (NCC) is an option in these patients. We report a patient with paraHisian AT that was successfully ablated from the NCC by 3-Dimentional (3-D) mapping system with using near zero fluoroscopy (NZF)

Right arcus aorta and Kommerell diverticulum: A rare challenge encountered as a consequence of increaesed left radial artery interventions

Kommerell divertikülü, dördüncü dorsal aortik arkın gelişim basamağındaki bir bozukluk nedeniyle saptanan ve nadir görülen bir anomalidir. Altmış dört yaşında kadın hasta, göğüs ağrısı şikayeti ile yapılan stres elektrokardiyografisinde iskemik değişiklik saptanması nedeniyle koroner anjiyografi amacıyla merkezimize yönlendirilmiş

Enhanced platelet reactivity in pediatric depression: An observational study

Congress of the European-Society-of-Cardiology (ESC) -- AUG 31-SEP 04, 2013 -- Amsterdam, NETHERLANDSWOS: 000327744605337Depression is associated with poor prognosis for Cardiovascular Disease (CVD) including mortality. Among multiple mechanisms linking depression and CVD, changes in platelet reactivity are known to be one of the major confounders of such adverse association. However, there are very limited data in children. Thus, we evaluated some conventional hemostatic indices including whole blood platelet aggregation in patients with documented pediatric depression and compared these data with those obtained from healthy children. The pediatric patients fulfilled criteria for major depression with a minimum score of 19 on the 21-item Beck Depression Inventory Scale. Plasma fibrinogen, D-dimer, platelet count, mean platelet volume, and platelet aggregation induced by Adenosine Diphosphate (ADP) and collagen were measured in 67 pediatric patients with depression and matched by age and sex with 78 healthy controlsEuropean Soc Cardio

An unknown side effect of isotretinoin: Pericardial effusion with atrial tachycardia

acne vulgaris and other dermatologic disorders. Systemic isotretinoin therapy may cause some cardiac side effects, like atrial tachycardia (1), congenital heart disease, and cardiac remodeling (2), reported as case reports. A 26-year-old female presented to the emergency unit of with syncope after a long palpitation episode. Her physical examination was normal except for tachycardia. A 12-lead electrocardiogram revealed atrial tachycardia, and the heart rate was 149 beats/min. After a 25-mg intravenous injection of diltiazem hydrochloride bolus, the atrial tachycardia terminated and normal sinus rhythm was sustained. Her laboratory tests and chest X-ray were normal. Echocardiography revealed normal left ventricular function and pericardial effusion of 0.8 cm at posterior side, 0.9 cm at the right atrial side and 1.3 cm at the right ventricle side. Several atrial tachycardia episodes were detected on rhythm Holter. During the longest episode of atrial tachycardia, the heart rate was 149 beats/min. The patient had been on oral isotretinoin therapy of 0.5 mg/kg/day for the previous 4 months because of nodular acne and was not using any other medication. After consulting with a dermatology physician, isotretinoin was stopped. Holter analysis revealed whole-day sinus rhythm 2 months after the drug therapy was interrupted. Echocardiography revealed gradual regression of pericardial effusion at the follow-up