20 research outputs found
Role of Umklapp Processes in Conductivity of Doped Two-Leg Ladders
Recent conductivity measurements performed on the hole-doped two-leg ladder
material reveal an approximately linear
power law regime in the c-axis DC resistivity as a function of temperature for
. In this work, we employ a bosonic model to argue that umklapp processes
are responsible for this feature and for the high spectral weight in the
optical conductivity which occurs beyond the finite frequency Drude-like peak.
Including quenched disorder in our model allows us to reproduce experimental
conductivity and resistivity curves over a wide range of energies. We also
point out the differences between the effect of umklapp processes in a single
chain and in the two-leg ladder.Comment: 10 pages, 2 figure
Thermal Conductivity of Spin-1/2 Chains
We study the low-temperature transport properties of clean one-dimensional
spin-1/2 chains coupled to phonons. Due to the presence of approximate
conservation laws, the heat current decays very slowly giving rise to an
exponentially large heat conductivity, . As a result of an
interplay of Umklapp scattering and spinon-phonon coupling, the characteristic
energy scale turns out to be of order , where is
the Debye energy, rather than the magnetic exchange interaction -- in
agreement with recent measurements in SrCuO compounds. A large magnetic field
strongly affects the heat transport by two distinct mechanisms. First, it
induces a LINEAR spinon--phonon coupling, which alters the nature of the fixed point: the elementary excitations of the system are COMPOSITE
SPINON-PHONON objects. Second, the change of the magnetization and the
corresponding change of the wave vector of the spinons strongly affects the way
in which various Umklapp processes can relax the heat current, leading to a
characteristic fractal--like spiky behavior of when plotted as a
function of magnetization at fixed T.Comment: 16 pages, RevTex4, 2 figures included; revised refs. and some useful
comments on experimental relevance. On July 12 2005, added an appendix
correcting an error in the form of the phonon propagator. The main result is
unchange
Transitions between Inherent Structures in Water
The energy landscape approach has been useful to help understand the dynamic
properties of supercooled liquids and the connection between these properties
and thermodynamics. The analysis in numerical models of the inherent structure
(IS) trajectories -- the set of local minima visited by the liquid -- offers
the possibility of filtering out the vibrational component of the motion of the
system on the potential energy surface and thereby resolving the slow
structural component more efficiently. Here we report an analysis of an IS
trajectory for a widely-studied water model, focusing on the changes in
hydrogen bond connectivity that give rise to many IS separated by relatively
small energy barriers. We find that while the system \emph{travels} through
these IS, the structure of the bond network continuously modifies, exchanging
linear bonds for bifurcated bonds and usually reversing the exchange to return
to nearly the same initial configuration. For the 216 molecule system we
investigate, the time scale of these transitions is as small as the simulation
time scale ( fs). Hence for water, the transitions between each of
these IS is relatively small and eventual relaxation of the system occurs only
by many of these transitions. We find that during IS changes, the molecules
with the greatest displacements move in small ``clusters'' of 1-10 molecules
with displacements of nm, not unlike simpler liquids.
However, for water these clusters appear to be somewhat more branched than the
linear ``string-like'' clusters formed in a supercooled Lennar d-Jones system
found by Glotzer and her collaborators.Comment: accepted in PR
In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma
CXCR4 is a G-protein-coupled receptor that mediates recruitment of blood cells toward its ligand SDF-1. In cancer, high CXCR4 expression is frequently associated with tumor dissemination and poor prognosis. We evaluated the novel CXCR4 probe [(68)Ga]Pentixafor for in vivo mapping of CXCR4 expression density in mice xenografted with human CXCR4-positive MM cell lines and patients with advanced MM by means of positron emission tomography (PET). [(68)Ga]Pentixafor PET provided images with excellent specificity and contrast. In 10 of 14 patients with advanced MM [(68)Ga]Pentixafor PET/CT scans revealed MM manifestations, whereas only nine of 14 standard [(18)F]fluorodeoxyglucose PET/CT scans were rated visually positive. Assessment of blood counts and standard CD34(+) flow cytometry did not reveal significant blood count changes associated with tracer application. Based on these highly encouraging data on clinical PET imaging of CXCR4 expression in a cohort of MM patients, we conclude that [(68)Ga]Pentixafor PET opens a broad field for clinical investigations on CXCR4 expression and for CXCR4-directed therapeutic approaches in MM and other diseases
Géodynamique andine : résumés étendus = Andean geodynamics : extended abstracts
Nous prĂ©sentons ici les rĂ©sultats d'investigations gravimĂ©triques et sismiques dans les Andes Centrales du sud (20°-28° S) effectuĂ©es durant les annĂ©es 80 et le dĂ©but des annĂ©es 90. Les structures grossiĂšres de la croĂ»te peuvent ĂȘtre dĂ©terminĂ©es de maniĂšre Ă couvrir les unitĂ©s morphostructurales principales des Andes entre 21° et 25° sud. Les investigations gravimĂ©triques et sismiques ont Ă©tĂ© centrĂ©es sur les structures de l'arc et de l'avant-arc afin de fournir une connaissance plus dĂ©taillĂ©e de la structure de la croĂ»te dans cette rĂ©gion. (RĂ©sumĂ© d'auteur
Géodynamique andine : résumés étendus = Andean geodynamics : extended abstracts
De 1993 à 1995, le groupe international MIGRA constitué de participants du Chili, d'Argentine et d'Allemagne ont relevé environ 2000 nouvelles mesures gravimétriques le long d'un géotraverse des Andes couvrant le nord du Chili et le nord-ouest de l'Argentine entre 64°-71° ouest et 20°-29° sud. La base de données comprenant les coordonnées des stations, des grilles de données de 10x10 km de l'anomalie à l'air libre, de différents types d'anomalies de Bouguer ainsi que l'anomalie isostatique résiduelle sont ici représentés dans une carte du champ isostatique résiduel, avec une interprétation sommaire. (Résumé d'auteur
Knochenmarktransplantation bei akuter Leukämie: Prophylaktische Antiserumbehandlung des Knochenmarks zur Unterdrückung einer Transplantat-gegen-Wirt-Reaktion.
Anti-human-thymocyte globulin (AHTZG) was applied to prevent GvHD in clinical bone marrow transplantation. AHTZG produced by absorption with several cell preparations reacted specifically with T-lymphocyte populations and was no longer inhibitory to human CFUc and bone marrow growth in diffusion chambers. Marrow grafts of 14 patients with ALL were incubated in vitro with AHTZG and transferred to the recipients conditioned with antileukemic chemotherapy and total body irradiation of 1000 rad. Ten patients were transplanted after relaps, four patients during remission. The patients tolerated the marrow without side effects and a hemopoietic engraftment was seen in 12 cases. Three patients showed signs of GvHD on the skin, two of them showed later on also manifestations in the liver. In the other cases no GvHD could be detected. Five out of 14 patients are still alive between 144 and 964 days post transplantation in remission