Interaction between the SNP rs4132601 (<i>IKZF1</i>) and maternal use of home insecticides during pregnancy, preconception paternal smoking, breastfeeding, repeated early common infections and birth order, in their relation with childhood acute lymphoblastic leukemia.

<p>CI: confidence interval; OR: odds ratio; SNP: Single nucleotide polymorphism.</p><p>*:p<0.05;</p><p>**: p<0.01;</p><p>***: p<0.001</p><p>^a OR and 95% CI estimated by unconditional logistic models including gender and age and parental socio-professional category.</p><p>^b Restriction to children ≥ 1 year old</p><p>Interaction between the SNP rs4132601 (<i>IKZF1</i>) and maternal use of home insecticides during pregnancy, preconception paternal smoking, breastfeeding, repeated early common infections and birth order, in their relation with childhood acute lymphoblastic leukemia.</p

Interaction between the SNP rs10740055 (<i>ARID5B</i>) and maternal use of home insecticides during pregnancy, preconception paternal smoking, breastfeeding, repeated early common infections and birth order, in their relation with childhood acute lymphoblastic leukemia.

<p>CI: confidence interval; OR: odds ratio; SNP: Single nucleotide polymorphism.</p><p>^a OR and 95% CI estimated by unconditional logistic models including gender and age and parental socio-professional category.</p><p>^b Restriction to children ≥ 1 year old</p><p>*: p<0.05;</p><p>**: p<0.01;</p><p>***: p<0.001</p><p>Interaction between the SNP rs10740055 (<i>ARID5B</i>) and maternal use of home insecticides during pregnancy, preconception paternal smoking, breastfeeding, repeated early common infections and birth order, in their relation with childhood acute lymphoblastic leukemia.</p

Joint associations between childhood acute lymphoblastic leukemia (ALL) and the variables combining the non-genetic factors of interest with rs10740055 <i>(ARID5B)</i> and rs4132601 <i>(IKZF1)</i> polymorphisms. The analyses addressing common infections were restricted to the children aged one year or more (398 controls and 426 ALL), while the analyses addressing the other exposures were based on the whole sample (442 controls and 434 ALL).

<p>ALL: acute lymphoblastic leukemia; CI: confidence interval; Co: controls; OR: odds ratio; SNP: Single nucleotide polymorphism.</p><p>*: <i>P</i><0.05;</p><p>**: <i>P</i><0.01;</p><p>***: <i>P</i><0.001</p><p>^a OR and 95% CI estimated by unconditional logistic models including gender and age and parental socio-professional category.</p><p>^b Restriction to children ≥ 1 year old</p><p>Joint associations between childhood acute lymphoblastic leukemia (ALL) and the variables combining the non-genetic factors of interest with rs10740055 <i>(ARID5B)</i> and rs4132601 <i>(IKZF1)</i> polymorphisms. The analyses addressing common infections were restricted to the children aged one year or more (398 controls and 426 ALL), while the analyses addressing the other exposures were based on the whole sample (442 controls and 434 ALL).</p

Associations between childhood acute lymphoblastic leukemia (ALL) and rs4132601 (<i>IKZF1</i>) polymorphisms by non-genetic factors: allelic OR in the whole sample and by ALL major subtypes, in the ESCALE study, France 2003–2004.

<p>ALL: acute lymphoblastic leukemia; B-com ALL: common B-cell ALL; CI: confidence interval; OR: odds ratio; p int: p for interaction</p><p>*:p<0.05;</p><p>**: p<0.01;</p><p>***: p<0.001</p><p>^a Allelic OR and 95% CI estimated by unconditional logistic models adjusted for gender, age and parental socio-professional category.</p><p>^b children ≥ 1 year old</p><p>Associations between childhood acute lymphoblastic leukemia (ALL) and rs4132601 (<i>IKZF1</i>) polymorphisms by non-genetic factors: allelic OR in the whole sample and by ALL major subtypes, in the ESCALE study, France 2003–2004.</p