Stress Intensity Factor using Finite Element Analysis in Rectangular Orthotropic Composite Annular Disk

The quadratic isoparametric elements which embody the inverse squareroot singularity were used to determine the stress intensity factor in an annular disk made of Boron-Epoxy composite material. The displacements and stresses were determined in a rectangular orthotropic composite annular disk using isoparametric finite elements. The singularity in the strain field was provided by means of 8-noded isoparametric elements (4-nodes at the four corners and four mid-side nodes each at l/4th distance from the edge). The results were obtained for various material properties and fibre orientation. The geometry of the annular disk was reported when subjected to a boundary radial and tangential. The r singularity was provided at the boundary of the circular hole and the rest of the annular disk was modelled with ordinary isoparametric elements. The apparent stress intensity factor (K/sub I/=) was computed from the stress data near the circular hole, when it was subjected to uniform tension. A curve was drawn for apparent stress intensity factor versus the distance from the crack edge and was extrapolated to r = 0, the actual stress intensity factor was found on the y-axis

Nonadiabatic effects in the H+H_2 exchange reaction: accurate quantum dynamics calculations at a state-to-state level

Real wave packet propagations were carried out on both a single ground electronic state and two-coupled-electronic states of the title reaction to investigate the extent of nonadiabatic effects on the distinguishable-atom reaction cross sections. The latest diabatic potential matrix of Abrol and Kuppermann [J. Chem. Phys. 116, 1035 (2002)] was employed in the present nonadiabatic quantum state-to-state scattering calculations over a total energy range-from threshold (the zero point of the reagent H_2) to 3.0 eV. Based on the assumption that the hydrogen atoms are distinguishable in the collisions where the inelastic and elastic ones are excluded, no significant nonadiabatic effects have been found in the calculations of the full state-to-state integral and differential cross sections up to a total energy of 3.0 eV for product vibrational levels v' = 0, 1, 2, 3. Our results therefore confirm the recent and the previous studies of the geometric phase effects in H+H_2 employing a different diabatic double many-body expansion potential matrix or a different BKMP2 potential energy surface

Cellular Correlates of Enhanced Anxiety Caused by Acute Treatment with the Selective Serotonin Reuptake Inhibitor Fluoxetine in Rats

Selective serotonin reuptake inhibitors (SSRIs) are used extensively in the treatment of depression and anxiety disorders. The therapeutic benefits of SSRIs typically require several weeks of continuous treatment. Intriguingly, according to clinical reports, symptoms of anxiety may actually increase during the early stages of treatment although more prolonged treatment alleviates affective symptoms. Consistent with earlier studies that have used animal models to capture this paradoxical effect of SSRIs, we find that rats exhibit enhanced anxiety-like behavior on the elevated plus-maze 1 h after a single injection of the SSRI fluoxetine. Next we investigated the potential neural substrates underlying the acute anxiogenic effects by analyzing the morphological and physiological impact of acute fluoxetine treatment on principal neurons of the basolateral amygdala (BLA), a brain area that plays a pivotal role in fear and anxiety. Although earlier studies have shown that behavioral or genetic perturbations that are anxiogenic for rodents also increase dendritic spine density in the BLA, we find that a single injection of fluoxetine does not cause spinogenesis on proximal apical dendritic segments on BLA principal neurons an hour later. However, at the same time point when a single dose of fluoxetine caused enhanced anxiety, it also enhanced action potential firing in BLA neurons in ex vivo slices. Consistent with this finding, in vitro bath application of fluoxetine caused higher spiking frequency and this increase in excitability was correlated with an increase in the input resistance of these neurons. Our results suggest that enhanced excitability of amygdala neurons may contribute to the increase in anxiety-like behavior observed following acute fluoxetine treatment

Seasonal variation of heavy metals in Subarnarekha River at Jamshedpur, East Singhbhum, Jharkhand

The present investigation is aimed at assessing the amount of heavy metals andcurrent water quality standard along the Subarnarekha river in Jharkhand. Three samples were collected along the stretches of Subarnarekha basin during the period : Jan-Dec, 2015, on the first week of every month. The concentrations Cu, Pb, Ni, Zn, Cr, Co, Sr, Cd and Fe were determined using inductively coupled plasma mass spectrometry for seasonal fluctuation, source apportionment and heavy metal pollution indexing. The results demonstrated that concentrations of the metals showed significant seasonality. To assess the composite influence of all the considered metals on the overall quality of the water, heavy metal pollution indices were calculated. The deterioration of water quality and enhanced concentrations of certain metals in the Subarnarekha River near industrial and mining establishments may be attributed to anthropogenic contribution from the industrial and mining activities of the area. Various physicochemical parameters like pH, TDS, EC, DO, BOD, Total Hardness, Total alkalinity sodium, potassium, calcium, magnesium etc. were also analysed. Eight parameters namely pH, Dissolved Oxygen, Biochemical Oxygen Demand, Nitrate, Phosphate, Total Dissolved Solids and Faecal Colliform were considered to compute Water Quality Index (WQI) based on National Sanitation Foundation studies and discussed

Lyapunov-based backward-horizon adaptive stabilization

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/57828/1/RaviACSP2003.pd

A Community Based Study on the Role of Maternal Education on Antenatal Care Services and Child Care at Various Tribal Villages, Adilabad, Telangana State

Background: Educated women tend to have a greater awareness of the existence of ANC services, more aware of health problems, know more about the availability of health care services, and utilize the information more effectively than non-educated women. Moreover, higher levels of education tend to positively affect healthseeking behaviors, and education may increase a woman’s control over her pregnancy and expose women to more health education messages and campaigns, enabling them to recognize danger signs and complications and take appropriate action. In this study, we tried to analyze to what level the maternal education can influence the antenatal care services and childcare. Methods: A community-based cross-sectional study was conducted on 93 randomly selected mothers who have children less than 7 years by using a pre-tested structured questionnaire for data collection at various tribal villages, at an average 25 kms away from Adilabad town from April-October 2019. Analysis was done using SPSS for windows version 16, Microsoft excel and Open epi website. Results: Out of 93 study subjects, 19.3% (18) of the study subjects were not registered for the antenatal services. Higher the maternal education higher the age at pregnancy (p\u3c0.05), was associated with more preference for deliveries by doctors (p\u3c0.05). More the frequency of exclusive breast feeding, long lasting breast feeding was associated more than a year (p\u3c0.05), a smaller number of children with wasting (p\u3c0.05). Conclusion: This study revealed that utilization of ANC services was relatively better for the mother’s educated higher than secondary school, but they are still low. Educational status is important in having more health seeking behavior. In this study, it proves that health education is more important than the mere school education which can help to improve knowledge on ANC

RECOGNIZATION OF AUTHORISED PEOPLES IN COLLAGE BY USING RFID TECHNOLOGY WITH IOT PLATFORM

In this task explains an automated presence administration system that could be used at expert events of various kinds (meetings, events, training programs, and so on) as well as ranges (from small-to-medium workshops and also workshops to big congresses as well as technological programs). The system is based upon application of RFID, mobile interaction as well as IT modern technologies. It can accumulating, taping as well as refining information on individuals of a technological celebration and also their tasks, participation or various sessions, seeing various exhibit cubicles, and so on. The system could additionally create real-time mixed information records on presence, inflow and also discharge of the individuals throughout the occasion, their most as well as the very least favored rate of interests as well as tasks, and so on. This could be provided for a wide range of places as well as facilities, and also throughout an extensive amount of time

Associations between purine metabolites and clinical symptoms in schizophrenia

Background: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology of schizophrenia. Methodology/Principal Findings: Breakdown products in purine pathway were measured using high-pressure liquid chromatography coupled with a coulometric multi-electrode array system for 25 first-episode neuroleptic-naïve patients with schizophrenia at baseline and at 4-weeks following initiation of treatment with antipsychotic medication. Associations between these metabolites and clinical and neurological symptoms were examined at both time points. The ratio of uric acid and guanine measured at baseline predicted clinical improvement following four weeks of treatment with antipsychotic medication. Baseline levels of purine metabolites also predicted clinical and neurological symtpoms recorded at baseline; level of guanosine was associated with degree of clinical thought disturbance, and the ratio of xanthosine to guanosine at baseline predicted degree of impairment in the repetition and sequencing of actions. Conclusions/Significance: Findings suggest an association between optimal levels of purine byproducts and dynamics in clinical symptoms and adjustment, as well as in the integrity of sensory and motor processing. Taken together, alterations in purine catabolism may have clinical relevance in schizophrenia pathology

Synthesis, Spectral Characterization and Antimicrobial Studies of Co(II) Complexes with Tetradentate Schiff bases Derived from Ortho-Phthalaldehyde

A series of cobalt (II) complexes have been synthesized with Schiff bases derived from ortho-phthalaldehyde and various amines in aqueous methanol solution. The newly synthesized Schiff bases and their Co (II) complexes have been characterized  by elemental analysis, magnetic susceptibility, thermal, conductance measurements, mass, IR, electronic, 1H,13C-NMR spectral techniques. These ligands act as tetradentate species and coordinate to the metal center through the different potential donor atoms such as N, O and S. The probable octahedral structures have been assigned to these complexes. All the synthesized Schiff base ligands and Co(II) metal complexes have also been screened for their antimicrobial activities and metal complexes found to be more active than respective Schiff-base ligands