Wykorzystanie gazu w źródłach rozproszonych w dużych systemach ciepłowniczych

The aim of an investigation was to examine the heat sources, which can be used as a supplement for providing the heat for the users at the ends of extensive heating networks. The research was based on the technical and economic analysis that also included ecological effects. The integral element of the research was a comparative analysis of such distributed heat sources and the current heating systems regarding their mutual competitiveness factors or supplementation.W pracy zaprezentowano rozważania dotyczące ekonomicznej celowości instalacji zastosowania źródeł rozproszonych w ciepłownictwie. Pomysl zastosowania źródeł rozproszonych w ciepłownictwie podobny jest do tego obecnie szeroko dyskutowanego pomysłu źródeł rozproszonych do produkcji energii elektrycznej. Ze względu na obecne warunki ekonomiczne do rozważań wybrano źródła zasilane gazem ziemnym. Zaproponowano pięć sposób zasilania odbiorców na końcach rozległych sieci ciepłowniczych. Dla przedstawionych wariantów wykonano analizy ekonomiczne, których wyniki przedstawiona w pracy

Effectiveness of botulinum toxin injection in the treatment of de novo OAB symptoms following midurethral sling surgery

Introduction and hypothesis Intravesical onabotulinumtoxinA (Botox®) is effective for idiopathic overactive bladder (OAB) symptoms. Our primary objective was to compare the efficacy of onabotulinumtoxinA for women with de novo OAB after midurethral sling (MUS) surgery and women with idiopathic OAB. Methods Women enrolled in this prospective study had idiopathic (n=53) or de novo (n=49) OAB symptoms after MUS, with at least one episode of urgency urine incontinence per day. OnabotulinumtoxinA (100 U) was administered in 20 intradetrusor injections. Postvoid residual volumes were checked at 2, 4 and 12 weeks. Participants completed a 3- day bladder diary and the King’s Health Questionnaire (KHQ) before and 12 weeks after treatment. Results After 12 weeks, 22 patients (41.5 %) in the idiopathic OAB and 19 patients (38.8 %) in the de novo OAB groups were completely dry. OnabotulinumtoxinA injections had a significant benefit within both groups (p 90 ml in both groups. Urinary retention was observed in four patients. Conclusions We observed similar improvement in OAB symptoms after intravesical onabotulinumtoxinA injections within both groups. The rates of retention and requirement for catheterization even for women with a prior MUS were acceptable. These observational data provide evidence that onabotulinumtoxinA can effectively treat patients with OAB following stress urinary incontinence surger