NITRIFICATION TREATMENT OF AMMONIUM POLLUTED HANOI GROUNDWATER USING A SWIM-BED TECHNOLOGY

Joint Research on Environmental Science and Technology for the Eart

A Rare Complication of Retrograde Ejaculation after Lumbar Sympathetic Block and its Spontaneous Recovery : A Case Report

Article信州医学雑誌 69(1): 53-56(2021)journal articl

PARTIAL NITRITATION OF SYNTHETIC LANDFILL LEACHATE IN AN ATTACHED IMMOBILIZED REACTOR WITH ACRYL FIBER BIOMASS CARRIER

Joint Research on Environmental Science and Technology for the Eart

BIOLOGICAL NITRIFICATION-DENITRIFICATION TREATMENT OF AMMONIUM NITROGEN POLLUTED HANOI- GROUNDWATER USING A NOVEL ACRYL-RESIN FIBER FOR BIOMASS ATTACHMENT

Joint Research on Environmental Science and Technology for the Eart

Structural dynamics of double-stranded DNA with epigenome modification

メチル基1つでDNAの運動性が変わることを解明 --運動性というDNA上の目印--. 京都大学プレスリリース. 2020-12-23.Modification of cytosine plays an important role in epigenetic regulation of gene expression and genome stability. Cytosine is converted to 5-methylcytosine (5mC) by DNA methyltransferase; in turn, 5mC may be oxidized to 5-hydroxymethylcytosine (5hmC) by ten-eleven translocation enzyme. The structural flexibility of DNA is known to affect the binding of proteins to methylated DNA. Here, we have carried out a semi-quantitative analysis of the dynamics of double-stranded DNA (dsDNA) containing various epigenetic modifications by combining data from imino 1H exchange and imino 1H R1ρ relaxation dispersion NMR experiments in a complementary way. Using this approach, we characterized the base-opening (kopen) and base-closing (kclose) rates, facilitating a comparison of the base-opening and -closing process of dsDNA containing cytosine in different states of epigenetic modification. A particularly striking result is the increase in the kopen rate of hemi-methylated dsDNA 5mC/C relative to unmodified or fully methylated dsDNA, indicating that the Watson–Crick base pairs undergo selective destabilization in 5mC/C. Collectively, our findings imply that the epigenetic modulation of cytosine dynamics in dsDNA mediates destabilization of the GC Watson–Crick base pair to allow base-flipping in living cells

DENITIRIFICATION TREATMENT OF NITRIFIED HANOI GROUNDWATER USING SWIM BED TECHNOLOGY

Joint Research on Environmental Science and Technology for the Eart

STUDIES ON NITROGEN REMOVAL PERFORMANCES FOR SINGLE STAGE NITROGEN REMOVAL USING ANAMMOX AND PARTIAL NITRITATION (SNAP) PROCESS

Joint Research on Environmental Science and Technology for the Eart

Nitrification of Groundwater Contaminated with NH₄⁺ Using a Novel Acryl-Resin Fiber for Biomass Attachment

Joint Research on Environmental Science and Technology for the Eart