Factorization of the Abel-Jacobi maps

As an application of the theory of Lawson homology and morphic cohomology, Walker proved that the Abel-Jacobi map factors through another regular homomorphism. In this note, we give a direct proof of the theorem.Comment: 9 pages, comments are welcome, published versio

Two coniveau filtrations and algebraic equivalence over finite fields

We extend the basic theory of the coniveau and strong coniveau filtrations to the $\ell$-adic setting. By adapting the examples of Benoist--Ottem to the $\ell$-adic context, we show that the two filtrations differ over any algebraically closed field of characteristic not $2$. When the base field $\mathbb{F}$ is finite, we show that the equality of the two filtrations over the algebraic closure $\overline{\mathbb{F}}$ has some consequences for algebraic equivalence for codimension-$2$ cycles over $\mathbb{F}$. As an application, we prove that the third unramified cohomology group $H^{3}_{\text{nr}}(X,\mathbb{Q}_{\ell}/\mathbb{Z}_{\ell})$ vanishes for a large class of rationally chain connected threefolds $X$ over $\mathbb{F}$, confirming a conjecture of Colliot-Th\'el\`ene and Kahn.Comment: 30 pages, comments are welcome. This is an expanded version of the second part of arXiv:2206.12732v

Re-calibration of SDF/SXDS Photometric Catalogs of Suprime-Cam with SDSS Data Release 8

We present photometric recalibration of the Subaru Deep Field (SDF) and Subaru/XMM-Newton Deep Survey (SXDS). Recently, Yamanoi et al. (2012) suggested the existence of a discrepancy between the SDF and SXDS catalogs. We have used the Sloan Digital Sky Survey (SDSS) Data Release 8 (DR8) catalog and compared stars in common between SDF/SXDS and SDSS. We confirmed that there exists a 0.12 mag offset in B-band between the SDF and SXDS catalogs. Moreover, we found that significant zero point offsets in i-band (~ 0.10 mag) and z-band (~ 0.14 mag) need to be introduced to the SDF/SXDS catalogs to make it consistent with the SDSS catalog. We report the measured zero point offsets of five filter bands of SDF/SXDS catalogs. We studied the potential cause of these offsets, but the origins are yet to be understood.Comment: 36 pages, 19 figures(128 EPS files), PASJ accepte

The Representative Porcine Model for Human Cardiovascular Disease

To improve human health, scientific discoveries must be translated into practical applications. Inherent in the development of these technologies is the role of preclinical testing using animal models. Although significant insight into the molecular and cellular basis has come from small animal models, significant differences exist with regard to cardiovascular characteristics between these models and humans. Therefore, large animal models are essential to develop the discoveries from murine models into clinical therapies and interventions. This paper will provide an overview of the more frequently used large animal models, especially porcine models for preclinical studies

Purification of functional baculovirus particles from silkworm larval hemolymph and their use as nanoparticles for the detection of human prorenin receptor (PRR) binding

<p>Abstract</p> <p>Background</p> <p>Baculovirus, which has a width of 40 nm and a length of 250-300 nm, can display functional peptides, receptors and antigens on its surface by their fusion with a baculovirus envelop protein, GP64. In addition, some transmembrane proteins can be displayed without GP64 fusion, using the native transmembrane domains of the baculovirus. We used this functionality to display human prorenin receptor fused with GFP_uv(GFP_uv-hPRR) on the surface of silkworm <it>Bombyx mori </it>nucleopolyhedrovirus (BmNPV) and then tested whether these baculovirus particles could be used to detect protein-protein interactions.</p> <p>Results</p> <p>BmNPV displaying GFP_uv-hPRR (BmNPV-GFP_uv-hPRR) was purified from hemolymph by using Sephacryl S-1000 column chromatography in the presence of 0.01% Triton X-100. Its recovery was 86% and the final baculovirus particles number was 4.98 × 10⁸pfu. Based on the results of enzyme-linked immunosorbent assay (ELISA), 3.1% of the total proteins in BmNPV-GFP_uv-hPRR were GFP_uv-hPRR. This value was similar to that calculated from the result of western blot by a densitometry (2.7%). To determine whether BmNPV-GFP_uv-hPRR particles were bound to human prorenin, ELISA results were compared with those from ELISAs using protease negative BmNPV displaying β1,3-<it>N</it>-acetylglucosaminyltransferase 2 fused with the gene encoding GFP_uv(GGT2) (BmNPV-<it>CP</it>^--GGT2) particles, which do not display hPRR on their surfaces.</p> <p>Conclusion</p> <p>The display of on the surface of the BmNPV particles will be useful for the detection of protein-protein interactions and the screening of inhibitors and drugs in their roles as nanobioparticles.</p