A Family of Subgradient-Based Methods for Convex Optimization Problems in a Unifying Framework

We propose a new family of subgradient- and gradient-based methods which converges with optimal complexity for convex optimization problems whose feasible region is simple enough. This includes cases where the objective function is non-smooth, smooth, have composite/saddle structure, or are given by an inexact oracle model. We unified the way of constructing the subproblems which are necessary to be solved at each iteration of these methods. This permitted us to analyze the convergence of these methods in a unified way compared to previous results which required different approaches for each method/algorithm. Our contribution rely on two well-known methods in non-smooth convex optimization: the mirror-descent method by Nemirovski-Yudin and the dual-averaging method by Nesterov. Therefore, our family of methods includes them and many other methods as particular cases. For instance, the proposed family of classical gradient methods and its accelerations generalize Devolder et al.'s, Nesterov's primal/dual gradient methods, and Tseng's accelerated proximal gradient methods. Also our family of methods can partially become special cases of other universal methods, too. As an additional contribution, the novel extended mirror-descent method removes the compactness assumption of the feasible region and the fixation of the total number of iterations which is required by the original mirror-descent method in order to attain the optimal complexity.Comment: 31 pages. v3: Major revision. Research Report B-477, Department of Mathematical and Computing Sciences, Tokyo Institute of Technology, February 201

Examination on unsteady aerodynamical characteristics of airfoil by a vortex method

Unsteady aerodynamical effect of accelerated or decelerated two-dimensional airfoil (NACA0012) was numerically examined using a grid-free vortex method. The flow characteristics and aerodynamical forces were compared among various accelerated or decelerated conditions. The results showed that flow separation occurred under decelerated condition and the lift-drag ratio decreased as the decelerated velocity became high and increased as the accelerated velocity became high

<ORIGINAL REPORT>IMMUNOHISTOCHEMICAL STUDIES ON LACTATE DEHYDROGENASE SUBUNITS IN LUNG CANCER CELLS

この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。Immunohistochemical distribution of lactate dehydrogenase (LDH) subunits in human lung cancer cells were studied using fluorescent antibody technique. Both in cytological and histological specimen, specific fluorescence of LDH-H and LDH-M were seen in the cytoplasm of cancer cells, and in most cases no remarkable difference could be demonstrated between the distribution of H and M subunit. But in some cases specific fluorescence of M-subunit was stronger than that of H-subunit. The fluorescence of M-subunit was demonstrated as fine granules diffusely in the cytoplasm. On the other hand the fluorescence of H-subunit was rather localized and demonstrated as rather coarse granules. And this observation was discussed

Continuous perfusion of pulmonary arteries during total cardiopulmonary bypass favorably affects levels of circulating adhesion molecules and lung function

AbstractObjectives: Lung injury is a serious complication of cardiopulmonary bypass in infants with congenital heart disease and pulmonary hypertension. Cessation of blood flow in the pulmonary arteries during cardiopulmonary bypass is known to provoke lung dysfunction. We assessed the effect of continuous pulmonary perfusion on circulating adhesion molecules and on lung function. Methods: Fourteen infants with congenital heart disease and pulmonary hypertension were enrolled in the study. During total cardiopulmonary bypass, 8 patients underwent continuous perfusion of the pulmonary arteries (perfusion group), and the remaining 6 patients did not (control group). Plasma levels of circulating intercellular adhesion molecule 1, soluble granule membrane protein 140, and sialyl Lewisx and PaO2/fraction of inspired oxygen ratios were measured before commencement and serially for 24 hours after termination of bypass. Results: Plasma levels of circulating intercellular adhesion molecule 1 decreased significantly at the termination of bypass in both groups but returned to prebypass levels immediately in the control group, whereas in the perfusion group the values remained significantly less than those before bypass. Plasma levels of soluble granule membrane protein 140 in the control group were significantly higher at 6 and 12 hours after bypass than levels before bypass, whereas in the perfusion group the values remained at the prebypass level throughout the postbypass period. Trends of plasma levels of sialyl Lewisx were alike in both groups. PaO2/fraction of inspired oxygen ratios in the control group decreased significantly from 6 hours after bypass, whereas values in the perfusion group remained at the prebypass value throughout the postbypass period. Conclusions: This study suggests that in infants having congenital heart disease and pulmonary hypertension, continuous pulmonary perfusion during total cardiopulmonary bypass minimizes ischemic insult and neutrophil-endothelial interaction mediated by adhesion molecules in the pulmonary microvessels.J Thorac Cardiovasc Surg 2001;122:242-

STANDARD MOTION OF SPRINT RUNNING FOR MALE ELITE AND STUDENT SPRINTERS

The purpose of this study was to show standard motion models of male elite and student sprinters and investigate the characteristics of the elite sprinters’ motion. Fourteen male international level sprinters and twenty-one male student sprinters were videotaped at the maximum running velocity phase, standard motion models were prepared and kinematic variables were then calculated. Running velocity, stride length, release distance and flight distance of the elite sprinters were significantly greater than in the student sprinters. The elite sprinters did not fully extend the knee and ankle joints of the support leg at the toeoff while the student sprinters tended to show the converse motion. Student sprinters should use hip joint extension rather than flexion-extension of the knee and ankle joints, and should keep the shank leaning forward during the support phase

Development of Large Volume Neutron Detector

開始ページ、終了ページ: 冊子体のページ付

Clinical Evaluation of Cancer Diagnosis with 18F-2-Deoxy-2-Fluoro(18F)-D-Glucose: Its Usefulness in Liver and Pancreatic Cancers

開始ページ、終了ページ: 冊子体のページ付

Japanese Encephalitis Virus in Meningitis Patients, Japan

Cerebrospinal fluid specimens from 57 patients diagnosed with meningitis were tested for Japanese encephalitis virus. Total RNA was extracted from the specimens and amplified. Two products had highest homology with Nakayama strain and 2 with Ishikawa strain. Results suggest that Japanese encephalitis virus causes some aseptic meningitis in Japan