Pregnancy in porphyria and its complications: a case report

As with many rare diseases, little is known about the porphyrias and reproduction. Knowledge pertaining to complications in pregnancy in a patient with porphyria is even more scant. The information which we have is from attending on individual cases. The following case report demonstrates a rare case of porphyria cutanea tarda in a 30 year old female patient, diagnosed around pubertal age, who presented to the Emergency department as a case of severe anemia who had delivered a still born baby the same day. Still births along with spontaneous abortions, preeclampsia and low birth weights are few of the known complications of pregnancy in patients with porphyria

New Samarium and Neodymium based admixed ferromagnets with near zero net magnetization and tunable exchange bias field

Rare earth based intermetallics, SmScGe and NdScGe, are shown to exhibit near zero net magnetization with substitutions of 6 to 9 atomic percent of Nd and 25 atomic percent of Gd, respectively. The notion of magnetic compensation in them is also elucidated by the crossover of zero magnetization axis at low magnetic fields (less than 103 Oe) and field-induced reversal in the orientation of the magnetic moments of the dissimilar rare earth ions at higher magnetic fields. These magnetically ordered materials with no net magnetization and appreciable conduction electron polarization display an attribute of an exchange bias field, which can be tuned. The attractively high magnetic ordering temperatures of about 270 K, underscore the importance of these materials for potential applications in spintronics.Comment: 6 page text + 5 figure

Comparative study of efficacy and safety of parenteral iron sucrose versus ferric carboxymaltose in treatment of postpartum iron deficiency anaemia

Background: Postpartum anaemia often leads to multiple clinical complications in mother as well as infant and iron supplementation with parenteral iron is the preferred treatment modality. The present study was planned to compare the efficacy and tolerability of IV iron sucrose and IV ferric carboxymaltose in treatment of postpartum iron deficiency anaemia.Methods: This randomized, parallel, open label, prospective 4-weeks study was conducted from June 2019 to December 2020 in women with postpartum anaemia admitted to obstetrics and gynaecology inpatient department of a tertiary care hospital. Women with postpartum iron deficiency anaemia (N=60) were randomly divided into two groups; receiving Injection iron sucrose (N=30, maximum dose 500 mg) or Injection ferric carboxymaltose (N=30, maximum dose 500 mg). Change in haemoglobin and serum ferritin levels from baseline to the end of 2 and 4 weeks of treatment were evaluated.Results: The results showed early, sustained and significant increase in the haemoglobin levels in both the groups. However, the difference was not significant between groups (p=0.2). Evaluation of replenishment of iron stores (serum ferritin) showed improvement in both the groups, however in FCM group the rise was found to be significant (p<0.05).Conclusions: FCM in a lower dose of 500mg was found to be safe and effective in significantly improving haemoglobin concentration as well as in replenishing iron stores in patients with postpartum anaemia

Discrete Razumikhin-type technique and stability of the Euler-Maruyama method to stochastic functional differential equations

A discrete stochastic Razumikhin-type theorem is established to investigate whether the Euler--Maruyama (EM) scheme can reproduce the moment exponential stability of exact solutions of stochastic functional differential equations (SFDEs). In addition, the Chebyshev inequality and the Borel-Cantelli lemma are applied to show the almost sure stability of the EM approximate solutions of SFDEs. To show our idea clearly, these results are used to discuss stability of numerical solutions of two classes of special SFDEs, including stochastic delay differential equations (SDDEs) with variable delay and stochastically perturbed equations