Universal asymptotic correlation functions for point group C6v\boldsymbol{C_{6v}} and an observation for triangular lattice Q\boldsymbol{Q}-state Potts model

We investigate universal forms for asymptotic correlation functions of off-critical systems that possess $C_{6v}$ symmetry following the argument for $C_{4v}$ symmetry in Phys.~Rev.~E{\bf 102},~032141. Unlike the $C_{4v}$ case, a minimal form exists that contains only two free parameters: the normalization constant and modulus. Using this form as a building block, we can construct next asymptotic forms to the minimal one. We perform large-scale Monte Carlo simulations of the triangular lattice $Q$-state Potts model above the transition temperature and successfully obtain numerical evidence to support a wide applicability of the minimal form to lattice models, including unsolvable ones. From the calculated minimal form, we derive the universal shape of equilibrium crystals in the honeycomb lattice Potts model described by an algebraic curve of genus 1. Although the curve differs from those obtained in the $C_{4v}$ case, the latters also have genus 1. We indicate that the birational equivalence concept can play an important role in comparing asymptotic forms for different point group symmetries, for example, $C_{6v}$ and $C_{4v}$.Comment: 36 pages, 4 figur

Comparison of the Efficacy of Eleven Soil Termiticides on the Formosan Subterranean Termite (Coptotermes formosanus)

Using the tunneling test, the standard test method recommended by the JWPA ( JWPS-TS-S), the minimum effective concentrations of 11 chemicals, known as major soil termiticides in Japan, were determined. Addition of the emulsifying agent, Tween 80, to the low water solubility chemicals among the termiticides yielded a 2- to 8-fold increase in their termiticidal efficacies. In contrast, addition of Tween 80 to the high water solubility chemicals produced no such enhancement of their termiticidal efficacies. In the confined test, in the case of the repellent-type chemicals of the 11 chemicals, all the test termites (10 workers and 2 soldiers) became intoxicated or paralyzed and moribund within one hour of exposure to the minimum concentration fulfilling the criteria of the JWPA standard test method. In the case of non-repellent type chemicals, all the workers became moribund within 2 hours of exposure to the minimum concentrations fulfilling the criteria of the standard test method; in contrast, it took 4 – 24 hours before the soldier termites became moribund

Effect of Hyperprolactinemia Induced by Prolactinoma (MtT/F84) on the Accessory Sexual Organs of Male Rat

A new transplantable prolactinoma, designated MtT/F84 has been serially passaged in female F344 rats. Persistently high levels of serum prolactin could be achieved in male F344 rats by MtT/F84 inoculating under the skin. This investigation deals with the effects of hyperprolactinemia upon the accessory sexual organs of male rats during puberty. The weights and the concentrations of dihydrotestosterone (DHT) in the dorsal prostate increased significantly in rats with moderate hyperprolactinemia (756 ± 179 ng/ml), but they in rats with marked hyperprolactinemia (3612 ± 1089 ng/ml) were similar t.o those of control rats. In contrast, serum testosterone levels (0.52 ± 0/17 ng/ml) in those of hyperprolactinemic rats were significantly decreased compared to that of controls (1.11± 0.13 ng/ml). These results suggested that the growth-promoting effect of prolactin on the rat prostate mediated through the action of androgen varied according to the degree of hyperprolactinemia

Effects of Lipid Peroxidation-Derived Products on the Growth of Human Colorectal Cancer Cell Line HT-29

Epidemiologic investigations indicate a close relationship between colorectal cancer and fat intake. However, to date the effects of lipid peroxidation-derived products that are formed from fat (especially free or esterified unsaturated fatty acids) on the initiation or progression of colorectal cancer have not been investigated extensively. Therefore, in the present study, we examined the effects of fatty acids, fatty acid hydroperoxides and aldehydes on the growth of human colorectal cancer cell line HT-29. At concentrations of 1 and 10 µM, linoleic, arachidonic and eicosapentaenoic acids, and 13-hydroperoxyoctadecadienoic and 15-hydroperoxyeicosapentaenoic acids had no significant effects on the growth of HT-29 cells. 4-Hydroxynonenal and 4-hydroxyhexenal had no significant effects on the growth of HT-29 cells up to 10 µM, whereas 4-oxononenal potently inhibited HT-29 cell growth (1–10 µM, 16–85% inhibition). Further experiments concerning DNA fragmentation, expression levels of Bax and Bcl-2 mRNA, expression levels of pro-caspase-3 and caspase-3 proteins, and activity of caspase-3 suggested that 4-oxononenal may increase the sensitivity of HT-29 cells to apoptosis through a decreased expression level of Bcl-2 and then increased formation of caspase-3 from pro-caspase-3

機能的腎体積測定による術後分腎機能評価の検討

PURPOSE:The change in functional renal volume (FRV) has an absolute influence on renal function after nephrectomy (Nx) or nephron-sparing surgery (NSS). In this study, we prospectively examined whether the postoperative renal function following Nx and NSS could be accurately predicted and assessed the reproducibility of our newly developed 3-D image reconstruction system (Kashihara) to measure the FRV. METHODS:We enrolled 98 patients who underwent Nx and 41 patients who underwent NSS from April 2006 to September 2009 to predict postoperative FRV and renal function. FRV was measured before and after (1 month and 1 year) renal surgery. The postoperative estimated glomerular filtration rate (eGFR) was predicted from the preoperative eGFR calculated from the serum creatinine (sCr) level and the ratio of the postoperative/preoperative FRV. To assess the reproducibility and accuracy of our newly developed 3-dimensional (3-D) image reconstruction system, FRV was measured by five examiners using images obtained by CT (five cases) and MRI (five cases). RESULTS:Significant correlation was found both for FRV and for renal function between the predictive values and the actually measured values at 1 month and 1 year after surgery, not only in the Nx group, but also in the NSS group. The accuracy and reproducibility could be confirmed both with CT and MRI studies. CONCLUSIONS:The postoperative FRV and renal function could be predicted preoperatively using a 3-D image reconstructive system, preoperative routine diagnostic imaging, and preoperative sCr level.博士（医学）・乙第1369号・平成27年11月27日© Springer-Verlag Berlin Heidelberg 2015The final publication is available at Springer via http://dx.doi.org/10.1007/s00345-014-1470-

NICU nurses' perceptions of nursing practice based on family-centered care

目的 : わが国では，1970年代終わりに新生児看護実践にfamily-centered careが取り入れられ始め，その後，family-centered developmental careの普及とともに，family-centeredであることに関心が向けられるようになった．しかし今日，NICU看護師が，自分自身のFCCに基づいた実践をどのように捉え，かつ，実践を困難にさせる理由をどのように捉えているかは十分明らかにされていない．そこで本研究では，FCCに基づいた看護実践に関するNICU看護師の認識を調査し，FCCを推進するための課題を考察することとした． 方法 : 無記名式の構成型質問紙調査を郵送法によって行った．対象者は日本新生児看護学会員674名とし，平成23年4月と平成24年5月に実施した．質問内容は，回答者の背景,FCCに基づいた看護実践，FCCに基づいた看護実践が困難な理由とした．分析は，基本統計量の算出，t検定，一元配置分散分析によって行った． 結果 : 340名から回答を得た(51.4%)．1)各基本概念の平均得点は，「心がけている」「実践している」とも，有意に「参加」が高く，「協働」が低かった．2)基本概念のいずれにおいても，「実践している」より「心がけている」の得点が有意に高かった．3)FCCに基づいた看護実践が困難な理由は，知識や実務の側面が上位を占め，最も多かったのは「医師，看護スタッフ・師長が，FCCの理念を実践化する方法を知らない」であった．4)FCCに基づいた看護実践が困難な理由は，年齢，総臨床経験年数NICU経験年数，他領域経験年数と関連した． 結論 : FCCの推進には，ガイドラインの作成および教育・訓練が重要な課題であることが考えられた．Objectives: Family-centered care was introduced into neonatal nursing practice in Japan at the end of the 1970s. It attracted much interest with the spread of family-centered development care. Today, however, what NICU nurses think about their practice based on FCC, and the reasons it is difficult to practice are not clearly understood. We therefore surveyed the perceptions of NICU nurses on nursing practice based on FCC, and discussed ways of promoting FCC. Methods: An anonymous structured question survey was sent by mail to 674 members of the Japan Academy of Neonatal Nursing in April 2011 and May 2012. Questions asked were on the respondents' background, nursing practice based on family-centered care, and reasons why practicing FCC was difficult. Data were descriptively analyzed and then a t - test and a one- way ANOVA were carried out. Results: 340 valid responses were received (51.4%). 1) Concerning practicing or being mindful of the basic concept of FCC, "participation" scored significantly highly, while the score for "collaboration" was low. 2) For all the basic concepts, the response "mindful" scored significantly higher than "practice". 3) As for the reasons why nursing practice based on FCC is difficult, most issues were related to knowledge and practice. The most frequent response was "doctors, nursing staff, and head nurses do not know how to practice the concept of FCC". 4) The difficulty of nursing practice based on FCC correlated with age and years of total clinical experience, NICU experience, and experience in other areas. Conclusion: Developing the Guidelines and providing education and training are considered necessary to promote nursing practice based on FCC.本研究は日本学術振興会科学研究費補助金基盤研究(B)22390430の助成を受けた研究の一部である