Aqua­bis(5-methyl­pyrazine-2-carboxyl­ato)zinc(II) trihydrate

In the title compound, [Zn(C6H5N2O2)2(H2O)]·3H2O, the ZnII centre is five-coordinated by two O,N-bidentate Schiff base ligands and one O atom from a water mol­ecule in a slightly distorted square-pyramidal geometry. In the crystal, the complex and uncoordinated water mol­ecules are linked by O—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds, forming a three-dimensional network

Bis(2-cyclo­hexyl­imino­methyl-4,6-dihydro­seleno­phenolato)cobalt(II) acetonitrile solvate

In the title compound, [Co(C13H16NOSe2)2]·CH3CN, the CoII atom is four-coordinated by two N,O-bidentate Schiff base ligands, resulting in a distorted tetra­hedral coordination for the metal ion

2,4-Disulfanyl-6-[(E)-(2-sulfanylbenz­yl)imino­meth­yl]phenol

In the title compound, C14H13NOS3, the dihedral angle between the benzene rings is 73.26 (5)° and an intra­molecular O—H⋯N hydrogen bond occurs

Diaqua­bis[2-(4-bromo­phen­yl)acetato]bis­(N 4,N 4-dimethyl­pyridin-4-amine)copper(II)

In the title compound, [Cu(C8H6BrO2)2(C7H10N2)2(H2O)2], the CuII atom (site symmetry ) adopts a Jahn–Teller-distorted trans-CuN2O4 octa­hedral coordination, with the aqua O atoms in axially extended sites. An intra­molecular O—H⋯O hydrogen bond helps to establish the conformation and an inter­molecular O—H⋯O hydrogen bond is seen in the crystal packing

A Relationship between vascular endothelial cell senescence and cardiovascular disease

The vascular endothelial cell (VEC) is a single layer of flat squamous epithelium covering the intima of the blood vessel. It constitutes a biological barrier to the blood vessel wall. It is not only a protective barrier but also a producer of some autocrine secretion. The substance is used to regulate homeostasis and vascular tone and has a variety of biological functions. VEC senescence can lead to vascular dysfunction, which is a major risk factor for cardiovascular system (CVS) and has a close relationship with cardiovascular disease (CVD). However, the mechanism of VEC senescence and the effects of VEC senescence on vascular function are not fully understood. This review summarizes the characteristics of VEC senescence and describes age-related CVD