583 research outputs found

    Real-time Alarm Monitoring System for Detecting Driver Fatigue in Wireless Areas

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    The purpose of this paper was to develop a real-time alarm monitoring system that can detect the fatigue driving state through wireless communication. The drivers’ electroencephalogram (EEG) signals were recorded from occipital electrodes. Seven EEG rhythms with different frequency bands as gamma, hbeta, beta, sigma, alpha, theta and delta waves were extracted. They were simultaneously assessed using relative operating characteristic (ROC) curves and grey relational analysis to select one as the fatigue feature. The research results showed that the performance of theta wave was the best one. Therefore, theta wave was used as fatigue feature in the following alarm device. The real-time alarm monitoring system based on the result has been developed, once the threshold was settled by using the data of the first ten minutes driving period. The developed system can detect driver fatigue and give alarm to indicate the onset of fatigue automatically

    Writing Instruction in China: Challenges and Efforts

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    This qualitative study examined the current writing instruction in 1-12 level education with the data collected in three Chinese cities. The data from the Interviews of teachers and teacher-educators at different levels and from classroom observations at upper elementary to high schools in three metropolitan cities across China provide insights into 1-12 writing instruction in contemporary China. To further reveal the efforts taken by writing teacher under China’s high-stakes testing culture, this paper also presented a case study of an exemplary 10th grade writing teacher, who took tremendous efforts in nurturing true readers and writers in his classroom under the test-obsessive culture in China

    Phase Fluctuation Analysis in Functional Brain Networks of Scaling EEG for Driver Fatigue Detection

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    The characterization of complex patterns arising from electroencephalogram (EEG) is an important problem with significant applications in identifying different mental states. Based on the operational EEG of drivers, a method is proposed to characterize and distinguish different EEG patterns. The EEG measurements from seven professional taxi drivers were collected under different states. The phase characterization method was used to calculate the instantaneous phase from the EEG measurements. Then, the optimization of drivers’ EEG was realized through performing common spatial pattern analysis. The structures and scaling components of the brain networks from optimized EEG measurements are sensitive to the EEG patterns. The effectiveness of the method is demonstrated, and its applicability is articulated.</p

    New Understandings of Ethanol Oxidation Reaction Mechanism on Pd/C and Pd2Ru/C Catalysts in Alkaline Direct Ethanol Fuel Cells

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    Ethanol oxidation reaction (EOR) on Pd2Ru/C and Pd/C catalysts in alkaline media is studied comprehensively by cyclic voltammetry, chronoamperometry, in situ FTIR, single fuel cell test and electrochemical impedance spectroscopy measurements. The results show that, as compared to Pd/C, Pd2Ru/C favors acetaldehyde formation and hinders its oxidation. Based on X-ray absorption data, which evidence that Ru promotes a larger electronic vacancy of the Pd 4d band, it is expected that the formation of adsorbed ethoxy is favored on Pd2Ru/C and followed by its oxidation to acetaldehyde facilitated by oxygenated species provided by Ru. In contrast, acetaldehyde oxidation is more difficult on Pd2Ru/C than on Pd/C likely because the adsorption energy of the reactive species is increased. We also show that the performance of Pd2Ru/C anode in alkaline direct ethanol fuel cell (ADEFC) is initially better but degrades much more rapidly than that with Pd/C anode under the same test conditions. The degradation is demonstrated to result from the accumulation of large amounts of acetaldehyde, which in alkaline media forms dimers by the aldol condensation reaction. The dimers tend to be responsible for blocking the active sites for further ethanol oxidation. This comprehensive study provides new understandings of the roles of Ru in Pd2Ru/C for EOR in alkaline media, unveils the causes of the performance degradation of fuel cells with Pd2Ru/C and demonstrates that initial good performances are not necessarily a valid criterion for selecting appropriate anode catalysts for ADEFC applications

    Angelica sinensis polysaccharide promotes apoptosis by inhibiting JAK/STAT pathway in breast cancer cells

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    Purpose: To determine whether Angelica polysaccharide (APS) induced apoptosis via regulation of the Janus kinase (JAK)/signal transducers and activators of transcription (STAT) pathway in breast cancer cells. Methods: Human MCF-7 cells were treated with APS. Cell proliferation, apoptosis, expression of apoptotic proteins, and the phosphorylation level of Janus kinase (JAK) and STAT were measured, respectively. For further analysis, MCF-7 cells were transfected with a JAK2 overexpression plasmid or treated with a classical JAK inhibitor, ruxolitinib. Results: Treatment with APS dose-dependently reduced cell proliferation, induced apoptosis, and downregulated the levels of phosphorylated JAK and STAT in MCF-7 cells. JAK inhibitor, ruxolitinib, blocked JAK/STAT pathway and induced cell apoptosis in MCF-7 cells. Besides, JAK2 overexpression reversed the effects of APS on cell viability and apoptosis. Conclusion: The results indicate that polysaccharide isolated from Angelica sinensis promotes apoptosis by inhibiting JAK/STAT pathway in breast cancer cells. Thus, APS may be useful as a potential therapeutic agent for breast cancer

    Preparation and analysis of sodium carboxymethyl cellulose and its effect on xerophthalmia

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    1348-1353carboxymethyl cellulose (CMC) has been effectively synthesized with high yield and purity. With the prolongation of time after model establishment, the values of Schirmer Ⅰ test (S Ⅰ t) and breakup time of tear film gradually decreased. The α-MSH and CMC alone could ameliorate corneal tissue damage and corneal morphological abnormalities in the dry eye to some extent. However, compared with monotherapy, the treatment of α-MSH combined with CMC has a more significant positive effect on the improvement of tear secretion and the stability of tear film in dry eye model in the early stage after modeling. There are significant differences between the model control group and the normal control group at each time point after model establishment (all Pth, 14th, 21th and 28th days after treatment. After 7, 14 and 21 days treatment, the S Ⅰ t values in the α-MSH+CMC treatment group were 4.80±0.79, 4.10±0.52 and 4.30±0.86 mm, respectively

    Preparation and analysis of sodium carboxymethyl cellulose and its effect on xerophthalmia

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    carboxymethyl cellulose (CMC) has been effectively synthesized with high yield and purity. With the prolongation of time after model establishment, the values of Schirmer Ⅰ test (S Ⅰ t) and breakup time of tear film gradually decreased. The α-MSH and CMC alone could ameliorate corneal tissue damage and corneal morphological abnormalities in the dry eye to some extent. However, compared with monotherapy, the treatment of α-MSH combined with CMC has a more significant positive effect on the improvement of tear secretion and the stability of tear film in dry eye model in the early stage after modeling. There are significant differences between the model control group and the normal control group at each time point after model establishment (all P&lt;0.01) at 7th, 14th, 21th and 28th days after treatment. After 7, 14 and 21 days treatment, the S Ⅰ t values in the α-MSH+CMC treatment group were 4.80±0.79, 4.10±0.52 and 4.30±0.86 mm, respectively

    Molecular dynamics simulation of helium ion implantation into silicon and its migration

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    In this paper, a model of helium ion implanted monocrystalline Si was constructed by using molecular dynamics (MD) simulation method to study the interaction mechanism of helium ion with monocrystalline Si and helium ion migration. In order to study the damage effect of helium ion implantation on monocrystalline Si, identify diamond structure (IDS), radial distribution function, temperature analysis were calculated and analyzed. The effects of ion doses, beam currents and energies on the damage were studied. Helium ion implanted Si with ion doses of 1 x 10(14)/cm(2) was subsequently heated to 300 K. MD simulation results indicated that IDS damage induced by ion implantation was positively correlated with ion doses as the ion implantation increased to 1 x 10(14)/cm(2). The mean-square displacement of helium atoms was calculated during the temperature rising to 300 K. It was found that the high permeability of helium atoms in Si and the acceleration of atomic thermal motion owing to elevated temperature as well as the existence of larger stress would be helpful to the migration of implant helium atoms.Peer reviewe
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