Regulation of intracellular free arachidonic acid in Aplysia nervous system

We have studied the regulation of arachidonic acid (AA) uptake, metabolism, and release in Aplysia nervous system. Following uptake of [ 3 H]AA, the distribution of radioactivity in intracellular and extracellular lipid pools was measured as a function of time in the presence or absence of exogenous AA. The greatest amount of AA was esterified into phosphatidylinositol (relative to pool size). We found that the intracellular free AA pool underwent rapid turnover, and that radioactive free AA and eicosanoids were released at a rapid rate into the extracellular medium, both in the presence and absence of exogenous AA. Most of the released radioactivity originated from phosphatidylinositol.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/48020/1/232_2005_Article_BF01868464.pd

X-ray detection of the most extreme star-forming galaxiesãt the cosmic noon via strong lensing

Hyperluminous infrared galaxies (HyLIRGs)ãre the most extreme star-forming systems observed in the early Universe,ãnd their properties still elude comprehensive understanding. We have undertakenã large XMM -Newton observing programme to probe the totalãccreting black hole population in three HyLIRGsãt z = 2.12, 3.25,ãnd 3.55, gravitationally lensed by foreground galaxies. Selected from the Planck All-Sky Survey to Analyse Gravitationally lensed Extreme Starbursts (PASSAGES), these HyLIRGs haveãpparent infrared luminosities > 10 14 L⊙. Our observãtions re vealed X-ray emission in each of them. PJ1336 + 49ãppears to be dominated by high-mass X-ray binaries (HMXBs). Remarkably, the luminosity of this non-AGN X-ray emission exceeds byã factor ofãbout 3 the value obtained by calibration with local galaxies with much lower star formation rates. This enhanced X-ray emission most likely highlights the efficacy of dynamical HMXB production within compact clusters, which isãn important mode of star formation in HyLIRGs. The remaining two (PJ0116 -24ãnd PJ1053 + 60) morphologicallyãnd spectrally exhibitã compact X-ray component inãddition to the extended non-AGN X-ray emission, indicating the presence of Active Galactic Nuclei (AGNs). The AGNãppears to be centrally located in the reconstructed source plane images of PJ0116 -24, which manifests its star-formingãctivity predominantly withinãn extended galactic disc. In contrast, the AGN in the field of PJ1053 + 60 is projected 60 kpcãway from the extreme star-forming galaxyãnd could be ejected from it. These results underline the synergistic potential of deep X-ray observations with strong lensing for the study of high-energyãstrophysical phenomena in HyLIRGs. © 2023 The Author(s).Open access articleThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

Predicting Psychological Distress Among Former Soviet Immigrants

This study investigated whether age, gender, marital status, education, employ ment, length of time in the U.S. and immigration demands (novelty, occupation, language, discrimination, loss, and not feeling at home) were predictors of psychological distress in a sample of 1,647 former Soviet immigrants. Multiple regression analysis indicated that the combined model of demographic and demand of immigration variables was significant. Results indicated that women, older immigrants, those with less than a college education, and those with greater immigration demands related to novelty, language, discrimination, loss, and not feeling at home were most distressed