Oxygen Tolerance in Surface-Initiated Reversible Deactivation Radical Polymerizations: Are Polymer Brushes Turning into Technology?

Over the past three decades, the development of reversible deactivation radical polymerizations (RDRP), and advancements toward more user-friendly and accessible experimental setups have opened the door for nonexperts to design complex macromolecules with well-defined properties. External mediation, improved tolerance to oxygen, and increased reaction volumes for higher synthetic output are some of the many noteworthy technical improvements. The development of RDRPs in solution was paralleled by their application on solid substrates to synthesize surface-grafted "polymer brushes" via surface-initiated RDRP (SI-RDRP). This Viewpoint paper provides a current perspective on recent developments in SI-RDRP methods that are tolerant to oxygen, especially highlighting those that could potentially enable scaling up of the synthesis of brushes for the functionalization of technologically relevant materials