4 research outputs found
ΠΡΠΎΡΠ΅ΡΡ ΡΡΠΎΡΠΎΠ°ΠΌΠΌΠΎΠ½ΠΈΠΉΠ½ΠΎΠΉ ΠΏΠ΅ΡΠ΅ΡΠ°Π±ΠΎΡΠΊΠΈ Π²ΡΡΠΎΠΊΠΎΡΡΠΎΡΠΈΡΡΡΡ Π±Π΅ΡΠΈΠ»Π»ΠΈΠ΅Π²ΡΡ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΎΠ²
Π ΡΠ°Π±ΠΎΡΠ΅ ΠΏΡΠΈΠ²Π΅Π΄Π΅Π½ΠΎ Π½Π°ΡΡΠ½ΠΎΠ΅ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΏΠΎΡΠΎΠ±Π° ΡΡΠΎΡΠΎΠ°ΠΌΠΌΠΎΠ½ΠΈΠΉΠ½ΠΎΠΉ ΠΏΠ΅ΡΠ΅ΡΠ°Π±ΠΎΡΠΊΠΈ Π²ΡΡΠΎΠΊΠΎΡΡΠΎΡΠΈΡΡΠΎΠ³ΠΎ Π±Π΅ΡΠΈΠ»Π»ΠΈΠ΅Π²ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠ°, ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½Ρ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ΅ΠΆΠΈΠΌΡ ΠΏΠ΅ΡΠ΅ΡΠ°Π±ΠΎΡΠΊΠΈ Π±Π΅ΡΠΈΠ»Π»ΠΈΠ΅Π²ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠ°. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ° ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠ΅ΠΆΠΈΠΌΠΎΠ², ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΠ²Π°ΡΡΠΈΡ
ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΠΈ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ ΠΏΠ΅ΡΠ΅ΡΠ°Π±ΠΎΡΠΊΡ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΎΠ², ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ Π½Π° ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎ ΠΈΠ·Π³ΠΎΡΠΎΠ²Π»Π΅Π½Π½ΠΎΠΉ ΠΎΠΏΡΡΠ½ΠΎΠΉ ΡΡΡΠ°Π½ΠΎΠ²ΠΊΠ΅. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΠ°Π±ΠΎΡΡ ΡΠΎΠ·Π΄Π°Π½Π° ΠΈ Π°ΠΏΡΠΎΠ±ΠΈΡΠΎΠ²Π°Π½Π° ΠΏΡΠΈΠ½ΡΠΈΠΏΠΈΠ°Π»ΡΠ½Π°Ρ ΡΡ
Π΅ΠΌΠ° ΠΏΠ΅ΡΠ΅ΡΠ°Π±ΠΎΡΠΊΠΈ Π±Π΅ΡΠΈΠ»Π»ΠΈΠ΅Π²ΡΡ
ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΎΠ², ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½ΠΎ Π°ΠΏΠΏΠ°ΡΠ°ΡΡΡΠ½ΠΎΠ΅ ΠΎΡΠΎΡΠΌΠ»Π΅Π½ΠΈΠ΅ ΠΏΡΠΎΡΠ΅ΡΡΠ°. ΠΡΠΈΠ²Π΅Π΄Π΅Π½ΠΎ ΡΠ΅Ρ
Π½ΠΈΠΊΠΎ-ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΠΈ.The scientific substantiation of the processing of high-fluoride beryllium concentrates by ammonium fluoride is given in graduation thesis. Technological conditions of beryllium concentrate processing are proposed. The research of the technological process and determination of the conditions providing cost-effective processing of concentrates was carried out on a specially manufactured pilot plant. As a result of the work, a basic scheme for the processing of beryllium concentrates was developed and approved, and the hardware design of the process was developed. The feasibility study of technology is shown
Mechanismen der Restenosierung nach koronarer Stentimplantation : ein Paargruppenvergleich zwischen Diabetikern und Nicht-Diabetikern
Diabetes mellitus is an established risk factor for stent restenosis, in part as a result of smaller vessel dimensions and longer lesions. Aim of this study was to compare the magnitude of acute lumen gain and late lumen loss after elective coronary stent implantation in diabetic and non-diabetic patients using a matched-pair analysis. A total of 133 diabetic patients with 192 coronary lesions were included into this analysis. From a database of 993 non-diabetic patients, a group of 192 lesions in 182 non-diabetic patients were matched in a pairwise fashion stratifying for reference diameter (RD), minimal lumen diameter (MLD) and lesion length (LL). All patients underwent a follow-up angiography (FUA) 5Β±2 month post intervention. Preinterventional baseline angiographic matching variables as well as mean stent length, stent diameter, and maximal implantation pressure were not different. The binary restenosis rate at 5 month FUA was 25% in the diabetes group and 14% in the non-diabetes group (p<0.01). Both, acute angiographic lumen gain (1.47Β±0.41 vs. 1.56Β±0.38mm, p=0.03), as well as late lumen loss (0.64Β±0.42 vs. 0.55Β±0.36mm, p=0.02) were significantly different between diabetic and non-diabetic patients. Suboptimal acute procedural results and the exaggerated neointimal proliferation contributed by about 50% to the lower net lumen gain in diabetic patients. Patients with diabetes mellitus show a significantly higher restenosis rate even if matched for preprocedural angiographic lesion dimensions. Mechanistically, inferior procedural results as well as exaggerated neointimal proliferation are quantitatively equally important for this process
Mechanismen der Restenosierung nach koronarer Stentimplantation : ein Paargruppenvergleich zwischen Diabetikern und Nicht-Diabetikern
Diabetes mellitus is an established risk factor for stent restenosis, in part as a result of smaller vessel dimensions and longer lesions. Aim of this study was to compare the magnitude of acute lumen gain and late lumen loss after elective coronary stent implantation in diabetic and non-diabetic patients using a matched-pair analysis. A total of 133 diabetic patients with 192 coronary lesions were included into this analysis. From a database of 993 non-diabetic patients, a group of 192 lesions in 182 non-diabetic patients were matched in a pairwise fashion stratifying for reference diameter (RD), minimal lumen diameter (MLD) and lesion length (LL). All patients underwent a follow-up angiography (FUA) 5Β±2 month post intervention. Preinterventional baseline angiographic matching variables as well as mean stent length, stent diameter, and maximal implantation pressure were not different. The binary restenosis rate at 5 month FUA was 25% in the diabetes group and 14% in the non-diabetes group (p<0.01). Both, acute angiographic lumen gain (1.47Β±0.41 vs. 1.56Β±0.38mm, p=0.03), as well as late lumen loss (0.64Β±0.42 vs. 0.55Β±0.36mm, p=0.02) were significantly different between diabetic and non-diabetic patients. Suboptimal acute procedural results and the exaggerated neointimal proliferation contributed by about 50% to the lower net lumen gain in diabetic patients. Patients with diabetes mellitus show a significantly higher restenosis rate even if matched for preprocedural angiographic lesion dimensions. Mechanistically, inferior procedural results as well as exaggerated neointimal proliferation are quantitatively equally important for this process