921 research outputs found
Simulation of merging binary neutron stars in full general relativity: case
We have performed 3D numerical simulations for merger of equal mass binary
neutron stars in full general relativity. We adopt a -law equation of
state in the form where P, , \varep and
are the pressure, rest mass density, specific internal energy, and the
adiabatic constant with . As initial conditions, we adopt models of
corotational and irrotational binary neutron stars in a quasi-equilibrium state
which are obtained using the conformal flatness approximation for the three
geometry as well as an assumption that a helicoidal Killing vector exists. In
this paper, we pay particular attention to the final product of the
coalescence. We find that the final product depends sensitively on the initial
compactness parameter of the neutron stars : In a merger between sufficiently
compact neutron stars, a black hole is formed in a dynamical timescale. As the
compactness is decreased, the formation timescale becomes longer and longer. It
is also found that a differentially rotating massive neutron star is formed
instead of a black hole for less compact binary cases, in which the rest mass
of each star is less than 70-80% of the maximum allowed mass of a spherical
star. In the case of black hole formation, we roughly evaluate the mass of the
disk around the black hole. For the merger of corotational binaries, a disk of
mass may be formed, where M_* is the total rest mass of the
system. On the other hand, for the merger of irrotational binaries, the disk
mass appears to be very small : < 0.01M_*.Comment: 27 pages, to appear in Phys. Rev.
Nonlinear atom optics and bright gap soliton generation in finite optical lattices
We theoretically investigate the transmission dynamics of coherent matter
wave pulses across finite optical lattices in both the linear and the nonlinear
regimes. The shape and the intensity of the transmitted pulse are found to
strongly depend on the parameters of the incident pulse, in particular its
velocity and density: a clear physical picture for the main features observed
in the numerical simulations is given in terms of the atomic band dispersion in
the periodic potential of the optical lattice. Signatures of nonlinear effects
due the atom-atom interaction are discussed in detail, such as atom optical
limiting and atom optical bistability. For positive scattering lengths, matter
waves propagating close to the top of the valence band are shown to be subject
to modulational instability. A new scheme for the experimental generation of
narrow bright gap solitons from a wide Bose-Einstein condensate is proposed:
the modulational instability is seeded in a controlled way starting from the
strongly modulated density profile of a standing matter wave and the solitonic
nature of the generated pulses is checked from their shape and their
collisional properties
Risk factors for high anti-HHV-8 antibody titers (â„1:51,200) in black, HIV-1 negative South African cancer patients: a case control study
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the
development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase
risk for KS. However, the geographic distribution of HHV-8 and KS both prior to the HIV/AIDS
epidemic and with HIV/AIDS suggest the presence of an additional co-factor in the development of
KS.
Methods: Between January 1994 and October 1997, we interviewed 2576 black in-patients with
cancer in Johannesburg and Soweto, South Africa. Blood was tested for antibodies against HIV-1
and HHV-8 and the study was restricted to 2191 HIV-1 negative patients. Antibodies against the
latent nuclear antigen of HHV-8 encoded by orf73 were detected with an indirect
immunofluorescence assay. We examined the relationship between high anti-HHV-8 antibody
titers (â„1:51,200) and sociodemographic and behavioral factors using unconditional logistic
regression models. Variables that were significant at p = 0.10 were included in multivariate analysis.
Results: Of the 2191 HIV-1 negative patients who did not have Kaposi's sarcoma, 854 (39.0%)
were positive for antibodies against HHV-8 according to the immunofluorescent assay. Among
those seropositive for HHV-8, 530 (62.1%) had low titers (1:200), 227 (26.6%) had medium titers
(1:51,200) and 97 (11.4%) had highest titers (1:204,800). Among the 2191 HIV-1 negative patients,
the prevalence of high anti-HHV-8 antibody titers (â„1:51,200) was independently associated with
increasing age (ptrend = 0.04), having a marital status of separated or divorced (p = 0.003), using
wood, coal or charcoal as fuel for cooking 20 years ago instead of electricity (p = 0.02) and
consuming traditional maize beer more than one time a week (p = 0.02; p-trend for increasing
consumption = 0.05) although this may be due to chance given the large number of predictors
considered in this analysis.
Conclusions: Among HIV-negative subjects, patients with high anti-HHV-8 antibody titers are
characterized by older age. Other associations that may be factors in the development of high anti-
HHV-8 titers include exposure to poverty or a low socioeconomic status environment and
consumption of traditional maize beer. The relationship between these variables and high anti-
HHV-8 titers requires further, prospective study
Phenotypic covariance of longevity, immunity and stress resistance in the Caenorhabditis nematodes
Background \ud
Ageing, immunity and stresstolerance are inherent characteristics of all organisms. In animals, these traits are regulated, at least in part, by forkhead transcription factors in response to upstream signals from the Insulin/Insulinâ like growth factor signalling (IIS) pathway. In the nematode Caenorhabditis elegans, these phenotypes are molecularly linked such that activation of the forkhead transcription factor DAF-16 both extends lifespan and simultaneously increases immunity and stress resistance. It is known that lifespan varies significantly among the Caenorhabditis species but, although DAF-16 signalling is highly conserved, it is unclear whether this phenotypic linkage occurs in other species. Here we investigate this phenotypic covariance by comparing longevity, stress resistance and immunity in four \ud
Caenorhabditis species. \ud
\ud
Methodology/Principal Findings \ud
We show using phenotypic analysis of DAF-16 influenced phenotypes that among four closely related Caenorhabditis nematodes, the gonochoristic species (Caenorhabditis remanei and Caenorhabditis brenneri) have diverged \ud
significantly with a longer lifespan, improved stress resistance and higher immunity than the hermaphroditic species (C. elegans and Caenorhabditis briggsae). Interestingly, we also observe significant differences in expression levels between the daf-16 homologues in these species using Real-Time PCR, which positively correlate with the observed phenotypes. Finally, we provide additional evidence in support of a role for DAF-16 in regulating phenotypic coupling by using a combination of wildtype isolates, constitutively active daf-16 mutants and bioinformatic analysis. \ud
\ud
Conclusions \ud
The gonochoristic species display a significantly longer lifespan (p < 0.0001)and more robust immune and stress response (p<0.0001, thermal stress; p<0.01, heavy metal stress; p<0.0001, pathogenic stress) than the hermaphroditic species. Our data suggests that divergence in DAF-16 mediated phenotypes may underlie many of the differences observed between these four species of Caenorhabditis nematodes. These findings are further supported by the correlative higher daf-16 expression levels among the gonochoristic species and significantly higher lifespan, immunity and stress tolerance in the constitutively active daf-16 hermaphroditic mutants
Phenotypic covariance of Longevity, Immunity and Stress Resistance in the Caenorhabditis Nematodes
Background: Ageing, immunity and stresstolerance are inherent characteristics of all organisms. In animals, these traits are regulated, at least in part, by forkhead transcription factors in response to upstream signals from the Insulin/Insulinâlike growth factor signalling (IIS) pathway. In the nematode Caenorhabditis elegans, these phenotypes are molecularly linked such that activation of the forkhead transcription factor DAF-16 both extends lifespan and simultaneously increases immunity and stress resistance. It is known that lifespan varies significantly among the Caenorhabditis species but, although DAF-16 signalling is highly conserved, it is unclear whether this phenotypic linkage occurs in other species. Here we investigate this phenotypic covariance by comparing longevity, stress resistance and immunity in four Caenorhabditis species. \ud
\ud
Methodology/Principal Findings: We show using phenotypic analysis of DAF-16 influenced phenotypes that among four closely related Caenorhabditis nematodes, the gonochoristic species (Caenorhabditis remanei and Caenorhabditis brenneri) have diverged significantly with a longer lifespan, improved stress resistance and higher immunity than the hermaphroditic species (C. elegans and Caenorhabditis briggsae). Interestingly, we also observe significant differences in expression levels between the daf-16 homologues in these species using Real-Time PCR, which positively correlate with the observed phenotypes. Finally, we provide additional evidence in support of a role for DAF-16 in regulating phenotypic coupling by using a combination of wildtype isolates, constitutively active daf-16 mutants and bioinformatic analysis. \ud
\ud
Conclusions: The gonochoristic species display a significantly longer lifespan (p<0.0001) and more robust immune and stress response (p<0.0001, thermal stress; p<0.01, heavy metal stress; p<0.0001, pathogenic stress) than the hermaphroditic species. Our data suggests that divergence in DAF-16 mediated phenotypes may underlie many of the differences observed between these four species of Caenorhabditis nematodes. These findings are further supported by the correlative higher daf-16 expression levels among the gonochoristic species and significantly higher lifespan, immunity and stress tolerance in the constitutively active daf-16 hermaphroditic mutants
Regularity Properties and Pathologies of Position-Space Renormalization-Group Transformations
We reconsider the conceptual foundations of the renormalization-group (RG)
formalism, and prove some rigorous theorems on the regularity properties and
possible pathologies of the RG map. Regarding regularity, we show that the RG
map, defined on a suitable space of interactions (= formal Hamiltonians), is
always single-valued and Lipschitz continuous on its domain of definition. This
rules out a recently proposed scenario for the RG description of first-order
phase transitions. On the pathological side, we make rigorous some arguments of
Griffiths, Pearce and Israel, and prove in several cases that the renormalized
measure is not a Gibbs measure for any reasonable interaction. This means that
the RG map is ill-defined, and that the conventional RG description of
first-order phase transitions is not universally valid. For decimation or
Kadanoff transformations applied to the Ising model in dimension ,
these pathologies occur in a full neighborhood of the low-temperature part of the first-order
phase-transition surface. For block-averaging transformations applied to the
Ising model in dimension , the pathologies occur at low temperatures
for arbitrary magnetic-field strength. Pathologies may also occur in the
critical region for Ising models in dimension . We discuss in detail
the distinction between Gibbsian and non-Gibbsian measures, and give a rather
complete catalogue of the known examples. Finally, we discuss the heuristic and
numerical evidence on RG pathologies in the light of our rigorous theorems.Comment: 273 pages including 14 figures, Postscript, See also
ftp.scri.fsu.edu:hep-lat/papers/9210/9210032.ps.
Relativistic quantum transport theory of hadronic matter: the coupled nucleon, delta and pion system
We derive the relativistic quantum transport equation for the pion
distribution function based on an effective Lagrangian of the QHD-II model. The
closed time-path Green's function technique, the semi-classical, quasi-particle
and Born approximation are employed in the derivation. Both the mean field and
collision term are derived from the same Lagrangian and presented analytically.
The dynamical equation for the pions is consistent with that for the nucleons
and deltas which we developed before. Thus, we obtain a relativistic transport
model which describes the hadronic matter with , and degrees
of freedom simultaneously. Within this approach, we investigate the medium
effects on the pion dispersion relation as well as the pion absorption and pion
production channels in cold nuclear matter. In contrast to the results of the
non-relativistic model, the pion dispersion relation becomes harder at low
momenta and softer at high momenta as compared to the free one, which is mainly
caused by the relativistic kinetics. The theoretically predicted free cross section is in agreement with the experimental data. Medium
effects on the cross section and momentum-dependent
-decay width are shown to be substantial.Comment: 66 pages, Latex, 12 PostScript figures included; replaced by the
revised version, to appear in Phys. Rev.
Quality and Safety Aspects of Infant Nutrition
Quality and safety aspects of infant nutrition are of key importance for child health, but oftentimes they do not get much attention by health care professionals whose interest tends to focus on functional benefits of early nutrition. Unbalanced diets and harmful food components induce particularly high risks for untoward effects in infants because of their rapid growth, high nutrient needs, and their typical dependence on only one or few foods during the first months of life. The concepts, standards and practices that relate to infant food quality and safety were discussed at a scientific workshop organized by the Child Health Foundation and the Early Nutrition Academy jointly with the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, and a summary is provided here. The participants reviewed past and current issues on quality and safety, the role of different stakeholders, and recommendations to avert future issues. It was concluded that a high level of quality and safety is currently achieved, but this is no reason for complacency. The food industry carries the primary responsibility for the safety and suitability of their products, including the quality of composition, raw materials and production processes. Introduction of new or modified products should be preceded by a thorough science based review of suitability and safety by an independent authority. Food safety events should be managed on an international basis. Global collaboration of food producers, food-safety authorities, paediatricians and scientists is needed to efficiently exchange information and to best protect public health. Copyright (C) 2012 S. Karger AG, Base
Bosonic representation of one-dimensional Heisenberg ferrimagnets
The energy structure and the thermodynamics of ferrimagnetic Heisenberg
chains of alternating spins S and s are described in terms of the Schwinger
bosons and modified spin waves. In the Schwinger representation, we average the
local constraints on the bosons and diagonalize the Hamiltonian at the
Hartree-Fock level. In the Holstein-Primakoff representation, we optimize the
free energy in two different ways introducing an additional constraint on the
staggered magnetization. A new modified spin-wave scheme, which employs a
Lagrange multiplier keeping the native energy structure free from temperature
and thus differs from the original Takahashi Scheme, is particularly stressed
as an excellent language to interpret one-dimensional quantum ferrimagnetism.
Other types of one-dimensional ferrimagnets and the antiferromagnetic limit S=s
are also mentioned.Comment: to be published in Phys. Rev. B 69, No. 6, 0644XX (2004
Inclusive Search for Anomalous Production of High-pT Like-Sign Lepton Pairs in Proton-Antiproton Collisions at sqrt{s}=1.8 TeV
We report on a search for anomalous production of events with at least two
charged, isolated, like-sign leptons with pT > 11 GeV/c using a 107 pb^-1
sample of 1.8 TeV ppbar collisions collected by the CDF detector. We define a
signal region containing low background from Standard Model processes. To avoid
bias, we fix the final cuts before examining the event yield in the signal
region using control regions to test the Monte Carlo predictions. We observe no
events in the signal region, consistent with an expectation of
0.63^(+0.84)_(-0.07) events. We present 95% confidence level limits on new
physics processes in both a signature-based context as well as within a
representative minimal supergravity (tanbeta = 3) model.Comment: 15 pages, 4 figures. Minor textual changes, cosmetic improvements to
figures and updated and expanded reference
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