778 research outputs found
Letter, 1952 September 24, from Warren S. Freeman to Carson Robison
1 page, Freeman is a representative of Record Industry Association
Critical study of music education in the state teachers colleges of Massachusetts
Thesis (M.A.)--Boston University, 1937. This item was digitized by the Internet Archive
A survey and evaluation of the current status of music education activities in public schools of the United States
Thesis (Ed.D.)--Boston Universit
Critical study of music education in the state teachers colleges of Massachusetts
Thesis (M.A.)--Boston University, 1937. This item was digitized by the Internet Archive
Targeted Assembly of Short Sequence Reads
As next-generation sequence (NGS) production continues to increase, analysis is becoming a significant bottleneck. However, in situations where information is required only for specific sequence variants, it is not necessary to assemble or align whole genome data sets in their entirety. Rather, NGS data sets can be mined for the presence of sequence variants of interest by localized assembly, which is a faster, easier, and more accurate approach. We present TASR, a streamlined assembler that interrogates very large NGS data sets for the presence of specific variants, by only considering reads within the sequence space of input target sequences provided by the user. The NGS data set is searched for reads with an exact match to all possible short words within the target sequence, and these reads are then assembled strin-gently to generate a consensus of the target and flanking sequence. Typically, variants of a particular locus are provided as different target sequences, and the presence of the variant in the data set being interrogated is revealed by a successful assembly outcome. However, TASR can also be used to find unknown sequences that flank a given target. We demonstrate that TASR has utility in finding or confirming ge-nomic mutations, polymorphism, fusion and integration events. Targeted assembly is a powerful method for interrogating large data sets for the presence of sequence variants of interest. TASR is a fast, flexible and easy to use tool for targeted assembly
Bostonia: The Boston University Alumni Magazine. Volume 20
Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs
Implementation of NMR quantum computation with para-hydrogen derived high purity quantum states
We demonstrate the first implementation of a quantum algorithm on a liquid
state nuclear magnetic resonance (NMR) quantum computer using almost pure
states. This was achieved using a two qubit device where the initial state is
an almost pure singlet nuclear spin state of a pair of 1H nuclei arising from a
chemical reaction involving para-hydrogen. We have implemented Deutsch's
algorithm for distinguishing between constant and balanced functions with a
single query.Comment: 7 pages RevTex including 6 figures. Figures 4-6 are low quality to
save space. Submitted to Phys Rev
Dynamical suppression of unwanted transition paths in multistate quantum systems
We introduce a method to suppress unwanted transition channels, even without
knowing their couplings, and achieve perfect population transfer in multistate
quantum systems by the application of composite pulse sequences. Unwanted
transition paths may be present due to imperfect light polarization, stray
electromagnetic fields, misalignment of quantization axis, spatial
inhomogeneity of trapping fields, off-resonant couplings, etc. Compensation of
simultaneous deviations in polarization, pulse area, and detuning is
demonstrated. The accuracy, the flexibility and the robustness of this
technique make it suitable for high-fidelity applications in quantum optics and
quantum information processing.Comment: 5 figure
Less than 50% sublattice polarization in an insulating S=3/2 kagome' antiferromagnet at low T
We have found weak long range antiferromagnetic order in the
quasi-two-dimensional insulating oxide which contains
Cr S=3/2 ions on a kagom\'{e} lattice. In a sample with 76%
occupancy of the chromium sites the ordered moment is 1.1(3) per
chromium ion which is only one third of the N\'{e}el value .
The magnetic unit cell equals the chemical unit cell, a situation which is
favored by inter-plane interactions. Gapless quantum spin-fluctuations
(T_NS(Q,\omega)$ in the ordered
phase.Comment: 18 pages, RevTex/Latex, with 6 figure
Snapshot PCR surveillance for SARS-CoV-2 in hospital staff in England
Background: Significant nosocomial transmission of SARS-CoV-2 has been demonstrated. Understanding the prevalence of SARS-CoV-2 carriage amongst HCWs at work is necessary to inform the development of HCW screening programmes to control nosocomial spread. /
Methods: Cross-sectional ‘snapshot’ survey from April-May 2020; HCWs recruited from six UK hospitals. Participants self-completed a health questionnaire and underwent a combined viral nose and throat swab, tested by Polymerase Chain Reaction (PCR) for SARS-CoV-2 with viral culture on majority of positive samples. /
Findings: Point prevalence of SARS-CoV-2 carriage across the sites was 2.0% (23/1152 participants), median cycle threshold value 35.70 (IQR:32.42–37.57). 17 were previously symptomatic, two currently symptomatic (isolated anosmia and sore throat); the remainder declared no prior or current symptoms. Symptoms in the past month were associated with threefold increased odds of testing positive (aOR 3.46, 95%CI 1.38–8.67; p = 0.008). SARS-CoV-2 virus was isolated from only one (5%) of nineteen cultured samples. A large proportion (39%) of participants reported symptoms in the past month. /
Interpretation: The point-prevalence is similar to previous estimates for HCWs in April 2020, though a magnitude higher than in the general population. Based upon interpretation of symptom history and testing results including viral culture, the majority of those testing positive were unlikely to be infectious at time of sampling. Development of screening programmes must balance the potential to identify additional cases based upon likely prevalence, expanding the symptoms list to encourage HCW testing, with resource implications and risks of excluding those unlikely to be infectious with positive tests. /
Funding: Public Health England
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