Proton beam therapy causing pericarditis - a rare case of radiation induced cardiotoxicity.

Acute pericarditis is caused by the inflammation of the pericardium which can result in an effusion around the heart. Proton beam therapy causing radiation-induced pericarditis is not a well-known cause of pericarditis. We present a case of a patient with Li-Fraumeni Syndrome who developed acute onset pericarditis, presumed to be secondary to proton beam therapy

Towards a Big Crunch Dual

We show there exist smooth asymptotically anti-de Sitter initial data which evolve to a big crunch singularity in a low energy supergravity limit of string theory. This opens up the possibility of using the dual conformal field theory to obtain a fully quantum description of the cosmological singularity. A preliminary study of this dual theory suggests that the big crunch is an endpoint of evolution even in the full string theory. We also show that any theory with scalar solitons must have negative energy solutions. The results presented here clarify our earlier work on cosmic censorship violation in N=8 supergravity.Comment: 27 pages, 3 figures;v2:minor correction

Negative Energy in String Theory and Cosmic Censorship Violation

We find asymptotically anti de Sitter solutions in N=8 supergravity which have negative total energy. This is possible since the boundary conditions required for the positive energy theorem are stronger than those required for finite mass (and allowed by string theory). But stability of the anti de Sitter vacuum is still ensured by the positivity of a modified energy, which includes an extra surface term. Some of the negative energy solutions describe classical evolution of nonsingular initial data to naked singularities. Since there is an open set of such solutions, cosmic censorship is violated generically in supergravity. Using the dual field theory description, we argue that these naked singularities will be resolved in the full string theory.Comment: 23 pages, 2 figures, v2: argument for forming naked singularities clarified, references adde

Surprising Connections Between General Relativity and Condensed Matter

This brief review is intended to introduce gravitational physicists to recent developments in which general relativity is being used to describe certain aspects of condensed matter systems, e.g., superconductivity.Comment: 14 pages; based on talk given at GR1

Writing CFT correlation functions as AdS scattering amplitudes

We explore the Mellin representation of conformal correlation functions recently proposed by Mack. Examples in the AdS/CFT context reinforce the analogy between Mellin amplitudes and scattering amplitudes. We conjecture a simple formula relating the bulk scattering amplitudes to the asymptotic behavior of Mellin amplitudes and show that previous results on the flat space limit of AdS follow from our new formula. We find that the Mellin amplitudes are particularly useful in the case of conformal gauge theories in the planar limit. In this case, the four point Mellin amplitudes are meromorphic functions whose poles and their residues are entirely determined by two and three point functions of single-trace operators. This makes the Mellin amplitudes the ideal objects to attempt the conformal bootstrap program in higher dimensions.Comment: 23 pages + appendice

Spacetime in String Theory

We give a brief overview of the nature of spacetime emerging from string theory. This is radically different from the familiar spacetime of Einstein's relativity. At a perturbative level, the spacetime metric appears as ``coupling constants" in a two dimensional quantum field theory. Nonperturbatively (with certain boundary conditions), spacetime is not fundamental but must be reconstructed from a holographic, dual theory.Comment: 20 pages; references adde

On Feynman rules for Mellin amplitudes in AdS/CFT

The computation of CFT correlation functions via Witten diagrams in AdS space can be simplified via the Mellin transform. Recently a set of Feynman rules for tree-level Mellin space amplitudes has been proposed for scalar theories. In this note we derive these rules by explicitly evaluating all of the relevant Witten diagram integrals for the scalar phi^n theory. We also check that the rules reduce to the usual Feynman rules in the flat space limit.Comment: minor corrections, published versio