What Rises Above the White Noise: the Possibility of Hearing Truth in a Post-truth World

This installation in a valley in the UK’s Lake District National Park taps into the idea of communication, the problem of apparent fact and post-truth, and which voices are being heard when it comes to standing up for the environment. In consideration of post-truth and the confusion between fact and fiction, particularly with regard to issues about environment, this art installation explores the possibility of clarity in voices that are heard above the white noise of facts, partial truths and information overload. It is a site-specific installation, created around a single tree and a rapidly flowing river in the Lake District National Park, where many different organizations strive for balance between human occupation and natural biodiversity, and not everyone feels their voices are heard or adequately acted upon

Cell lineage analysis of the avian neural crest

Neural crest cells migrate extensively and give rise to diverse cell types, including cells of the sensory and autonomic nervous systems. A major unanswered question concerning the neural crest is when and how the neural crest cells become determined to adopt a particular fate. We have explored the developmental potential of trunk neural crest cells in avian embryos by microinjecting a vital dye, lysinated rhodamine dextran (LRD), into individual cells within the dorsal neural tube. We find that premigratory and emigrating neural crest cells give rise to descendants with distinct phenotypes in multiple neural crest derivatives. These results are consistent with the idea that neural crest cells are multipotent prior to their emigration from the neural tube and become restricted in phenotype after emigration from the neural tube either during their migration or at their sites of localization. To determine whether neural crest cells become restricted during their migration, we have microinjected individual trunk neural crest cells with dye shortly after they leave the neural tube or as they migrate through the somite. We find that a majority of the clones derived from migrating neural crest cells appear to be multipotent; individual migrating neural crest cells gave rise to both sensory and sympathetic neurons, as well as cells with the morphological characteristics of Schwann cells, and other nonneuronal cells. Even those clones contributing to only one neural crest derivative often contained both neurofilament-positive and neurofilament-negative cells. These data demonstrate that migrating trunk neural crest cells, like their premigratory progenitors, can be multipotent. They give rise to cells in multiple neural crest derivatives and contribute to both neuronal and non-neuronal elements within a given derivative. Thus, restriction of neural crest cell fate must occur relatively late in migration or at the final destinations

Migrating neural crest cells in the trunk of the avian embryo are multipotent

Trunk neural crest cells migrate extensively and give rise to diverse cell types, including cells of the sensory and autonomic nervous systems. Previously, we demonstrated that many premigratory trunk neural crest cells give rise to descendants with distinct phenotypes in multiple neural crest derivatives. The results are consistent with the idea that neural crest cells are multipotent prior to their emigration from the neural tube and become restricted in phenotype after leaving the neural tube either during their migration or at their sites of localization. Here, we test the developmental potential of migrating trunk neural crest cells by microinjecting a vital dye, lysinated rhodamine dextran (LRD), into individual cells as they migrate through the somite. By two days after injection, the LRD-labelled clones contained from 2 to 67 cells, which were distributed unilaterally in all embryos. Most clones were confined to a single segment, though a few contributed to sympathetic ganglia over two segments. A majority of the clones gave rise to cells in multiple neural crest derivatives. Individual migrating neural crest cells gave rise to both sensory and sympathetic neurons (neurofilament-positive), as well as cells with the morphological characteristics of Schwann cells, and other non-neuronal cells (both neurofilament-negative). Even those clones contributing to only one neural crest derivative often contained both neurofilament-positive and neurofilament-negative cells. Our data demonstrate that migrating trunk neural crest cells can be multipotent, giving rise to cells in multiple neural crest derivatives, and contributing to both neuronal and non-neuronal elements within a given derivative. Thus, restriction of neural crest cell fate must occur relatively late in migration or at the final sites of neural crest cell localization

On the Genealogy of Universals: The Metaphysical Origins of Analytic Philosophy

The concepts of particular and universal have grown so familiar that their significance has become difficult to discern, like coins that have been passed back and forth too many times, worn smooth so their values can no longer be read. On the Genealogy of Universals seeks to overcome our sense of over-familiarity with these concepts by providing a case study of their evolution during the late nineteenth century and early twentieth century, a study that shows how the history of these concepts is bound up with the origins and development of analytic philosophy itself. Understanding how these concepts were taken up, transfigured, and given up by the early analytic philosophers, enables us to recover and reanimate the debate amongst them that otherwise remains Delphic. This book begins from the early, originating texts of analytic philosophy that have hitherto baffled commentators, including Moore's early papers, and engages afresh with the neglected contributions of philosophical figures that historians of analytic philosophy have mostly since forgotten, including Stout and Whitehead. This sheds new light upon the relationships of Moore to Russell, Russell to Wittgenstein, and Wittgenstein to Ramsey

Beyond definition: Organising semantic information in bilingual dictionaries

This paper considers the process of organising semantic information in bilingual dictionaries with diachronic coverage, from selecting the textual source-material to designing the entries. The discussion centres on practical aspects of ancient Greek lexicography. First, the traditional semantic frameworks are described. Then, more recent approaches are noted, notably those of Adrados and of Chadwick, both of which aim to integrate contextual data within a semantic framework. Since the relevance of contextual information varies with lemma part of speech, different configurations are required for entries describing nouns, adjectives, and verbs. These are illustrated by three entries from a Greek-English dictionary currently being written at Cambridge. In order to organise data to this level of specificity, stylistic templates are indispensable, and digital software provides a means of providing them. However, systems designed for writing new dictionaries require different features from those designed for encoding pre-existing texts. A description is given of how the lexicographic requirements of the Cambridge dictionary were met by a user-designed system

Women and the art of fiction

Women wrote about art in the nineteenth century in a variety of genres, ranging from the formal historical or technical treatise and professional art journalism, to travel writing, poetry, and fiction. Their fiction is often less ideologically circumscribed than their formal art histories: the visual arts constituted a language for writing about the social position of women, and about questions of gender and sexuality. This essay considers how women introduced the visual arts and artist figures into their fiction in critically distinctive ways, and can be said in this form to have contributed to nineteenth-century art discourse and debate