Subgroup analyses of the performance of the machine-learned predictor.

Subgroup analyses of the performance of the machine-learned predictor.</p

2x2 contingency Tables & additional statistics.

(DOCX)</p

STARD checklist.

(DOCX)</p

Histogram of study population LVEDP.

Histogram of study population LVEDP.</p

Performance of the machine-learned predictor.

Performance of the machine-learned predictor.</p

Feature values.

(XLSX)</p

Propensity matching.

(DOCX)</p

Relationship between pre-test (prior) probability and post-test (posterior) probabilities.

a) the machine-learned predictor, b) BNP when greater than 150pg/ml, or c) BNP when greater than 50pg/ml. A positive test is shown in red, and a negative test in green. The diagonal dashed black line represents no change from the pre-test to post-test probability. The vertical dashed black lines represent intermediate to high pre-test probabilities (vertical dashed lines at 30%, 50% and 70%) from left to right. The post-test probabilities were calculated based on a varying pre-test probability, and constant sensitivity, specificity, and corresponding likelihood ratios.</p

Inclusion and exclusion criteria.

(DOCX)</p

Performance of the machine-learned model when propensity matching based on age and gender.

Performance of the machine-learned model when propensity matching based on age and gender.</p