A CDSS Supporting Clinical Guidelines Integrated and Interoperable Within the Clinical Information System

International audienc

Compte de résultat analytique d'une unité périopératoire gériatrique

International audienceAim: Hip fracture management in a dedicated geriatric periopera-tive unit improves long-term mortality. In this study, we report the health economics evaluation of this geriatric perioperative care unit (UPOG). Methods: This study was conducted in 2011. Direct expenditures were obtained from the Assistance Publique-Hôpitaux de Paris database, indirect expenditures from the hospital cost accounting, and financial incomes from the PMSI Pilot programme. Emergency department incomes and expenditures were estimated together with additional incomes related to orthopaedic surgery. We estimated expenditures related to operating room (OR) activities in the framework of several models, one with an emergency OR open 24h/24, and one with a standard OR. Lastly, we compared incomes/expenditures according to regular paramedical staff or according to the paramedical staff that would appear to be necessary to ensure patient care. Results: 253 patients were admitted to the UPOG during the study, 215 (84%) of whom underwent surgery. The income statement was positive for both an emergency OR (+741,000 Euros) and a standard OR (+490,000 Euros) and remained positive when para-medical staff was increased (+629,000 and +156,000 Euros, respectively). Conclusion: The UPOG income statement shows a positive result regardless of the model used, emergency 24h/24 OR or standard OR, and even when paramedical staff is increased.Objectif : La prise en charge précoce des fractures du col du fémur dans une unité périopératoire de gériatrie (UPOG) a démontré son efficacité sur la mortalité à long terme. Dans cette étude, nous avons évalué médico-économiquement une UPOG. Méthodes : L'année 2011 a été évaluée. Les dépenses directes ont été obtenues à partir de la banque de données de l' Assistance publique-Hôpitaux de Paris, les dépenses indirectes à partir du compte de résultat analytique de l'hôpital, et les recettes à partir des groupes homogènes de séjour de PMSI Pilot. Recettes et dépenses aux urgences ont été estimées ainsi que les recettes supplémentaires induites dans le service de chirurgie ortho-pédique. Nous avons estimé les dépenses liées à l'activité opératoire dans le cadre de plusieurs modèles, celui d'un bloc d'urgence ouvert 24 h/24 et celui d'un bloc standard. Enfin, nous avons comparé le compte de résultat avec le personnel para-médical observé et celui qui nous semblait nécessaire. Résultats : L'UPOG a pris en charge 253 patients en un an dont 215 (84 %) ont bénéficié d'une intervention chirurgicale. Le compte de résultat était positif que ce soit pour un bloc d'urgence (+ 741 kEuros) ou un bloc standard (+ 490 kEuros) et restait positif lorsque le personnel paramédical était incrémenté (respectivement + 629 et + 156 kEuros). Conclusion : L'UPOG présente un compte de résultat positif quel que soit le modèle utilisé, bloc d'urgence ouvert 24h/24 ou bloc standard et même lorsque le personnel paramédical est incrémenté

Surveillance of noninvasive group A Streptococcus infections in French ambulatory pediatrics before and during the COVID-19 pandemic: a prospective multicenter study from 2018-2022

ABSTRACT: Objectives: We evaluated the burden of noninvasive group A Streptococcus (GAS) infections in ambulatory pediatrics before and during the COVID-19 pandemic in France. Methods: We analyzed data from a national network of ambulatory pediatricians between 2018 and 2022. Clinicians evaluating children ≤15 years old for tonsillopharyngitis, perianal infections, paronychia/blistering dactylitis, and scarlet fever were invited to perform a rapid antigen detection test (RADT) for GAS. Monthly incidence of noninvasive GAS infections per 10,000 visits was modeled using time series analysis, considering two breakpoints: March 2020 (first national lockdown) and March 2022 (end of mandatory mask-wearing in schools). Results: Over the study period, 125 pediatricians recorded 271,084 infectious episodes. GAS-related illnesses represented 4.3% of all infections. In March 2020, the incidence of GAS diseases decreased by 84.5% (P <0.001), with no significant trend until March 2022. After March 2022, the incidence significantly increased (+23.8% per month, P <0.001), with similar patterns across all monitored GAS-related diseases. Conclusion: By using routine clinical data and RADTs, we have monitored changes in the incidence of noninvasive GAS infections in ambulatory pediatrics. COVID-19 mitigation measures have had a major impact on the epidemiology of noninvasive GAS infections, but their relaxation was followed by a surge above baseline levels

A large-scale outbreak of hand, foot and mouth disease, France, as at 28 September 2021

International audienceWe report a large-scale outbreak of hand, foot and mouth disease (HFMD) in France. As at 28 September 2021, 3,403 cases have been reported (47% higher than in 2018–19). We prospectively analysed 210 clinical samples; 190 (90.5%) were enterovirus-positive. Most children presented with atypical HFMD. Coxsackievirus (CV)A6 (49.5%; 94/190) was predominant; no enterovirus A71 was detected. Dermatological and neurological complications of HFMD justify prospective syndromic and virological surveillance for early detection of HFMD outbreaks and identification of associated types

A big-data approach to producing descriptive anthropometric references: a feasibility and validation study of paediatric growth charts

International audienceBackground: Both national and WHO growth charts have been found to be poorly calibrated with the physical growth of children in many countries. We aimed to generate new national growth charts for French children in the context of huge datasets of physical growth measurements routinely collected by office-based health practitioners.Methods: We recruited 32 randomly sampled primary care paediatricians and ten volunteer general practitioners from across the French metropolitan territory who used the same electronic medical records software, from which we extracted all physical growth data for the paediatric patients, with anonymisation. We included measurements from all children born from Jan 1, 1990, and aged 1 month to 18 years by Feb 8, 2018, with birthweight greater than 2500 g, to which an automated process of data cleaning developed to detect and delete measurement or transcription errors was applied. Growth charts for weight and height were derived by using generalised additive models for location, scale, and shape with the Box-Cox power exponential distribution. We compared the new charts to WHO growth charts and existing French national growth charts, and validated our charts using growth data from recent national cross-sectional surveys.Findings: After data cleaning, we included 1 458 468 height and 1 690 340 weight measurements from 238 102 children. When compared with the existing French national and WHO growth charts, all height SD and weight percentile curves for the new growth charts were distinctly above those for the existing French national growth charts, as early as age 1 month, with an average difference of -0·75 SD for height and -0·50 SD for weight for both sexes. Comparison with national cross-sectional surveys showed satisfactory calibration, with generally good fit for children aged 5-6 years and 10-11 years in height and weight and small differences at age 14-15 years.Interpretation: We successfully produced calibrated paediatric growth charts by using a novel big-data approach applied to data routinely collected in clinical practice that could be used in many fields other than anthropometry