Characteristics of Staphylococcus aureus infections to consider in designing an effective vaccine.

_Staphylococcus aureus_ is a very versatile and adaptable microorganism. It can potentially infect virtually any host tissue. Given the appropriate conditions it can become a life-threatening pathogen, or a commensal colonizer of the nose. Extensive antibiotic use for infection control facilitated the rise of antibiotic resistance, stressing the need for alternate forms of control. Vaccine efforts in other pathogens have proved successful, but so far _S. aureus_ candidate vaccines have not been as effective. Here we review _S. aureus_ factors involved in pathogenesis that could help develop a successful vaccine, like host nasal colonization and immune evasion factors. An effective multicomponent vaccine could incorporate antigenic fragments from several _S. aureus_ proteins, preferably involved in colonization, immune evasion and/or toxicity

The Promise of Faculty Inquiry for Teaching and Learning Basic Skills

Shares insights from the Strengthening Pre-collegiate Education in Community Colleges project on how teachers' systematic and collaborative analyses of new approaches and practices foster innovation and improvement in basic English and math instruction

Basic Skills for Complex Lives: Designs for Learning in the Community College

Outlines the Strengthening Pre-collegiate Education in Community Colleges project's activities, results, and lessons learned, including five principles for teaching underprepared students. Recommends an institution-wide focus and faculty collaboration

Comentarios bibliográficos

Reseña de los siguientes libros: - Geosynclines, por Jean Aubouin, 335 p., 67 fig., 2 tabl. Elsevier, Amsterdam, New York. 1965. - Geología, por Bermudo Meléndez y José María Fuster, 687 p figs.,cuad. Paraninfo. Madrid, 1966. Con prólogo de Francisco Hernández Pacheco

Cno Abundances Of Hydrogen-Deficient Carbon And R Coronae Borealis Stars: A View Of The Nucleosynthesis In A White Dwarf Merger

We present high-resolution (R similar to 50,000) observations of near-IR transitions of CO and CN of the five known hydrogen-deficient carbon (HdC) stars and four R Coronae Borealis (RCB) stars. We perform an abundance analysis of these stars by using spectrum synthesis and state-of-the-art MARCS model atmospheres for cool hydrogen-deficient stars. Our analysis confirms reports by Clayton and colleagues that those HdC stars exhibiting CO lines in their spectrum and the cool RCB star SAps are strongly enriched in (18)O(with (16)O/(18)Oratios ranging from 0.3 to 16). Nitrogen and carbon are in the form of (14)N and (12)C, respectively. Elemental abundances for CNO are obtained from C I, Ci2, CN, and CO lines. Difficulties in deriving the carbon abundance are discussed. Abundances of Na from Na I lines and S from S I lines are obtained. Elemental and isotopic CNO abundances suggest that HdC and RCB stars may be related objects, and that they probably formed from a merger of an He white dwarf with a C-O white dwarf.Robert A. Welch Foundation of Houston, TexasSwedish Research CouncilGS-2006A-C-13GS-2007A-DD-1McDonald Observator

Los mojones fundacionales del la ciudad de La Plata

Con el discurso del Dr. Dardo Rocha pronunciado en la Asamblea Legislativa con motivo de asumir el cargo de gobernador de la provincia el 1 de mayo de 1881 y la aprobaci&oacute;n de la Ley de fundaci&oacute;n en el partido de Ensenada de la futura capital bonaerense, el 27 de abril de 1882, comienza a tratarse el deslinde, divisi&oacute;n y amojonamiento de la ciudad de La Plata. (Art. 3 de la citada ley). El decreto provincial del 7 de mayo de 1881 encomienda al Departamento de Ingenieros la traza para la nueva capital siendo designados, con fecha 3 de junio del mismo a&ntilde;o, todos sus miembros. El Presidente es el Ing. Francisco Lavalle y en la secci&oacute;n de trabajos catastrales son nombrados el Sr. Germ&aacute;n Khur, Rafael Hern&aacute;ndez, Juan Ferrari y Francisco Silveyra. Estas designaciones son modificadas a mediados de noviembre del siguiente a&ntilde;o donde figura como Presidente el Ing. Jorge Coquet. (P&aacute;rrafo extra&iacute;do a modo de resumen)</em

Urban Water Conservation and Efficiency Potential in California

Improving urban water-use efficiency is a key solution to California's short-term and longterm water challenges: from drought to unsustainable groundwater use to growing tensions over limited supplies. Reducing unnecessary water withdrawals leaves more water in reservoirs and aquifers for future use and has tangible benefits to fish and other wildlife in our rivers and estuaries. In addition, improving water-use efficiency and reducing waste can save energy, lower water and wastewater treatment costs, and eliminate the need for costly new infrastructure

Listening to Students About Learning

Shares findings from the Strengthening Pre-Collegiate Education in Community Colleges project about how teachers can help students become more engaged and likely to succeed by better observing student learning and introducing innovative instruction

SPITZER observations of the λ Orionis cluster. II. Disks around solar-type and low-mass stars

We present IRAC/MIPS Spitzer Space Telescope observations of the solar-type and the low-mass stellar population of the young (~5Myr) λ Orionis cluster. Combining optical and Two Micron All Sky Survey photometry, we identify 436 stars as probable members of the cluster. Given the distance (450 pc) and the age of the cluster, our sample ranges in mass from 2 M_⊙ to objects below the substellar limit. With the addition of the Spitzer mid-infrared data, we have identified 49 stars bearing disks in the stellar cluster. Using spectral energy distribution slopes, we place objects in several classes: non-excess stars (diskless), stars with optically thick disks, stars with “evolved disks” (with smaller excesses than optically thick disk systems), and “transitional disk” candidates (in which the inner disk is partially or fully cleared). The disk fraction depends on the stellar mass, ranging from ~6% for K-type stars (R_C − J 4). We confirm the dependence of disk fraction on stellar mass in this age range found in other studies. Regarding clustering levels, the overall fraction of disks in the λ Orionis cluster is similar to those reported in other stellar groups with ages normally quoted as ~5Myr