7,646 research outputs found

    Comércio eletrônico

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    O presente estudo tem como objetivo identificar as vantagens e desafios referentes ao comércio eletrônico. A pesquisa se dá em caráter exploratório com abordagem qualitativa. O trabalho apresenta diversas teorias sobre as características do comércio eletrônico. Tendo em vista o atual cenário, é de extrema importância as empresas estarem atentas as vantagens e desafios que o comércio eletrônico abrange, pois esta prática tende a ser o futuro das operações comerciais. Assim o embasamento teórico visa revisar as diversas teorias que abrangem o tema comércio eletrônico. Os resultados da pesquisa revelam a necessidade de um alto grau de comprometimento das empresas para implementar esse novo conceito, tendo que se reestruturar para absorver as vantagens referentes ao comércio eletrônico

    CLIMATIC CHARACTERISTICS AND THEIR IMPLICATIONS AMONG THE PEDOLOGICAL AND TOPOGRAPHICAL ASPECTS OF SOUTHERN BAHIA, BRAZIL

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    In this paper, the climatic characteristics, and their advantages in the pedological andtopographical aspects of the mesoregion of southern Bahia, Brazil, were evaluated. The study was developed in the territory of the Discovery Coast and Far South, located in the southern mesoregion of the state of Bahia. Temperature and precipitation data were obtained on the WordClim plataform and interpolated using ordinary kriging, these climate data were used to calculate evapotranspiration and soil water deficit. The soils were derived from the pedological mapping of Bahia, on a scale of 1:1250000; hypsometry and slope were obtained using the Digital Elevation Model. The climatic variables with the physical attributes of the region were tested by Pearson correlation and simple linear regression. The annual precipitation is distributed between 878.8 mm /year and maximums of 1,619 mm/year, while the average annual temperature is between 22.01 °C and 26.08 °C. The greatest potential annual evapotranspiration occurs in December and January, in the areas that have thehighest rainfall and average annual temperatures. The annual water deficit of water showed values of 88.8 to 178 mm observed in the south and northwest of the area. The area has a predominant elevation of up to 320 m and the relief is predominantly flat to wavy. The relationship between climatic, pedological and topographic data indicated that, spatially, low and flat areas with a predominance of latosols are associated with higher precipitation and higher temperature between April and September. The pedology in relation to water deficit, temperature and evapotranspiration did not present significant correlation, which indicates that the territorial extensions of the soil types do not directly interact with the local climatic conditions. The analysis contributesto the understanding of climatic factors and their relationshipsto the other physical characteristics of the south of the Bahia.

    Ventilation Method during Intensive Care Unit Transport after Cardiac Surgeries; When Should We Use A Ventilator?

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    Background Problem Statement: Manual ventilation with AMBU bag is utilized mostly for transporting post cardiac surgery patients to the intensive care unit, but some patients need mechanical ventilation due to concern for oxygenation, ventilation, and cardiac function. Also, transport can be a critical moment because of limited hemodynamic information and suboptimal environment for therapeutic intervention. Thus, risk stratification for appropriate ventilation is necessary for safe transport. • Project AIM: We assessed biventricular function (with a hand-held echocardiography), arterial blood gas, and hemodynamics pre and post transport in manual and mechanical ventilation groups

    Professionalism and moral injury in a capitalist healthcare system

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    Professionalism cautions against profit while capitalism exists for profit. This case is a structural analysis of capitalism in a clinical setting that reveals physicians to be simultaneously wage laborers and professionals. Capitalism generates profit. Professionalism views profit as a conflict of interest that erodes trust in the doctor-patient relationship. Managing these conflicting values causes moral injury for physicians, which is a driver of physician burnout

    Effect of age and sex on echocardiographic left ventricular diastolic function parameters in patients with preserved ejection fraction and normal valvular function

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    Background: We conducted a retrospective study to specify the effect of age and gender on echocardiographic left ventricular diastolic function parameters.Methods: We included echocardiograms done in our institution between 1995 and 2007, for which data on diastolic function were available. In order to target a population as close aspossible to healthy subjects, echocardiograms reporting abnormal contraction, valvulopathy or extreme data were excluded.Results: A total of 14,298 patients (mean age 58.53 years; men 49.1%) were included in the study. Sex did not influence E/A ratio (p = 0.298) but age decreased it significantly (p < 0.001). E/e ratio increased significantly with age (p < 0.001) and was higher in women than in men (p < 0.001). After the age of 40, more than 10% of the patients had an E/e ratio superior than 8.Conclusions: To our knowledge, this is the most imposing study — in terms of number of patients from first to tenth decade of life that were included — addressing the effect of age and gender on diastolic function. Our results stress the need for future prospective trials to establishnormal diastolic function parameters according to age and gender, notably for the E/e ratio for which a significant proportion of our population had a ratio superior of what is actually considered normal

    Dextromethorphan-quinidine is helpful for pseudobulbar affect disorder in stroke patients

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    An informed consent article using Hammond FM, Alexander DN, Cutler AJ, et al. PRISM II: an open-label study to assess effectiveness of dextromethorphan/quinidine for pseudobulbar affect in patients with dementia, stroke or traumatic brain injury. BMC Neurology. 2016;16:89. https://doi.org/10.1186/s12883-016-0609-0 for a patient with pseudobulbar affect following strok

    Requirement of JNK1 for endothelial cell injury in atherogenesis

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    AbstractObjectiveThe c-Jun N-terminal kinase (JNK) family regulates fundamental physiological processes including apoptosis and metabolism. Although JNK2 is known to promote foam cell formation during atherosclerosis, the potential role of JNK1 is uncertain. We examined the potential influence of JNK1 and its negative regulator, MAP kinase phosphatase-1 (MKP-1), on endothelial cell (EC) injury and early lesion formation using hypercholesterolemic LDLR−/− mice.Methods and resultsTo assess the function of JNK1 in early atherogenesis, we measured EC apoptosis and lesion formation in LDLR−/− or LDLR−/−/JNK1−/− mice exposed to a high fat diet for 6 weeks. En face staining using antibodies that recognise active, cleaved caspase-3 (apoptosis) or using Sudan IV (lipid deposition) revealed that genetic deletion of JNK1 reduced EC apoptosis and lesion formation in hypercholesterolemic mice. By contrast, although EC apoptosis was enhanced in LDLR−/−/MKP-1−/− mice compared to LDLR−/− mice, lesion formation was unaltered.ConclusionWe conclude that JNK1 is required for EC apoptosis and lipid deposition during early atherogenesis. Thus pharmacological inhibitors of JNK may reduce atherosclerosis by preventing EC injury as well as by influencing foam cell formation

    Why Some Interfaces Cannot be Sharp

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    A central goal of modern materials physics and nanoscience is control of materials and their interfaces to atomic dimensions. For interfaces between polar and non-polar layers, this goal is thwarted by a polar catastrophe that forces an interfacial reconstruction. In traditional semiconductors this reconstruction is achieved by an atomic disordering and stoichiometry change at the interface, but in multivalent oxides a new option is available: if the electrons can move, the atoms don`t have to. Using atomic-scale electron energy loss spectroscopy we find that there is a fundamental asymmetry between ionically and electronically compensated interfaces, both in interfacial sharpness and carrier density. This suggests a general strategy to design sharp interfaces, remove interfacial screening charges, control the band offset, and hence dramatically improving the performance of oxide devices.Comment: 12 pages of text, 6 figure
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