33 research outputs found

    The Dynamics of Relational Quality in Co-Development Alliances

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    The Impact of Software as a Service on IS Authority – A Contingency Perspective

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    For some business applications, using Software as a Service (SaaS) is becoming increasingly popular. However, it is largely unknown how SaaS adoption affects the arrangements between business and IT departments. In this study, we take a contingency approach to investigate how firms allocate authority for SaaS applications. Based on semi-structured interviews with business and IT representatives of companies that have adopted the wide-spread SaaS solution Salesforce CRM, we extend existing contingency theory to propose a set of factors for governance arrangements on the application level. These factors are used in a comparative case study of 4 cases of SaaS adoption to explain why application authority is allocated either to the business or the IT side. The results suggest that in most cases there exist dominant and reinforcing contingencies determining a definite mode of SaaS governance

    Multicentre, interventional, single-arm study protocol of telemonitored circadian rhythms and patient-reported outcomes for improving mFOLFIRINOX safety in patients with pancreatic cancer (MultiDom, NCT04263948)

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    Introduction: Circadian clocks regulate cellular proliferation and drug effects. Tolerability and/or efficacy of anticancer therapies have been improved by their administration according to circadian rhythms, while being predicted by circadian robustness. The combination of leucovorin, fluorouracil, irinotecan and oxaliplatin (mFOLFIRINOX) is a standard treatment for pancreatic ductal adenocarcinoma (PDAC), that generates grades 3–4 adverse events in the majority of patients and an estimated 15%–30% emergency admission rate. The MultiDom study evaluates whether mFOLFIRINOX safety can be improved using a novel circadian-based telemonitoring-telecare platform in patients at home. The detection of early warning signals of clinical toxicities could guide their early management, possibly preventing emergency hospital admissions. Methods and analysis: This multicentre, interventional, prospective, longitudinal, single-arm study hypothesises that the mFOLFIRINOX-related emergency admission rate will be 5% (95% CI 1.7% to 13.7%), among 67 patients with advanced PDAC. Study participation is 7 weeks for each patient, including a reference week before chemotherapy onset and 6 weeks afterwards. Accelerometry and body temperature are measured q1-min using a continuously worn telecommunicating chest surface sensor, daily body weight is self-measured with a telecommunicating balance and 23 electronic patient-reported outcomes (e-PROs) are self-rated using a tablet. Hidden Markov model, spectral analyses and other algorithms automatically compute physical activity, sleep, temperature, body weight change, e-PRO severity and 12 circadian sleep/activity parameters, including the dichotomy index I<O (% activity ‘in-bed’ below median activity ‘out-of-bed’), once to four times daily. Health professionals access visual displays of near-real time parameter dynamics and receive automatic alerts, with trackable digital follow-up. Ethics and dissemination: The study has been approved by the National Agency for Medication and Health Product Safety (ANSM) and Ethics Committee West V (2 July 2019; third amendment, 14 June 2022). The data will be disseminated at conferences and in peer-reviewed journals and will support large-scale randomised evaluation. Trial registration numbers: NCT04263948 and ID RCB-2019-A00566-51

    Rentes minières et transferts internationaux

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    Bidault Francis. Rentes minières et transferts internationaux. In: Cahiers d'économie politique, n°5, 1979. Théorie de la rente. Prix de production internationnaux. Conception classique de la concurrence. Débat sur la théorie de la valeur., sous la direction de Patrick Maurisson. pp. 75-84

    L'insertion des P.M.I. dans la nouvelle division internationale du travail

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    Aitelhadj Smail, Bidault Francis. L'insertion des P.M.I. dans la nouvelle division internationale du travail. In: Revue d'économie industrielle, vol. 14, 4e trimestre 1980. Vers une nouvelle division internationale du travail. pp. 94-102

    The dynamics of relational quality in co-development alliances

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