Studies on the Helminth Fauna of Alaska. XLII. \u3ci\u3eAploparaksis turdi\u3c/i\u3e sp. n., a Hymenolepidid Cestode from Thrushes

Aploparaksis turdi sp. n. (Cestoda: Hymenolepididae) is described from the robin, Turdus migratorius L., and recorded also from the varied thrush, Ixoreus naevius (Gmelin), from Iliamna Lake, upper Alaska Peninsula. This cestode is distinguished from the three previously known species of Aploparaksis s. l. occurring in passeriform birds by the size and number of rostellar hooks and by the arrangement and proportions of the genital organs. It is concluded that the validity of the genus Monorcholepis Oshmarin, 1961, to which certain of these species have been assigned, is questionable, and the latter genus is considered to be a synonym of Aploparaksis Clerc, 1903

Detection of Phosphorus and Nitrogen Deficiencies in Corn Using Spectral Radiance Measurements

Applications of remote sensing in crop production are becoming increasingly popular due in part to an increased concern with pollution of surface and ground waters due to over-fertilization of agricultural lands and the need to compensate for spatial variability in a field. Past research in this area has focused primarily on N stress in crops. Other stresses and the interactions have not been fully evaluated. A field experiment was conducted to determine wavelengths and/or combinations of wavelengths that are indicative of P and N deficiency and also the interaction between these in corn (Zea mays L.). The field experiment was a randomized complete block design with four replications using a factorial arrangement of treatments in an irrigated continuous corn system. The treatment included four N rates (0, 67, 134, and 269 kg N ha-1) and four P rates (0, 22, 45, and 67 kg P ha-1). Spectral radiance measurements were taken at various growth stages in increments from 350 to 1000 nm and correlated with plant N and P concentration, plant biomass, grain N and P concentration, and grain yield. Reflectance in the near-infrared (NIR) and blue regions was found to predict early season P stress between growth stages V6 and V8. Late season detection of P stress was not achieved. Plant N concentration was best predicted using reflectance in the red and green regions of the spectrum, while grain yield was estimated using reflectance in the NIR region, with the particular wavelengths of importance changing with growth stage

Improving adherence to acute low back pain guideline recommendations with chiropractors and physiotherapists: the ALIGN cluster randomised controlled trial

Background Acute low back pain is a common condition, has high burden, and there are evidence-to-practice gaps in the chiropractic and physiotherapy setting for imaging and giving advice to stay active. The aim of this cluster randomised trial was to estimate the effects of a theory- and evidence-based implementation intervention to increase chiropractors’ and physiotherapists’ adherence to a guideline for acute low back pain compared with the comparator (passive dissemination of the guideline). In particular, the primary aim of the intervention was to reduce inappropriate imaging referral and improve patient low back pain outcomes, and to determine whether this intervention was cost-effective. Methods Physiotherapy and chiropractic practices in the state of Victoria, Australia, comprising at least one practising clinician who provided care to patients with acute low back pain, were invited to participate. Patients attending these practices were included if they had acute non-specific low back pain (duration less than 3 months), were 18 years of age or older, and were able to understand and read English. Practices were randomly assigned either to a tailored, multi-faceted intervention based on the guideline (interactive educational symposium plus academic detailing) or passive dissemination of the guideline (comparator). A statistician independent of the study team undertook stratified randomisation using computer-generated random numbers; four strata were defined by professional group and the rural or metropolitan location of the practice. Investigators not involved in intervention delivery were blinded to allocation. Primary outcomes were X-ray referral self-reported by clinicians using a checklist and patient low back pain-specific disability (at 3 months). Results A total of 104 practices (43 chiropractors, 85 physiotherapists; 755 patients) were assigned to the intervention and 106 practices (45 chiropractors, 97 physiotherapists; 603 patients) to the comparator; 449 patients were available for the patient-level primary outcome. There was no important difference in the odds of patients being referred for X-ray (adjusted (Adj) OR: 1.40; 95% CI 0.51, 3.87; Adj risk difference (RD): 0.01; 95% CI − 0.02, 0.04) or patient low back pain-specific disability (Adj mean difference: 0.37; 95% CI − 0.48, 1.21, scale 0–24). The intervention did lead to improvement for some key secondary outcomes, including giving advice to stay active (Adj OR: 1.96; 95% CI 1.20, 3.22; Adj RD: 0.10; 95% CI 0.01, 0.19) and intending to adhere to the guideline recommendations (e.g. intention to refer for X-ray: Adj OR: 0.27; 95% CI 0.17, 0.44; intention to give advice to stay active: Adj OR: 2.37; 95% CI 1.51, 3.74). Conclusions Intervention group clinicians were more likely to give advice to stay active and to intend to adhere to the guideline recommendations about X-ray referral. The intervention did not change the primary study outcomes, with no important differences in X-ray referral and patient disability between groups, implying that hypothesised reductions in health service utilisation and/or productivity gains are unlikely to offset the direct costs of the intervention. We report these results with the caveat that we enrolled less patients into the trial than our determined sample size. We cannot recommend this intervention as a cost-effective use of resources

Lensing at cosmological scales: a test of higher dimensional gravity

Recent developments in gravitational lensing astronomy have paved the way to genuine mappings of the gravitational potential at cosmological scales. We stress that comparing these data with traditional large scale structure surveys will provide us with a test of gravity at such scales. These constraints could be of great importance in the framework of higher dimensional cosmological models.Comment: 4 pages, latex, 3 figure

Toward an internally consistent astronomical distance scale

Accurate astronomical distance determination is crucial for all fields in astrophysics, from Galactic to cosmological scales. Despite, or perhaps because of, significant efforts to determine accurate distances, using a wide range of methods, tracers, and techniques, an internally consistent astronomical distance framework has not yet been established. We review current efforts to homogenize the Local Group's distance framework, with particular emphasis on the potential of RR Lyrae stars as distance indicators, and attempt to extend this in an internally consistent manner to cosmological distances. Calibration based on Type Ia supernovae and distance determinations based on gravitational lensing represent particularly promising approaches. We provide a positive outlook to improvements to the status quo expected from future surveys, missions, and facilities. Astronomical distance determination has clearly reached maturity and near-consistency.Comment: Review article, 59 pages (4 figures); Space Science Reviews, in press (chapter 8 of a special collection resulting from the May 2016 ISSI-BJ workshop on Astronomical Distance Determination in the Space Age

N-Acetylcysteine (NAC) in Schizophrenia Resistant to Clozapine: A Double-Blind, Randomized, Placebo-Controlled Trial Targeting Negative Symptoms

Background and hypothesis Clozapine is the most effective antipsychotic for treatment-resistant schizophrenia, yet a significant proportion of individuals on clozapine continue to experience disabling symptoms, despite being treated with an adequate dose. There is a need for adjunct treatments to augment clozapine, notably for negative and cognitive symptoms. One such potential agent is the glutathione precursor N-acetylcysteine (NAC). Study design A randomized double-blind, multi-center, placebo-controlled trial for clozapine patients with enduring psychotic symptoms (n = 84) was undertaken to investigate the efficacy of adjunctive NAC (2 g daily) for negative symptoms, cognition and quality of life (QoL). Efficacy was assessed at 8, 24, and 52 weeks. Study results NAC did not significantly improve negative symptoms (P = .62), overall cognition (P = .71) or quality of life (Manchester quality of life: P = .11; Assessment of quality of life: P = .57) at any time point over a 1-year period of treatment. There were no differences in reported side effects between the groups (P = .26). Conclusions NAC did not significantly improve schizophrenia symptoms, cognition, or quality of life in treatment-resistant patients taking clozapine. This trial was registered with "Australian and New Zealand Clinical Trials" on the 30 May, 2016 (Registration Number: ACTRN12615001273572).Erica Neill, Susan L. Rossell, Caitlin Yolland, Denny Meyer, Cherrie Galletly, Anthony Harris, Dan Siskind, Michael Berk, Kiymet Bozaoglu, Frances Dark, Olivia M. Dean, Paul S. Francis, Dennis Liu, Andrea Phillipou, Jerome Sarris, and David J. Castl