120 research outputs found

    Encountering the Niobe’s Children: Vernon Lee’s queer formalism and the empathy of sculpture

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    The materiality of sculpture was essential to Vernon Lee’s psychological theory of aesthetics based on the beholder’s physical responses. Through collaboration with her lover Clementina Anstruther-Thomson, Lee developed a theory of embodiment based on German psychological empathy theories which was reliant on gallery rather than laboratory experiments. This chapter focuses on the reception of their work within the psychological circles of the time and, in contrast to interpretation of the two women’s intellectual collaboration as a transposition of lesbian desire, I argue that Lee’s dialogue with Karl Groos around the concept of “inner mimicry” is essential to examine how sculpture also allowed her to explore sexuality plastically. Originating in late-Victorian discourses around formalism, Lee’s aesthetic engagement with the past represents an ethics of embodiment that resonated with modern theories of sexuality

    A severe infective endocarditis successfully treated with linezolid

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    Despite significant improvements in surgical and medical therapy, prosthetic valve endocarditis (PVE) is a diagnostic and therapeutic challenge and is often associated with a severe prognosis. We report a case of a 59-year-old woman, with  PVE and bacterial endocarditis (Streptococcus bovis) successfully treated with linezolid. Linezolid is a bacteriostatic oxazolidinone antibiotic that has been proven to be effective for the treatment of patients with pneumonia, skin and soft tissue infections, and infections due to Gram-positive cocci. Linezolid is not yet recognised as a standard therapy for infective endocarditis, but its use becomes a necessity when infection is due to multidrug-resistant microorganisms

    Microswimmer trapping in surface waves with shear

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    Many species of phytoplankton migrate vertically near the surface of the ocean, either in search of light or nutrients. These motile organisms are affected by ocean waves at the surface. We derive a set of wave-averaged equations to describe the motion of spheroidal microswimmers. We include several possible effects, such as gyrotaxis, settling, and wind-driven shear. In addition to the well-known Stokes drift, the microswimmer orbits depend on their orientation in a way that can lead to trapping at a particular depth; this in turn can affect transport of organisms, and may help explain observed phytoplankton layers in the ocean.Comment: 13 pages, 5 figures, to be published in Proceedings of the Royal Society

    characterization of the geographical and varietal origin of wheat and bread by means of nuclear magnetic resonance nmr isotope ratio mass spectrometry irms methods and chemometrics a review

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    In recent years, food authentication, in terms of geographical and varietal/animal origins, is considered of primary importance at all levels of the production process. Therefore, it is clear that there is an economic basis to develop analytical methods able to certify the declared origin of food products, in order to protect consumers and honest producers from fraud and unfair competition, respectively; consequently, during recent years, several food authentication techniques have been proposed. This review attempted to present in a critical way the contribution of High Resolution Nuclear Magnetic Resonance (HR-NMR) and Isotope Ratio Mass Spectrometry (IRMS) techniques in the assessment of quality and authenticity, mainly in terms of characterization of geographical and varietal origin, of wheat and wheat products, focusing on the most important studies to this direction

    The biomedical piglet: establishing reference intervals for haematology and clinical chemistry parameters of two age groups with and without iron supplementation

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    Background: The similarities between swine and humans in physiological and genomic patterns, and the great correlation in size and anatomy, make pigs extremely useful in preclinical studies. New-born piglets can represent a model for congenital and genetic diseases in new-born children. It is known that piglets may have significant differences in clinicopathological results compared to adult pigs. Therefore, adult laboratory reference intervals cannot be applied to piglets. The aim of this study was to compare haematological and chemical variables in piglets of two ages and determinate age-related reference intervals for commercial hybrid young pigs. Blood samples were collected under general anaesthesia from 130 animals divided into five- (P5) and 30- (P30) day-old piglets. Only P30 animals were treated with parenteral iron after birth. Samples were analysed using automated haematology (ADVIA 2120) and chemistry analysers, and age-related reference intervals were calculated. Results: Significant higher values of RBC, Hb and HCT were observed in P30 animals when compared to P5, with an opposite trend for MCV. These results were associated with a reduction of the RBC regeneration process and the thrombopoietic response. The TSAT and TIBC were significantly higher in P30 compared to P5; however, piglets remained iron deficient compared to adult reference intervals reported previously. Conclusions: In conclusion, this paper emphasises the high variability occurring in clinicopathological variables between new-born and 30-day-old pigs, and between piglets and adult pigs. This study provides valuable reference data for piglets at precise ages and could be used in the future as historical control improving the Reduction in animal experiments, as suggested by the 3Rs principle
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