Convex and non-convex regularization methods for spatial point processes intensity estimation

This paper deals with feature selection procedures for spatial point processes intensity estimation. We consider regularized versions of estimating equations based on Campbell theorem derived from two classical functions: Poisson likelihood and logistic regression likelihood. We provide general conditions on the spatial point processes and on penalty functions which ensure consistency, sparsity and asymptotic normality. We discuss the numerical implementation and assess finite sample properties in a simulation study. Finally, an application to tropical forestry datasets illustrates the use of the proposed methods

Annular cracks in thin films of nanoparticle suspensions drying on a fiber

We report an experimental study of the crack pattern formed during the drying of a colloidal suspension. A horizontal fiber, which provides a one dimensional, boundary-free substrate, is coated by a film of micronic thickness. The geometry imposes a remarkable annular crack pattern and allowing precise measurements of the crack spacing over a short range of film thickness (between 2 and 10 $\mu$m) which varies linearly with the film height. We compare our experimental data with a model proposed by Kitsunezaki which suggests that the variation of the crack spacing with the film thickness depends on the ratio between a critical stress at cracking and a critical stress for slipping on the substrate. By measuring the friction force of the colloidal gels on a hydrophobic surface through a cantilever technique, we can deduce the critical crack stress for these colloidal gels simply by measuring the crack spacing of the pattern.Comment: Accepted in EP

Instability and morphology of polymer solutions coating a fiber

We report an experimental study on the dynamics of a thin film of polymer solution coating a vertical fiber. The liquid film has first a constant thickness and then undergoes the Rayleigh-Plateau instability which leads to the formation of sequences of drops, separated by a thin film, moving down at a constant velocity. Different polymer solutions are used, i.e. xanthan solutions and polyacrylamide (PAAm) solutions. These solutions both exhibit shear-rate dependence of the viscosity, but for PAAm solutions, there are strong normal stresses in addition of the shear-thinning effect. We characterize experimentally and separately the effects of these two non-Newtonian properties on the flow on the fiber. Thus, in the flat film observed before the emergence of the drops, only shear-thinning effect plays a role and tends to thin the film compared to the Newtonian case. The effect of the non-Newtonian rheology on the Rayleigh-Plateau instability is then investigated through the measurements of the growth rate and the wavelength of the instability. Results are in good agreement with linear stability analysis for a shear-thinning fluid. The effect of normal stress can be taken into account by considering an effective surface tension which tends to decrease the growth rate of the instability. Finally, the dependence of the morphology of the drops with the normal stress is investigated and a simplified model including the normal stress within the lubrication approximation provides good quantitative results on the shape of the drops.Comment: Accepted in Journal of Fluid Mechanic

Combining Model-Based Design (MBD) and Model-Based Testing (MBT) for early validation of embedded real-time systems

International audienceThis paper describes an approach combining Model-Based Engineering (MBE) and Model-Based Testing, and its application to requirements validation for an embedded Instrumentation & Control (I&C) system. Many aspects of the embedded system can thus be validated early in the lifecycle, long before an actual implementation is developed, and, most importantly, requirements can be validated before the system is implemented. A flexible integration environment makes it possible to reuse the test cases throughout the lifecycle. This approach is being implemented in the CONNEXION R&D project, using Esterel Technologies’ SCADE Suite and All4tec’s MaTeLo, with Corys’ ALICES as an integration environment

Programmation Haute Performance pour Architectures hybrides

National audienceProposer un modèle de distribution des calculs et des données et générer de façon semi-automatique un code parallèle efficace en consommation mémoire et en temps d'exécution

A diferenciação sociocultural das crianças. Algumas reflexões linguisticas.

Après avoir analysé Ia pensé dichotomique et son fonctionnement, en particulier au niveau de Ia linguistique, en montrant comment to dichotomisation a une signi fication idéologique, l’auteur essaye de préciser comente les travaux de B. Bernstein et de son école s’inscrivent dans ce champ. Selon l’auteur, le línguiste doit dépasser de dichotomie implicitement surnormative (code restrict, code elaboré, etc.) et lutter contre les tabous linguistiques en respectant la différence au lieu de chercher à Ia neutraliser. Il conclut que Ia notion de handícap linguistique constitue une totalisation idéologique que le faits ne justifient pa

The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution

BACKGROUND: Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing radiation in three human tumor cell lines (HCT-116, MiAPaCa-2 and A-549) bearing a point mutation in the K-Ras gene. RESULTS: RPR-130401 inhibited cell growth with an IC(50) of 50 nM (HCT-116), 120 nM (MiAPaCa-2) and 710 nM (A-549), with a poor incidence of apoptosis. The drug brought about G1 and S phase depletion together with arrest of cells in G2 phase and induced a significant accumulation of hyperploid cells showing active S phase DNA synthesis, with HCT-116 and A-549 cells being the most and least responsive, respectively. The drug also produced dramatic changes of the nuclear lamin B pattern, without lamin B cleavage and perturbation of the actin cytoskeleton. On the other hand, RPR-130401 elicited strictly additive interaction in combined treatment with ionizing radiation with regard to cell kill, altered cell cycle progression and induced hyperploidy. CONCLUSIONS: The data suggest that disruption of orderly progression through mitosis and cytokinesis, is a major outcome of drug action and that this effect proceeds from inhibition of lamin B farnesylation. It is anticipated from the strict additivity of RPR-130401 and radiation that neither induced radiation resistance nor acute or late complications of radiotherapy, should occur in combined treatment with RPR-130401