3 research outputs found
Pyoderma gangrenosum of the “sinus mammarum” in ulcerative colitis
The first part of this article deals with the report of a patient suffe -
ring from pyoderma gangrenosum of the “sinus mammarum” associa -
ted with asymptomatic ulcerative colitis. This is followed by a revision
of the present epidemiological, etiological, pathogenetic and clinical
knowledges about this systemic manifestation of chronic phlogosis of the
colon.
The Authors have analysed the treatment for this condition and
emphasized the resistance of the cutaneous ulcer encountered to conven -
tional medical therapy of the underlying colonic disease which proved
to be efficacious only on the latter; this led to integrate traditional
treatment with the use of perilesional injections of small doses of calcic
heparin as an alternative to immunosuppressive drugs or surgery.
Topical antithrombotic treatment, which can be justified by the histo -
logical findings of phenomena of the vasculitis in the edge of pyoderma
gangrenosum, demonstrated to be crucial and represents a peculiarity
in the case here reported, which is unique in the literature as far as the
Authors know, since it has not been experimented by anyone else
Acute acalculous cholecystitis during the course of primary Epstein-Barr virus infection: a new case and a review of the literature
OBJECTIVE:
The aim of this study was to describe a case of acute acalculous cholecystitis occurring in the course of primary Epstein-Barr virus (EBV) infection.
METHODS:
The clinical features of the case were analyzed and compared to those of three other similar cases reported in the international literature.
RESULTS:
All cases occurred in European females with cholestatic hepatitis, presented with gallbladder wall thickening, and recovered uneventfully without the need for surgical intervention.
CONCLUSIONS:
Acute acalculous cholecystitis may occur during the course of acute EBV infection, especially in patients with cholestatic hepatitis. Clinicians should be aware of the possible involvement of the gallbladder during EBV infection to avoid unnecessary invasive procedures or the overuse of antibiotics