Single Electron Transistors

Contains description of one research project and a list of publications.Joint Services Electronics Program Contract DAAL03-92-C-0001National Science Foundation Grant ECS 88-13250National Science Foundation Grant ECS 92-0342

Single Electron Transistors

Contains description of one research project.Joint Services Electronics Program Contract DAAL03-89-C-0001Joint Services Electronics Program Contract DAAL03-92-C-0001National Science Foundation Grant ECS 88-1325

New Look at Naltrexone Hydrochloride Hydrates: Understanding Phase Behavior and Characterization of Two Dihydrate Polymorphs

The phase behavior and characterization of two forms of naltrexone hydrochloride dihydrate are presented. A metastable form was isolated first in the solid state under kinetically controlled conditions, namely dehydration of a higher hydrate followed by exposure to ∼38% relative humidity. The second, more thermodynamically stable polymorph was isolated from an aqueous slurry at an elevated temperature. The phase transition boundaries between naltrexone hydrochloride anhydrate and the metastable hydrate species are established through a combination of slurry and moisture sorption experiments to provide a detailed mechanistic understanding of the hydration/dehydration behavior