368 research outputs found

    Influences on the triple alpha process beyond the Hoyle state

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    7 pags., 3 figs. -- International Symposium on Nuclear Astrophysics - Nuclei in the Cosmos - IX, 25-30 June 2006, CERNThe triple alpha process is studied using indirect methods. The beta decays of 12N and 12B are used to probe the triple alpha continuum of 12C. Different independent breakup channels are identified, consistently showing that the 10 MeV strength is dominated by a 0+ state interfering with the Hoyle state ghost. The 13–14 MeV region on the other hand is dominated by a 2 + state

    Opposing Effects of Prior Infection versus Prior Vaccination on Vaccine Immunogenicity against Influenza A(H3N2) Viruses

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    Prior vaccination can alternately enhance or attenuate influenza vaccine immunogenicity and effectiveness. Analogously, we found that vaccine immunogenicity was enhanced by prior A(H3N2) virus infection among participants of the Ha Nam Cohort, Viet Nam, but was attenuated by prior vaccination among Australian Health Care Workers (HCWs) vaccinated in the same year. Here, we combined these studies to directly compare antibody titers against 35 A(H3N2) viruses spanning 1968–2018. Participants received licensed inactivated vaccines containing A/HongKong/4801/2014 (H3N2). The analysis was limited to participants aged 18–65 Y, and compared those exposed to A(H3N2) viruses circulating since 2009 by infection (Ha Nam) or vaccination (HCWs) to a reference group who had no recent A(H3N2) infection or vaccination (Ha Nam). Antibody responses were compared by fitting titer/titer-rise landscapes across strains, and by estimating titer ratios to the reference group of 2009–2018 viruses. Pre-vaccination, titers were lowest against 2009–2014 viruses among the reference (no recent exposure) group. Post-vaccination, titers were, on average, two-fold higher among participants with prior infection and two-fold lower among participants with 3–5 prior vaccinations compared to the reference group. Titer rise was negligible among participants with 3–5 prior vaccinations, poor among participants with 1–2 prior vaccinations, and equivalent or better among those with prior infection compared to the reference group. The enhancing effect of prior infection versus the incrementally attenuating effect of prior vaccinations suggests that these exposures may alternately promote and constrain the generation of memory that can be recalled by a new vaccine strain.Annette Fox, Louise Carolan, Vivian Leung, Hoang Vu Mai Phuong, Arseniy Khvorov, Maria Auladell, Yeu-Yang Tseng, Pham Quang Thai, Ian Barr, Kanta Subbarao, Le Thi Quynh Mai, H. Rogier van Doorn, and Sheena G. Sulliva

    Information Needs of Hong Kong Chinese Patients Undergoing Surgery

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    BACKGROUND: The provision of information to patients is an important aspect of contemporary health care. Limitations in health resources necessitates that the provision of information is carefully planned and culturally specific to maximize the benefits to patients from the resources available. AIM AND OBJECTIVES: The purposes of the study were to recognize Chinese surgical patients' information needs on admission and ascertain why the information is important to assist in understanding how it is used and, therefore, its potential impact. METHODS: A descriptive study design was used. A convenience sample of 83 surgical patients took part comprising 51 men and 32 women. An eight-item questionnaire based on the right of patients to information as listed in the Patients' Charter in Hong Kong using a 5-point Likert scale and one open-ended question to comment on why the information was important to them was completed by patients on the day of admission. RESULTS: Patients rated highly the need for all types of information. They rated most highly the need for information about the signs and symptoms indicating postoperative complications and when to seek medical help. Patients did not rate as highly, information regarding why the doctor believes the surgery is important, treatment alternatives and explanation of the procedure. CONCLUSIONS: These findings indicate that Chinese patients are desirous of a range of relevant information. RELEVANCE TO PRACTICE: Nursing staff, in particular, need to consider the 'timeliness' of information and the cultural appropriateness of how information is delivered

    Ecological indicators to capture the effects of fishing on biodiversityand conservation status of marine ecosystems

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    IndiSeas (“Indicators for the Seas”) is a collaborative international working group that was established in2005 to evaluate the status of exploited marine ecosystems using a suite of indicators in a comparative framework. An initial shortlist of seven ecological indicators was selected to quantify the effects of fishing on the broader ecosystem using several criteria (i.e., ecological meaning, sensitivity to fishing, data avail-ability, management objectives and public awareness). The suite comprised: (i) the inverse coefficient of variation of total biomass of surveyed species, (ii) mean fish length in the surveyed community, (iii)mean maximum life span of surveyed fish species, (iv) proportion of predatory fish in the surveyed community, (v) proportion of under and moderately exploited stocks, (vi) total biomass of surveyed species,and (vii) mean trophic level of the landed catch. In line with the Nagoya Strategic Plan of the Convention on Biological Diversity (2011–2020), we extended this suite to emphasize the broader biodiversity and conservation risks in exploited marine ecosystems. We selected a subset of indicators from a list of empirically based candidate biodiversity indicators initially established based on ecological significance to complement the original IndiSeas indicators. The additional selected indicators were: (viii) mean intrinsic vulnerability index of the fish landed catch, (ix) proportion of non-declining exploited species in the surveyed community, (x) catch-based marine trophic index, and (xi) mean trophic level of the surveyed community. Despite the lack of data in some ecosystems, we also selected (xii) mean trophic level of the modelled community, and (xiii) proportion of discards in the fishery as extra indicators. These additional indicators were examined, along with the initial set of IndiSeas ecological indicators, to evaluate whether adding new biodiversity indicators provided useful additional information to refine our under-standing of the status evaluation of 29 exploited marine ecosystems. We used state and trend analyses,and we performed correlation, redundancy and multivariate tests. Existing developments in ecosystem-based fisheries management have largely focused on exploited species. Our study, using mostly fisheries independent survey-based indicators, highlights that biodiversity and conservation-based indicators are complementary to ecological indicators of fishing pressure. Thus, they should be used to provide additional information to evaluate the overall impact of fishing on exploited marine ecosystems

    The cosmic gamma-ray bursts and their host galaxies in a cosmological context

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    Studies of the cosmic gamma-ray bursts (GRBs) and their host galaxies are now starting to provide interesting or even unique new insights in observational cosmology. Observed GRB host galaxies have a median magnitude R ∌ 25 mag, and show a range of luminosities, morphologies, and star formation rates, with a median redshift z ∌ 1.0. They represent a new way of identifying a population of star-forming galaxies at cosmological redshifts, which is mostly independent of the traditional selection methods. They seem to be broadly similar to the normal field galaxy populations at comparable redshifts and magnitudes, and indicate at most a mild luminosity evolution over the redshift range they probe. Studies of GRB optical afterglows seen in absorption provide a powerful new probe of the ISM in dense, central regions of their host galaxies, which is complementary to the traditional studies using QSO absorption line systems. Some GRB hosts are heavily obscured, and provide a new way to select a population of cosmological sub-mm sources. A census of detected optical tranistents may provide an important new way to constrain the total obscured fraction of star formation over the history of the universe. Finally, detection of GRB afterglows at high redshifts (z > 6) may provide a unique way to probe the primordial star formation, massive IMF, early IGM, and chemical enrichment at the end of the cosmic reionization era

    Ecological indicators to capture the effects of fishing on biodiversityand conservation status of marine ecosystems

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    IndiSeas (“Indicators for the Seas”) is a collaborative international working group that was established in2005 to evaluate the status of exploited marine ecosystems using a suite of indicators in a comparative framework. An initial shortlist of seven ecological indicators was selected to quantify the effects of fishing on the broader ecosystem using several criteria (i.e., ecological meaning, sensitivity to fishing, data avail-ability, management objectives and public awareness). The suite comprised: (i) the inverse coefficient of variation of total biomass of surveyed species, (ii) mean fish length in the surveyed community, (iii)mean maximum life span of surveyed fish species, (iv) proportion of predatory fish in the surveyed community, (v) proportion of under and moderately exploited stocks, (vi) total biomass of surveyed species,and (vii) mean trophic level of the landed catch. In line with the Nagoya Strategic Plan of the Convention on Biological Diversity (2011–2020), we extended this suite to emphasize the broader biodiversity and conservation risks in exploited marine ecosystems. We selected a subset of indicators from a list of empirically based candidate biodiversity indicators initially established based on ecological significance to complement the original IndiSeas indicators. The additional selected indicators were: (viii) mean intrinsic vulnerability index of the fish landed catch, (ix) proportion of non-declining exploited species in the surveyed community, (x) catch-based marine trophic index, and (xi) mean trophic level of the surveyed community. Despite the lack of data in some ecosystems, we also selected (xii) mean trophic level of the modelled community, and (xiii) proportion of discards in the fishery as extra indicators. These additional indicators were examined, along with the initial set of IndiSeas ecological indicators, to evaluate whether adding new biodiversity indicators provided useful additional information to refine our under-standing of the status evaluation of 29 exploited marine ecosystems. We used state and trend analyses,and we performed correlation, redundancy and multivariate tests. Existing developments in ecosystem-based fisheries management have largely focused on exploited species. Our study, using mostly fisheries independent survey-based indicators, highlights that biodiversity and conservation-based indicators are complementary to ecological indicators of fishing pressure. Thus, they should be used to provide additional information to evaluate the overall impact of fishing on exploited marine ecosystems

    GRB 010222: A burst within a starburst

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    We present millimeter- and submillimeter-wavelength observations and near-infrared K-band imaging toward the bright gamma-ray burst GRB 010222. Over seven different epochs, a constant source was detected with an average flux density of 3.74 ± 0.53 mJy at 350 GHz and 1.05 ± 0.22 mJy at 250 GHz, giving a spectral index α = 3.78 ± 0.25 (where F ∝ vα). We rule out the possibility that this emission originated from the burst or its afterglow, and we conclude that it is due to a dusty, high-redshift starburst galaxy (SMM J14522 + 4301). We argue that the host galaxy of GRB 010222 is the most plausible counterpart of SMM J14522+4301, based in part on the centimeter detection of the host at the expected level. The optical/near-IR properties of the host galaxy of GRB 010222 suggest that it is a blue sub-L* galaxy, similar to other GRB host galaxies. This contrasts with the enormous far-infrared luminosity of this galaxy based on our submillimeter detection (LBol ≈ 4 × 10 12 L⊙). We suggest that this GRB host galaxy has a very high star formation rate, SFR ≈ 600 M⊙ yr -1, most of which is unseen at optical wavelengths

    GRB 010921: Discovery of the first high energy transient explorer afterglow

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    We report the discovery of the optical and radio afterglow of GRB 010921, the first gamma-ray burst afterglow to be found from a localization by the High Energy Transient Explorer satellite. We present optical spectroscopy of the host galaxy, which we find to be a dusty and apparently normal star-forming galaxy at z = 0.451. The unusually steep optical spectral slope of the afterglow can be explained by heavy extinction, Av > 0.5 mag, along the line of sight to the GRB. Dust with similar Av for the host galaxy as a whole appears to be required by the measurement of a Balmer decrement in the spectrum of the host galaxy
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