Dietary intake in the Personalized Medicine Research Project: a resource for studies of gene-diet interaction

<p>Abstract</p> <p>Background</p> <p>To describe the dietary intake of participants in the Personalized Medicine Research Project (PMRP), and to quantify differences in nutrient intake by smoking status and APOE4-a genetic marker that has been shown to modify the association between risk factors and outcomes.</p> <p>Methods</p> <p>The PMRP is a population-based DNA, plasma and serum biobank of more than 20,000 adults aged 18 years and older in central Wisconsin. A questionnaire at enrollment captures demographic information as well as self-reported smoking and alcohol intake. The protocol was amended to include the collection of dietary intake and physical activity via self-reported questionnaires: the National Cancer Institute 124-item Diet History Questionnaire and the Baecke Physical Activity Questionnaire. These questionnaires were mailed out to previously enrolled participants. APOE was genotyped in all subjects.</p> <p>Results</p> <p>The response rate to the mailed questionnaires was 68.2% for subjects who could still be contacted (alive with known address). Participants ranged in age from 18 to 98 years (mean 54.7) and 61% were female. Dietary intake is variable when comparing gender, age, smoking, and APOE4. Over 50% of females are dietary supplement users; females have higher supplement intake than males, but both have increasing supplement use as age increases. Food energy, total fat, cholesterol, protein, and alcohol intake decreases as both males and females age. Female smokers had higher macronutrient intake, whereas male nonsmokers had higher macronutrient intake. Nonsmokers in both genders use more supplements. In females, nonsmokers and smokers with APOE4 had higher supplement use. In males, nonsmokers with APOE4 had higher supplement use between ages 18-39 only, and lower supplement use at ages above 39. Male smokers with APOE4 had lower supplement use.</p> <p>Conclusion</p> <p>Dietary intake in PMRP subjects is relatively consistent with data from the National Health and Nutrition Examination Survey (NHANES). Findings suggest a possible correlation between the use of supplements and APOE4. The PMRP dietary data can benefit studies of gene-environment interactions and the development of common diseases.</p

Proceedings of the 2016 ACM Conference Companion Publication on Designing Interactive Systems (Volume 2)

Welcome to the southern hemisphere, welcome to Australia, welcome to Brisbane, welcome to the picturesque Gardens Point campus of Queensland University of Technology (QUT), and welcome to the 11th ACM SIGCHI Designing Interactive Systems (DIS'16) conference! Since 1995, the (so far1) biennial Conference on Designing Interactive Systems (DIS) is the premier, international arena where designers, artists, psychologists, user experience researchers, systems engineers, and many more, come together to debate and shape the future of interactive systems design and practice. DIS is owned by the ACM Special Interest Group on Computer- Human Interaction (SIGCHI). In the past, DIS has been held in Ann Arbor (1995), Amsterdam (1997), New York (2000), London (2002), Boston (2004), State College (2006), Cape Town (2008), Aarhus (2010), Newcastle (2012), and Vancouver (2014). The DIS'16 conference schedule comprises two days of pre-conference workshops and a doctoral consortium as well as three main conference days packed with peer reviewed paper presentations, demos, panel discussions, and three invited keynote speakers. The social program includes the welcome reception on Sunday night, the DIS Experience Night on Monday night, the DIS conference dinner on Tuesday night, and a post-conference after party on Wednesday night. And for all those who still haven't had enough, the QUT School of Design has added a great satellite event held in conjunction with DIS'16: the inaugural Queensland Design Policy Summit, a full day event on Thursday 9 June, dedicated to bringing together thought leaders and policy makers across design, business, science, education, and citymaking in a dialogue to canvass the merits of resurrecting a revised, fresh, and bold Queensland Design Policy. The DIS'16 theme of "fuse" is about exploring the range of new possibilities along the human and technology spectrum -- the blurring of any clear divides between analog and digital, atoms and bits, materiality and virtuality, art and design, academy and industry. From mobiles to wearables, bearables, and even injectables, technology is finding its way to be carried by us, on by, and inside us. At the same time do we welcome more and more robots and humanoids into our lives -- from Furby, Roomba, Siri, to Jibo. Are we witnessing a fusion of the cyborg with the matrix? What does the future of interactive systems hold? We hope to advance these questions at DIS'16. I am very pleased that we were able to curate and assemble a stellar program, including three invited keynote presentations by Carlo Ratti (MIT), Natalie Jeremijenko (New York University), and Stelarc (Curtin University of Technology). I am sure they will stimulate our thinking particularly at the intersection of design and cities, the environment, and the human body

Proceedings of the 2016 ACM Conference on Designing Interactive Systems (Volume 1)

Welcome to the southern hemisphere, welcome to Australia, welcome to Brisbane, welcome to the picturesque Gardens Point campus of Queensland University of Technology (QUT), and welcome to the 11th ACM SIGCHI Designing Interactive Systems (DIS'16) conference! Since 1995, the (so far1) biennial Conference on Designing Interactive Systems (DIS) is the premier, international arena where designers, artists, psychologists, user experience researchers, systems engineers, and many more, come together to debate and shape the future of interactive systems design and practice. DIS is owned by the ACM Special Interest Group on Computer- Human Interaction (SIGCHI). In the past, DIS has been held in Ann Arbor (1995), Amsterdam (1997), New York (2000), London (2002), Boston (2004), State College (2006), Cape Town (2008), Aarhus (2010), Newcastle (2012), and Vancouver (2014). The DIS'16 conference schedule comprises two days of pre-conference workshops and a doctoral consortium as well as three main conference days packed with peer reviewed paper presentations, demos, panel discussions, and three invited keynote speakers. The social program includes the welcome reception on Sunday night, the DIS Experience Night on Monday night, the DIS conference dinner on Tuesday night, and a post-conference after party on Wednesday night. And for all those who still haven't had enough, the QUT School of Design has added a great satellite event held in conjunction with DIS'16: the inaugural Queensland Design Policy Summit, a full day event on Thursday 9 June, dedicated to bringing together thought leaders and policy makers across design, business, science, education, and citymaking in a dialogue to canvass the merits of resurrecting a revised, fresh, and bold Queensland Design Policy. The DIS'16 theme of "fuse" is about exploring the range of new possibilities along the human and technology spectrum -- the blurring of any clear divides between analog and digital, atoms and bits, materiality and virtuality, art and design, academy and industry. From mobiles to wearables, bearables, and even injectables, technology is finding its way to be carried by us, on by, and inside us. At the same time do we welcome more and more robots and humanoids into our lives -- from Furby, Roomba, Siri, to Jibo. Are we witnessing a fusion of the cyborg with the matrix? What does the future of interactive systems hold? We hope to advance these questions at DIS'16. I am very pleased that we were able to curate and assemble a stellar program, including three invited keynote presentations by Carlo Ratti (MIT), Natalie Jeremijenko (New York University), and Stelarc (Curtin University of Technology). I am sure they will stimulate our thinking particularly at the intersection of design and cities, the environment, and the human body

Book reviews including 'Cell phone culture: mobile technology in everyday life,' by Gerard Goggin

Michael Meadows reviews the book 'The electronic reporter: broadcast journalism in Australia,' 2nd ed., by Barbara Alysen, published by UNSW Press, 2005; Craig Hight reviews the book 'Documentary screens: nonfiction film and television' by Keith Beattie, published by Palgrave Macmillan, 2004; Stephen McElhinney reviews the book 'Management and creativity: from creative industies to creative management' by Chris Bilton, published by Blackwell, 2007; Lisa Grunders reviews the book 'Ordinary people's politics: Australians talk about life, politics, and the future of their country' by Judith Brett and Anthony Moran, published by Pluto Press, 2006; Rebecca Bishop reviews the book 'Women and media: a critical introduction' by Carolyn M. Byerly and Karen Ross, published by Blackwell, 2006; Kitty van Vuuren reviews the book 'Digital review of Asia Pacific 2005/2006' edited by S. Y. Chin, published by Pan Asia Networking, International Development Research Centre, Asia-Pacific Development Information Program, United Nations Development Program, Orbicom Network of UNESCO Chairs in Communication and Southbound, 2005; Dave Boreham reviews the book 'Folk devils and moral panics,' 3rd ed., by Stanely Cohen, published by Routledge, 2002; Siall Waterbright reviews the book 'Phallic panic: film horror and the primal uncanny' by Barbara Creed, published by Melbourne University Press, 2005; Stephen McElhinney reviews the esasy 'What price a creative economy?' by Stuart Cunningham, published in Platform Papers Quarterly Essays on Performing Arts, no. 9, 2006; Trevor Barr reviews the book 'Cell phone culture: mobile technology in everyday life' by Gerard Goggin, published by Routledge, 2006; John Gunders reviews the book 'Secret ingredients: race, gender and class at the dinner table' by Sherrie A. Inness, published by Palgrave Macmillan, 2006; Sandey Fitzgerald reviews the book 'Key concepts in political communication' by Darren G. Lillekar, published by Sage, 2006; Sandey Fitzgerald reviews the book 'The media and political process' by Eric Louw, published by Sage, 2005; Anne Dunn reviews the book 'Communication theory and research: an EJC anthology' by Denis McQuail, published by Sage, 2005; Wendy Davis reviews the book 'TV land: Australia's obsession with reality television' by Kerrie Murphy, published by John Wiley and Sons, 2006; Tal Azran reviews the book 'Global war: local views' edited by Stig A. Nohrstedt and Rune Ottosen, published by Goteborg University, 2005; Geoff Lealand reviews the book 'Raymond Williams' by Alan O'Connor, published by Rowman &amp; Littlefield, 2006; Jonathan Marshall reviews the book 'Digital people: from bionic humans to androids' by Sidney Perkowitz, published by Joseph Henry Press, 2005; Lucy Morieson reviews the book 'Converging media, diverging politics: a political economy of news media in the United States and Canada' edited by David Skinner, James R. Compton and Michael Gasher, published by Lexington Books, 2005; Heather Anderson reviews the book 'Crime and criminal justice: images, realities and policies,' 3rd. ed., by Ray Surette, published by Thomson Wadsworth, 2007; Marcus Foth reviews the book 'Technically together: rethinking community within techno-society' by Michele A. Willson, published by Peter Lang, 2006

The city as perpetual beta: Fostering systemic urban acupuncture

Applying the concept of perpetual beta to cities proposes a continual and never complete process of city making. Building on this notion, this chapter employs a conceptual framework of urban acupuncture for conducting and analysing localised small-scale community engagement activities through situated pop-up interventions. Pop-up interventions ‘hack’ public space by temporarily changing the feel of a place to promote awareness around civic issues. We argue that the use of situated pop-up interventions has the potential to provide more inclusive forms of community engagement by combining digital and physical media. The proposed framework employs pop-up activism to facilitate a middle-out approach that encourages citizens to actively identify topics for discussion. Two pop-up interventions in different locations in Australia are discussed in the chapter to assess in what way a systemic level of impact can arise from different processes of city hacking that are facilitated through a distributed, decentralised, yet concerted and regular local approach. We argue that a concerted process of implementing small urban interventions can contribute to an ongoing commitment to participatory city making. Further work will show how each local intervention can contribute to translating the notion of perpetual beta into systemic change beyond the boundaries of their individual locale and – taken together – across different urban environments of the city