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One of the most visited websites on the internet today is Facebook. Facebook is a social network where you have your own personal profile including status, pictures, and comments. Information for these different areas was added by the users\u27 as well as others. There were no rules regarding who can provide what information (except copyright laws). This caused issues for the users\u27 when the information could be used in a harmful way. Recently it was brought to users\u27 attention that personal information shared on Facebook is no longer private regardless of privacy settings. Companies, police departments, and school officials may have the ability to view your profile and could discriminate against you. Our research was designed to show whether or not participants know that there is no secure information on Facebook. Our survey shows the percentages of people who were aware of these terms and whether they will continue using Facebook in the same manner. Our presentation reviews our findings and discusses the rights that users of any internet site may want to be aware of

Tendon and ligament engineering in the adult organism: mesenchymal stem cells and gene-therapeutic approaches

Tendons and ligaments are elastic collagenous tissues with similar composition and hierarchical structure, contributing to motion. Their strength is related to the number and size of the collagen fibrils. Collagen fibrils increase in size during development and in response to increased physical demands or training. Tendon disorders are commonly seen in clinical practice and give rise to significant morbidity. Treatment is difficult and patients often suffer from the symptoms for quite a long time. Despite remodelling, the biochemical and mechanical properties of healed tendon tissue never match those of intact tendon. The prerequisite for focussed treatment strategies in the future will be an improved understanding of the molecular events both in the embryo and contributing to regeneration in the adult organism. Novel approaches include the local delivery of growth factors, stem- and tendon-cell-derived therapy, the application of mechanical load and gene-therapeutic approaches based on vehicles encoding selected factors, or combinations of these. Important factors are proteins of the extracellular matrix like the metalloproteinases, growth factors like the bone morphogenetic proteins but also intracellular signalling mediator proteins, such as the Smads and transcription factors from the helix–loop–helix and other families. In this review, we focus specifically on such molecular approaches based on mesenchymal stem cells