Conception et synthèse de nouveaux types d inhibiteurs des phosphomannose isomérases ( étude structure-activité par évaluations cinétiques et modélisation moléculaire )

ORSAY-PARIS 11-BU Sciences (914712101) / SudocSudocFranceF

Synthesis and evaluation of non-hydrolyzable d-mannose 6-phosphate surrogates reveal 6-deoxy-6-dicarboxymethyl-d-mannose as a new strong inhibitor of phosphomannose isomerases

International audienc

Polarizable Water Networks in Ligand–Metalloprotein Recognition. Impact on the Relative Complexation Energies of Zn-Dependent Phosphomannose Isomerase with d -Mannose 6-Phosphate Surrogates

International audienc

The reaction mechanism of type I phosphomannose isomerases: New information from inhibition and polarizable molecular mechanics studies

International audienc